Brief Information of the Compound and Protein
Compound Name
4-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-(3-methoxyphenyl)pyrrolidin-2-one
    Show/Hide
PubChem ID
CID: 44090528
SID: 163453166
Canonical SMILES
COc1cccc(c1)N1CC(CC1=O)c1nc(no1)-c1cccc(Cl)c1
    Show/Hide
Compound Formula C19H16ClN3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 690 nM
   TI
   LI
   LO
   TS