| Compound ID |
Compound Name |
Compound Formula |
|
CP0151541
|
(4S)-2-amino-4-(4-fluoro-3-(2-fluoropyridin-3-yl)phenyl)-4-(4-methoxy-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one
Show/Hide
|
C23H20F2N4O2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0039244
|
2-amino-4-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-4-(4-methoxy-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one
Show/Hide
|
C22H20FN5O2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0666749
|
5-Adamantan-1-yl-2-amino-5-(3-ethyl-4-methoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0727251
|
2-amino-4-(4-fluoro-3-(2-fluoropyridin-3-yl)phenyl)-4-(4-methoxy-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one
Show/Hide
|
C23H20F2N4O2
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0001481
|
(S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0175001
|
(5R)-2-amino-5-(4-fluoro-3-pyrimidin-5-ylphenyl)-3-methyl-5-[4-(trifluoromethoxy)phenyl]-3,5-dihydro-4H-imidazol-4-one
Show/Hide
|
C21H15F4N5O2
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0164564
|
2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-4-(3-(pyrimidin-5-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C22H21N5O2
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0195547
|
2-amino-4-(3-(2-fluoropyridin-3-yl)phenyl)-4-(4-methoxy-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one
Show/Hide
|
C23H21FN4O2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0128509
|
2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H22N4O2
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0281090
|
(S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0151543
|
2-amino-4-(3-chloro-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C22H19ClN4O2
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0197786
|
5-Adamantan-1-yl-2-amino-5-(3,4-dimethoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0136093
|
2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-4-(4-methyl-3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0714489
|
5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0718005
|
2-amino-4-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C21H15F4N5O2
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0071364
|
2-amino-4-(4-methoxy-3-(trifluoromethyl)phenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H19F3N4O2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0130805
|
2-amino-4-(3-(2-fluoropyridin-3-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C22H16F4N4O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0166459
|
2-amino-4-(2,3-dihydrobenzofuran-5-yl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H20N4O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0048900
|
5-Adamantan-1-yl-2-amino-5-(4-ethoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0166492
|
2-amino-4-(3-fluoro-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C22H19FN4O2
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0071354
|
2-amino-4-(3-ethoxy-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C24H24N4O3
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0151621
|
5-Adamantan-1-yl-2-amino-5-(4-butoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
EC50 = 570 nM
|
|
|
|
CP0174999
|
2-amino-4-(3-cyclopentyl-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C27H28N4O2
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0166436
|
2-amino-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
EC50 = 670 nM
|
|
|
|
CP0166493
|
2-amino-4-(3-butoxy-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C26H28N4O3
|
1
|
| 1 |
EC50 = 670 nM
|
|
|
|
CP0166494
|
2-amino-4-(4-methoxy-3-propoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0192422
|
2-amino-4-(benzo[d][1,3]dioxol-5-yl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C22H18N4O3
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0097788
|
5-Adamantan-1-yl-2-amino-5-(3-ethyl-4-methoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
|
CP0151622
|
2-amino-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H20N4O3
|
1
|
| 1 |
EC50 = 860 nM
|
|
|
|
CP0151546
|
2-amino-4-(3-isopropoxy-4-methoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
EC50 = 870 nM
|
|
|
|
CP0151548
|
5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluoromethoxy-phenyl)-3,5-diydro-imidazol-4-one
Show/Hide
|
C21H24F3N3O2
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
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CP0166455
|
2-amino-4-(3,4-dimethoxyphenyl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0104399
|
5-Adamantan-1-yl-2-amino-3-methyl-5-phenyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0011000
|
(R)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0038376
|
(4R)-2-amino-4-(4-fluoro-3-(2-fluoropyridin-3-yl)phenyl)-4-(4-methoxy-3-methylphenyl)-1-methyl-1H-imidazol-5(4H)-one
Show/Hide
|
C23H20F2N4O2
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0071361
|
4-(2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-2-(pyridin-3-yl)benzonitrile
Show/Hide
|
C24H21N5O2
|
1
|
| 1 |
EC50 = 1750 nM
|
|
|
|
CP0104396
|
(R)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-3-methyl-phenyl)-3-methyl-3,5-dihydro-imidazol-4-one
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0195526
|
2-amino-4-(4-chlorophenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one
Show/Hide
|
C16H14ClN3O
|
1
|
| 1 |
EC50 = 2130 nM
|
|
|
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CP0281091
|
2-amino-4-(3-(2-methoxypyridin-3-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H19F3N4O3
|
1
|
| 1 |
EC50 = 2570 nM
|
|
|
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CP0130806
|
(S)-2-amino-4-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C21H15F4N5O2
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
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CP0071369
|
2-amino-4-(2-fluoro-3-(pyrimidin-5-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C21H15F4N5O2
|
1
|
| 1 |
EC50 = 2830 nM
|
|
|
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CP0130802
|
2-amino-4-(4-methoxyphenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
EC50 = 3350 nM
|
|
|
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CP0039686
|
1-methyl-4,4-diphenyl-4,5-dihydro-1H-imidazol-2-amine
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
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CP0136163
|
5-(2-amino-1-methyl-5-oxo-4-(3-(pyridin-3-yl)phenyl)-4,5-dihydro-1H-imidazol-4-yl)-2-methoxybenzonitrile
Show/Hide
|
C23H19N5O2
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
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CP0303292
|
2-amino-4-(3-(6-methoxypyridin-3-yl)phenyl)-1-methyl-4-(4-(trifluoromethoxy)phenyl)-1H-imidazol-5(4H)-one
Show/Hide
|
C23H19F3N4O3
|
1
|
| 1 |
EC50 = 4840 nM
|
|
|
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CP0048899
|
2-amino-4-(3-methoxyphenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
EC50 = 5900 nM
|
|
|
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CP0097791
|
2-amino-4-(3-chlorophenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one
Show/Hide
|
C16H14ClN3O
|
1
|
| 1 |
EC50 = 6970 nM
|
|
|
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CP0097799
|
2-amino-1-ethyl-4,4-diphenyl-1H-imidazol-5(4H)-one
Show/Hide
|
C17H17N3O
|
1
|
| 1 |
EC50 = 8130 nM
|
|
|
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CP0166457
|
2-Imino-5,5-diphenyl-imidazolidin-4-one
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 = 23500 nM
|
|
|
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CP0090773
|
8,8-diphenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine
Show/Hide
|
C18H18N4
|
1
|
| 1 |
IC50 = 27000 nM
|
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|
