Compound ID |
Compound Name |
Compound Formula |
CP0134612
|
GHRELIN
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|
C147H245N45O42
|
2
|
1 |
EC50 = 1.4 nM
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|
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2 |
Ki = 0.7 nM
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|
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CP0507777
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1-benzothiophen-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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C51H66N8O6S
|
1
|
1 |
EC50 = 2.1 nM
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|
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CP0158770
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
10
|
1 |
EC50 = 2.8 nM
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|
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2 |
EC50 = 3.3 nM
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|
|
3 |
EC50 = 3.4 nM
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|
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4 |
EC50 = 3.8 nM
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|
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5 |
EC50 = 7.2 nM
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|
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6 |
EC50 = 11.2 nM
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|
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7 |
EC50 = 29.6 nM
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|
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8 |
EC50 = 237.6 nM
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|
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9 |
EC50 > 1000 nM
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10 |
Ki = 4.9 nM
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CP0413879
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1-benzothiophen-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C49H65N9O6S
|
1
|
1 |
EC50 = 5.7 nM
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|
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CP0392263
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
5
|
1 |
EC50 = 6.7 nM
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|
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2 |
EC50 = 7.2 nM
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|
|
3 |
EC50 = 12.6 nM
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|
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4 |
EC50 = 13.4 nM
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|
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5 |
Ki = 234.2 nM
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CP0456720
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1-benzothiophen-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1-benzothiophen-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C49H64N8O6S2
|
1
|
1 |
EC50 = 9.4 nM
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|
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CP0392267
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]hexanamide
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|
C53H69N9O6
|
1
|
1 |
EC50 = 13.1 nM
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|
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CP0481695
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
2
|
1 |
EC50 = 17.9 nM
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|
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2 |
Ki = 247.2 nM
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|
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CP0379087
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C49H66N10O6
|
14
|
1 |
EC50 = 45.6 nM
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|
|
2 |
IC50 = 2.6 nM
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|
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3 |
IC50 = 13 nM
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4 |
IC50 = 19 nM
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5 |
IC50 = 21 nM
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6 |
IC50 = 27 nM
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7 |
IC50 = 29 nM
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8 |
IC50 = 32 nM
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9 |
IC50 = 36 nM
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10 |
IC50 = 43 nM
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|
|
11 |
IC50 = 60 nM
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|
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12 |
IC50 = 61 nM
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13 |
IC50 = 83 nM
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|
14 |
IC50 > 1000 nM
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CP0486933
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C51H73N9O6
|
1
|
1 |
EC50 = 96.8 nM
|
|
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CP0445284
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
1
|
1 |
EC50 = 119.6 nM
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|
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CP0456719
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-tert-butylphenyl)-1-oxopropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C55H75N9O6
|
1
|
1 |
EC50 = 124.1 nM
|
|
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CP0392266
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]hexanamide
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|
C51H67N9O6
|
1
|
1 |
EC50 = 161.3 nM
|
|
|
CP0381580
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-benzoylphenyl)-1-oxopropan-2-yl]hexanamide
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|
C54H69N9O7
|
1
|
1 |
EC50 = 168.6 nM
|
|
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CP0392265
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]hexanamide
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|
C53H69N9O6
|
1
|
1 |
EC50 = 183.7 nM
|
|
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CP0392273
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]hexanamide
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|
C47H65N9O6
|
1
|
1 |
EC50 = 240.9 nM
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|
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CP0445286
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C47H67N9O6
|
1
|
1 |
EC50 = 498.1 nM
|
|
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CP0392264
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4-tert-butylphenyl)-1-oxopropan-2-yl]hexanamide
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|
C51H73N9O6
|
1
|
1 |
EC50 = 624.4 nM
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|
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CP0392270
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1-methylindol-3-yl)-1-oxopropan-2-yl]hexanamide
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|
C50H68N10O6
|
2
|
1 |
EC50 > 1000 nM
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2 |
Ki = 22.1 nM
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CP0392272
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(2S)-2,6-diamino-N-[(2R)-1-[[(1S)-2-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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|
C50H65N9O6
|
1
|
1 |
EC50 > 1000 nM
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|
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CP0413881
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(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1-benzothiophen-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C49H65N9O6S
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2
|
1 |
EC50 > 1000 nM
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2 |
Ki = 31.3 nM
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CP0445285
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C53H68N8O6
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2
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1 |
EC50 > 1000 nM
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2 |
Ki = 34.9 nM
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CP0456718
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C53H69N9O6
|
2
|
1 |
EC50 > 1000 nM
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|
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2 |
IC50 >= 1000 nM
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CP0486932
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-(4-phenylphenyl)propan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C53H69N9O6
|
2
|
1 |
EC50 > 1000 nM
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2 |
IC50 >= 1000 nM
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CP0534547
|
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-benzoylphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]hexanamide
Show/Hide
|
C54H69N9O7
|
2
|
1 |
EC50 > 1000 nM
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|
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2 |
IC50 >= 1000 nM
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CP0852283
|
(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-6-amino-hexanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methyl-pentanoyl]amino]-4-amino-4-oxo-butanoyl]amino]-4-methyl-pentanoyl]amino]-4-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]-5-guanidino-pentanoyl]amino]-N-[(1S)-1-[[(1S)-2-amino-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]pentanediamide
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|
C87H143N29O20
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1
|
1 |
EC50 > 1000 nM
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|
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CP0372445
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AwFwLL-NH2
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C46H59N9O6
|
10
|
1 |
IC50 = 0.35 nM
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2 |
IC50 = 6.1 nM
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3 |
IC50 = 14 nM
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4 |
IC50 = 15 nM
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5 |
IC50 = 28 nM
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6 |
IC50 = 41 nM
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7 |
IC50 = 53 nM
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8 |
IC50 = 81 nM
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9 |
IC50 = 160 nM
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10 |
IC50 > 1000 nM
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CP0422017
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(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide
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C79H109N19O12
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2
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1 |
IC50 = 3.2 nM
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2 |
IC50 = 18 nM
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CP0384665
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(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide
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|
C49H66N12O6
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2
|
1 |
IC50 = 12 nM
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2 |
IC50 = 21 nM
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CP0434533
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(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide
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|
C49H61N11O6
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2
|
1 |
IC50 = 58 nM
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2 |
IC50 = 68 nM
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CP0379082
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(3S)-3-amino-4-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
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|
C47H59N9O8
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2
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1 |
IC50 = 60 nM
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2 |
IC50 = 260 nM
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CP0422019
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(3S)-3-amino-4-[(2R)-2-[[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxobutanoic acid
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|
C58H78N14O10
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2
|
1 |
IC50 = 112 nM
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2 |
IC50 = 210 nM
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CP0384664
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(2S)-2-amino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide
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|
C48H62N10O7
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2
|
1 |
IC50 = 120 nM
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|
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2 |
IC50 = 990 nM
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CP0434534
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(2S)-2-[[(2R)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-3-phenylpropanamide
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|
C35H38N8O5
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2
|
1 |
IC50 = 159 nM
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|
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2 |
IC50 = 540 nM
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CP0392268
|
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide
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C43H54N8O5
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2
|
1 |
IC50 = 530 nM
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2 |
IC50 > 1000 nM
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CP0379085
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(2S)-2-[[(2R)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-3-phenylpropanamide
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C37H42N8O5
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1
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1 |
IC50 > 1000 nM
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