Brief Information of the Compound and Protein
Compound Name
CHEMBL4459057
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Canonical SMILES
COc1ccc(Nc2ncc3[nH]c(=O)n([C@H]4CC[C@H](O)CC4)c3n2)c(C)c1
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Compound Formula C19H23N5O3
Compound Structure
Protein Name
DNA-dependent protein kinase catalytic subunit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Atypical protein kinase group
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Atypical protein kinase PIKK family
Uniprot ID
P78527
Gene Name
PRKDC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 1.995 nM
   TI
   LI
   LO
   TS