| Compound ID |
Compound Name |
Compound Formula |
|
CP0544513
|
2-[4-(3-methoxy-4-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H28N6O2
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0514974
|
2-[4-(4-fluoro-3,5-dimethylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H27FN6O
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0431966
|
2-[4-(4-fluoro-3-methylphenyl)-2-(4-fluorophenyl)imidazol-1-yl]-1-(2-methyl-4,6,7,7a-tetrahydro-3aH-[1,3]oxazolo[5,4-c]pyridin-5-yl)ethanone
Show/Hide
|
C25H24F2N4O2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0390036
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C26H25FN6O
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0419790
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-[4-(5-methoxypyrimidin-2-yl)piperazin-1-yl]ethanone
Show/Hide
|
C27H27FN6O2
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0545232
|
2-[4-(4-fluoro-3-methylphenyl)-2-(4-fluorophenyl)imidazol-1-yl]-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H25F2N5O
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0419789
|
2-[4-(4-chloro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C26H25ClN6O
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0424156
|
1-(4-fluorophenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one
Show/Hide
|
C18H14FN3O2
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0420197
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(2-methyl-6,7-dihydro-4H-[1,3]oxazolo[4,5-c]pyridin-5-yl)ethanone
Show/Hide
|
C25H23FN4O2
|
1
|
| 1 |
EC50 = 61 nM
|
|
|
|
CP0514975
|
2-[4-(4-fluoro-3-methylphenyl)-2-(4-fluorophenyl)imidazol-1-yl]-1-(2-methyl-4,6-dihydropyrrolo[3,4-d][1,3]thiazol-5-yl)ethanone
Show/Hide
|
C24H20F2N4OS
|
1
|
| 1 |
EC50 = 64 nM
|
|
|
|
CP0411336
|
2-[4-(4-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C26H26N6O
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0426558
|
2-[4-(3-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H27N5O
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
|
CP0379751
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H26FN5O
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0483409
|
(R)-cyclopropyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0431965
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-[4-(4-methoxypyridin-2-yl)piperazin-1-yl]ethanone
Show/Hide
|
C28H28FN5O2
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0437840
|
1-(4-fluorophenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13F2N3O2
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0404515
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(2-methyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-6-yl)ethanone
Show/Hide
|
C26H25FN4OS
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0442323
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(2-methyl-4,6,7,7a-tetrahydro-3aH-[1,3]oxazolo[5,4-c]pyridin-5-yl)ethanone
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0404415
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]ethanone
Show/Hide
|
C26H24F2N6O
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0437844
|
1-(4-chlorophenyl)-4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13Cl2N3O2
|
2
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0377565
|
1-(4-chlorophenyl)-4-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O2
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0484294
|
1-(2-amino-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-6-yl)-2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]ethanone
Show/Hide
|
C25H24FN5OS
|
1
|
| 1 |
EC50 = 224 nM
|
|
|
|
CP0458257
|
1-(3-chloro-4-methylphenyl)-4-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C20H18ClN3O2
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0544514
|
2-[4-(4-fluorophenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C25H23FN6O
|
1
|
| 1 |
EC50 = 272 nM
|
|
|
|
CP0441348
|
(R)-cyclopentyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H22FN3O2
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0377561
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3,4-dimethylphenyl)pyrrolidin-2-one
Show/Hide
|
C20H18ClN3O2
|
2
|
| 1 |
EC50 = 310 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0523031
|
1-phenyl-4-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one
Show/Hide
|
C18H15N3O2
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0507318
|
1-(4-methylphenyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
EC50 = 384 nM
|
|
|
|
CP0377568
|
1-(3,4-dichlorophenyl)-4-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C19H15Cl2N3O2
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0456298
|
(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)(thiophen-2-yl)methanone
Show/Hide
|
C17H14FN3O2S
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0545233
|
3-[4-[2-[4-(4-fluoro-3-methylphenyl)-2-(4-fluorophenyl)imidazol-1-yl]acetyl]-2-oxopiperazin-1-yl]benzonitrile
Show/Hide
|
C29H23F2N5O2
|
1
|
| 1 |
EC50 = 431 nM
|
|
|
|
CP0498992
|
(R)-(3-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H17F2N3O2
|
1
|
| 1 |
EC50 = 460 nM
|
|
|
|
CP0377573
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3,4-dichlorophenyl)pyrrolidin-2-one
Show/Hide
|
C18H12Cl3N3O2
|
2
|
| 1 |
EC50 = 460 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0503301
|
(R)-cyclobutyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0437841
|
1-(4-chlorophenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13ClFN3O2
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0437843
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-methylphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O2
|
2
|
| 1 |
