Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2,6-diamino-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]hexanamide
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 PubChem ID
CID: 71453489
SID: 163441169
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)[C@@H](N)CCCCN)C(N)=O
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Compound Formula C51H67N9O6
Compound Structure
Protein Name
 Protein Info 
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GRP-related receptor
Uniprot ID
Q92847
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  10
1
EC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
EC50 = 3.3 nM
   TI
   LI
   LO
   TS
3
EC50 = 3.4 nM
   TI
   LI
   LO
   TS
4
EC50 = 3.8 nM
   TI
   LI
   LO
   TS
5
EC50 = 7.2 nM
   TI
   LI
   LO
   TS
6
EC50 = 11.2 nM
   TI
   LI
   LO
   TS
7
EC50 = 29.6 nM
   TI
   LI
   LO
   TS
8
EC50 = 237.6 nM
   TI
   LI
   LO
   TS
9
EC50 > 1000 nM
   TI
   LI
   LO
   TS
10
Ki = 4.9 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 5.5 nM
   TI
   LI
   LO
   TS
2
Ki = 3.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS