Brief Information of the Cell Line and Protein
Cell Line ID: CL000047 , 108CC15
Synonyms
NG108-15
NG-108-15
NG 108-15
NG10815
Category Hybrid cell line
Organism
Mus musculus (Mouse)--NCBI_TaxID=10116;
Cellosaurus ID
CVCL_0464
Protein ID: PT01354 , 5-hydroxytryptamine receptor 6
Gene Name HTR6
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P50406
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000047  Protein ID: PT01354
 
Compound ID Compound Name Compound Formula
CP0073333
3-benzenesulfonyl-8-piperazin-1-ylquinoline
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C19H19N3O2S
 2
1
IC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 97 nM
   TI
   LI
   LO
   TS
CP0073332
2-ethyl-3-[(3-fluorophenyl)methyl]-7-piperazin-1-ylimidazo[4,5-b]pyridine
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C19H22FN5
 1
1
IC50 = 17.6 nM
   TI
   LI
   LO
   TS
CP0417452
3-[(3-chlorophenyl)methyl]-2-ethyl-7-piperazin-1-ylimidazo[4,5-b]pyridine
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C19H22ClN5
 1
1
IC50 = 51.9 nM
   TI
   LI
   LO
   TS
CP0417454
3-[(3-chlorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
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C20H24ClN5
 1
1
IC50 = 56.4 nM
   TI
   LI
   LO
   TS
CP0389653
3-[(3-fluorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
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C20H24FN5
 1
1
IC50 = 69.5 nM
   TI
   LI
   LO
   TS
CP0301336
N-[[4-[5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]pentoxy]phenyl]methyl]-N-methylprop-2-yn-1-amine
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C34H40N4O3S
 1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS