| Compound ID |
Compound Name |
Compound Formula |
|
CP0149004
|
5-(4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl)-2,2-diphenylpentanenitrile
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|
C28H29ClN2O
|
2
|
| 1 |
EC50 = 3200 nM
|
|
|
| 2 |
IC50 = 9300 nM
|
|
|
|
CP0436101
|
4-(4-Chloro-phenyl)-1-(4,4-diphenyl-butyl)-piperidin-4-ol
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|
C27H30ClNO
|
2
|
| 1 |
EC50 = 4200 nM
|
|
|
| 2 |
IC50 = 6500 nM
|
|
|
|
CP0455657
|
4-(4-Chloro-phenyl)-1-(4-phenyl-4-o-tolyl-butyl)-piperidin-4-ol
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|
C28H32ClNO
|
2
|
| 1 |
EC50 = 9800 nM
|
|
|
| 2 |
IC50 = 5500 nM
|
|
|
|
CP0515626
|
4-(4-Chloro-phenyl)-1-(4-phenyl-4-p-tolyl-butyl)-piperidin-4-ol
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|
C28H32ClNO
|
2
|
| 1 |
EC50 = 11500 nM
|
|
|
| 2 |
IC50 = 30900 nM
|
|
|
|
CP0490729
|
5-[4-(4-Chloro-phenyl)-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
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|
C28H29ClN2
|
2
|
| 1 |
EC50 = 13800 nM
|
|
|
| 2 |
IC50 = 10500 nM
|
|
|
|
CP0428273
|
5-(4-Hydroxy-4-phenyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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|
C28H30N2O
|
2
|
| 1 |
EC50 = 28200 nM
|
|
|
| 2 |
IC50 = 35500 nM
|
|
|
|
CP0389170
|
5-[4-Hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
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|
C29H32N2O2
|
2
|
| 1 |
EC50 = 28800 nM
|
|
|
| 2 |
IC50 = 72400 nM
|
|
|
|
CP0378237
|
1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carboxylic acid ethyl ester
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|
C25H30N2O2
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 34700 nM
|
|
|
|
CP0378238
|
5-(4-Benzhydrylidene-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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|
C35H34N2
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0392112
|
5-[4-(4-Chloro-phenyl)-piperazin-1-yl]-2,2-diphenyl-pentanenitrile
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|
C27H28ClN3
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0392113
|
5-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-2,2-diphenyl-pentanenitrile
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|
C28H27ClN2
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0436103
|
1-[4-Biphenyl-4-yl-4-(4-chloro-phenyl)-butyl]-4-(4-chloro-phenyl)-piperidin-4-ol
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|
C33H33Cl2NO
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0442708
|
1-(4-Cyano-4,4-diphenyl-butyl)-4-phenyl-piperidine-4-carbonitrile
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|
C29H29N3
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0442709
|
4-(4-Chloro-phenyl)-1-(4-hydroxy-4-phenyl-butyl)-piperidin-4-ol
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|
C21H26ClNO2
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0445792
|
5-(4-Butyl-4-hydroxy-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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|
C26H34N2O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0446390
|
5-(4-Hydroxy-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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|
C22H26N2O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0446391
|
4-(4-Chloro-phenyl)-1-(4-cyano-4,4-diphenyl-butyl)-4-hydroxy-1-methyl-piperidinium
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|
C29H32ClN2O+
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0493099
|
1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carboxylic acid amide
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|
C23H27N3O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0540279
|
5-(4-Hydroxy-4-methyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
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|
C23H28N2O
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0541527
|
1-(4-Cyano-4,4-diphenyl-butyl)-piperidine-4-carboxylic acid
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|
C23H26N2O2
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0486612
|
4-(4-Chloro-phenyl)-1-(4-phenyl-4-m-tolyl-butyl)-piperidin-4-ol
Show/Hide
|
C28H32ClNO
|
1
|
| 1 |
IC50 = 11500 nM
|
|
|
|
CP0476709
|
4-(4-Chloro-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol
Show/Hide
|
C21H26ClNO
|
1
|
| 1 |
IC50 = 14800 nM
|
|
|
|
CP0403411
|
4-(4-Chloro-phenyl)-1-[4-(4-methoxy-phenyl)-4-phenyl-butyl]-piperidin-4-ol
Show/Hide
|
C28H32ClNO2
|
1
|
| 1 |
IC50 = 15500 nM
|
|
|
|
CP0378239
|
4-(4-Chloro-phenyl)-1-[4-(3,4-dichloro-phenyl)-4-phenyl-butyl]-piperidin-4-ol
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|
C27H28Cl3NO
|
1
|
| 1 |
IC50 = 15800 nM
|
|
|
|
CP0436102
|
4-(4-Chloro-phenyl)-1-[4-(4-chloro-phenyl)-4-phenyl-butyl]-piperidin-4-ol
Show/Hide
|
C27H29Cl2NO
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0486611
|
1-[4,4-Bis-(4-chloro-phenyl)-butyl]-4-(4-chloro-phenyl)-piperidin-4-ol
Show/Hide
|
C27H28Cl3NO
|
1
|
| 1 |
IC50 = 17400 nM
|
|
|
|
CP0403418
|
5-[4-(4-Bromo-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
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|
C28H29BrN2O
|
1
|
| 1 |
IC50 = 19500 nM
|
|
|
|
CP0392092
|
5-[4-(3,4-Dichloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
Show/Hide
|
C28H28Cl2N2O
|
1
|
| 1 |
IC50 = 38000 nM
|
|
|
|
CP0495173
|
5-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
Show/Hide
|
C29H28ClF3N2O
|
1
|
| 1 |
IC50 = 45700 nM
|
|
|
|
CP0485050
|
5-(4-Hydroxy-4-p-tolyl-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
Show/Hide
|
C29H32N2O
|
1
|
| 1 |
IC50 = 60300 nM
|
|
|
|
CP0392114
|
4-(4-Chloro-phenyl)-1-(3-phenoxy-propyl)-piperidin-4-ol
Show/Hide
|
C20H24ClNO2
|
1
|
| 1 |
IC50 = 61700 nM
|
|
|
|
CP0442707
|
5-(4-Benzyl-4-hydroxy-piperidin-1-yl)-2,2-diphenyl-pentanenitrile
Show/Hide
|
C29H32N2O
|
1
|
| 1 |
IC50 = 63100 nM
|
|
|
|
CP0421011
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-phenyl-butan-1-one
Show/Hide
|
C21H24ClNO2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