EC50 = 630 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0482504
|
2-[4-(4-ethoxyphenyl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H28N6O2
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0532434
|
(S)-cyclobutyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0389949
|
2-[2-cyclohexyl-4-(4-fluoro-3-methylphenyl)imidazol-1-yl]-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H32FN5O
|
1
|
| 1 |
EC50 = 717 nM
|
|
|
|
CP0404416
|
N-[6-[2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]acetyl]-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-yl]acetamide
Show/Hide
|
C27H26FN5O2S
|
1
|
| 1 |
EC50 = 769 nM
|
|
|
|
CP0404414
|
2-[4-(4-fluoro-3-methylphenyl)-2-phenylimidazol-1-yl]-1-(4-pyridazin-3-ylpiperazin-1-yl)ethanone
Show/Hide
|
C26H25FN6O
|
1
|
| 1 |
EC50 = 858 nM
|
|
|
|
CP0387330
|
2-[4-(4-methyl-2,3-dihydro-1,4-benzoxazin-7-yl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C28H29N7O2
|
1
|
| 1 |
EC50 = 914 nM
|
|
|
|
CP0465959
|
cyclopentyl-[2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0377574
|
1-(4-fluorophenyl)-4-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C19H16FN3O3
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0526755
|
4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3,4-dichlorophenyl)pyrrolidin-2-one
Show/Hide
|
C18H12Cl3N3O2
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0493826
|
4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-methylphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16FN3O2
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0452259
|
1-(4-methylphenyl)-4-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0483408
|
(R)-(3,4-difluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0879017
|
cyclobutyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0420220
|
2-[4-(3-methylbenzimidazol-5-yl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Show/Hide
|
C27H26N8O
|
1
|
| 1 |
EC50 = 1527 nM
|
|
|
|
CP0507416
|
1-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13ClFN3O2
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0512181
|
1-(3,4-dichlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H12Cl2FN3O2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0462775
|
(3-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C19H15F2N3O2
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0498990
|
cyclobutyl-[2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0462776
|
cyclopropyl-[2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Show/Hide
|
C16H16FN3O2
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0486673
|
(R)-(2,4-difluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0424297
|
1-(3,4-dichlorophenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H12Cl2FN3O2
|
1
|
| 1 |
EC50 = 3200 nM
|
|
|
|
CP0508742
|
1-(4-methylphenyl)-4-[3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
|
CP0498991
|
(R)-cyclohexyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H24FN3O2
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0524600
|
(4-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C19H15F2N3O2
|
1
|
| 1 |
EC50 = 3600 nM
|
|
|
|
CP0438193
|
(3,4-difluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C19H14F3N3O2
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0425981
|
1-(4-chlorophenyl)-4-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O3
|
1
|
| 1 |
EC50 = 4800 nM
|
|
|
|
CP0483423
|
(S)-cyclobutyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
EC50 = 7000 nM
|
|
|
|
CP0512460
|
(2,4-difluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone
Show/Hide
|
C19H14F3N3O2
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0524599
|
cyclohexyl-[2-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Show/Hide
|
C19H22FN3O2
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0377570
|
3-[[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]-1,3-benzothiazol-2-one
Show/Hide
|
C16H10ClN3O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0377575
|
1-(4-chlorophenyl)-4-[3-(6-methylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H15ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0377576
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(2-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 630 nM
|
|
|
|
CP0383713
|
1-(3-chlorophenyl)-4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13Cl2N3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0383714
|
4-[2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C18H14ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 800 nM
|
|
|
|
CP0416292
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(2-fluorophenyl)pyrrolidin-2-one
Show/Hide
|
C18H13ClFN3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0416346
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 690 nM
|
|
|
|
CP0424296
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(2-methylphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 370 nM
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|
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CP0425980
|
1-(4-fluorophenyl)-4-[3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C19H13F4N3O2
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
|
CP0437842
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3-[[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]-1,3-benzoxazol-2-one
Show/Hide
|
C16H10ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 2100 nM
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|
|
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CP0443555
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4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 3520 nM
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|
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CP0443556
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4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3-methylphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClN3O2
|
2
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 = 2300 nM
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|
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CP0452257
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7-chloro-1-[2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C19H15Cl2N3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 550 nM
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|
|
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CP0452258
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1-(4-fluorophenyl)-4-[3-(6-methylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H15FN4O2
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
|
CP0458246
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1-(2-chlorophenyl)-4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-2-one
Show/Hide
|
C18H13Cl2N3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 680 nM
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|
|
|
CP0458247
|
4-[[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]-1,4-benzoxazin-3-one
Show/Hide
|
C17H12ClN3O3
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 770 nM
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|
|
|
CP0493825
|
1-(4-fluorophenyl)-4-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one
Show/Hide
|
C17H13FN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0483422
|
(R)-(4-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H17F2N3O2
|
1
|
| 1 |
EC50 = 23000 nM
|
|
|
|
CP0503297
|
(S)-cyclobutyl(2-(3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0486668
|
(S)-(3-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)(cyclobutyl)methanone
Show/Hide
|
C18H20ClN3O2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0462772
|
(R)-cyclopropyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C18H21N3O2
|
2
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
|
CP0498989
|
(R)-cyclobutyl(2-(3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0532433
|
(R)-cyclobutyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0498725
|
(S)-cyclobutyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0441347
|
(R)-cyclopentyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0498987
|
(S)-cyclobutyl(3-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0456299
|
(R)-thiophen-2-yl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0512461
|
(S)-(2-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)(cyclobutyl)methanone
Show/Hide
|
C18H20ClN3O2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0424157
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(2-methylpropyl)pyrrolidin-2-one
Show/Hide
|
C16H18ClN3O2
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0493827
|
(4R)-4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-[(1R)-1-phenylethyl]pyrrolidin-2-one
Show/Hide
|
C20H18ClN3O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0486670
|
(S)-cyclobutyl(3-(3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0422851
|
(S)-cyclobutyl(3-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0503299
|
cyclobutyl-[2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]methanone
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0483420
|
(R)-cyclohexyl(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0494456
|
(S)-cyclobutyl(2-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C16H19N3O2S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0486669
|
(R)-(3-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)(cyclobutyl)methanone
Show/Hide
|
C18H20ClN3O2
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0504377
|
(R)-cyclobutyl(2-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C16H19N3O2S
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0420941
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-[(4-fluorophenyl)methyl]pyrrolidin-2-one
Show/Hide
|
C19H15ClFN3O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0422852
|
(R)-cyclobutyl(3-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0483418
|
(R)-(3-fluorophenyl)(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C21H20FN3O2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0462773
|
(S)-cyclobutyl(3-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C16H19N3O2S
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0422850
|
(R)-cyclobutyl(3-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0483421
|
(R)-(3,4-difluorophenyl)(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C21H19F2N3O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0486671
|
(R)-cyclobutyl(3-(3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0494108
|
(R)-(2-(3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)(cyclobutyl)methanone
Show/Hide
|
C18H20ClN3O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0494454
|
(S)-cyclobutyl(3-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0503298
|
[2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]-cyclobutylmethanone
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0503300
|
(R)-(4-fluorophenyl)(2-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C21H20FN3O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0504376
|
(R)-cyclobutyl(3-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0532432
|
(S)-cyclobutyl(2-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0163927
|
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(4-fluorophenyl)pyrrolidin-2-one
Show/Hide
|
C18H13ClFN3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
