Brief Information of the Compound and Protein
Compound Name
2-[4-(4-methyl-2,3-dihydro-1,4-benzoxazin-7-yl)-2-phenylimidazol-1-yl]-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
    Show/Hide
PubChem ID
CID: 71585818
SID: 163638008
Canonical SMILES
CN1CCOc2cc(ccc12)-c1cn(CC(=O)N2CCN(CC2)c2ncccn2)c(n1)-c1ccccc1
    Show/Hide
Compound Formula C28H29N7O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
EC50 = 914 nM
   TI
   LI
   LO
   TS