Brief Information of the Compound and Protein
Compound Name
3-[4-[2-[4-(4-fluoro-3-methylphenyl)-2-(4-fluorophenyl)imidazol-1-yl]acetyl]-2-oxopiperazin-1-yl]benzonitrile
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PubChem ID
CID: 71656937
Canonical SMILES
Cc1cc(ccc1F)-c1cn(CC(=O)N2CCN(C(=O)C2)c2cccc(c2)C#N)c(n1)-c1ccc(F)cc1
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Compound Formula C29H23F2N5O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
EC50 = 431 nM
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