Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(3-fluorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
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 PubChem ID
CID: 126720403
Canonical SMILES
CC(C)c1nc2c(ccnc2n1Cc1cccc(F)c1)N1CCNCC1
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Compound Formula C20H24FN5
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000047 108CC15
 Cell Line Info 
Mus musculus (Mouse)--NCBI_TaxID=10116;  1
1
IC50 = 69.5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 13 nM
   TI
   LI
   LO
   TS