Brief Information of the Compound and Protein
Compound Name
4-(2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl)-2-(pyridin-3-yl)benzonitrile
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PubChem ID
CID: 11560610
SID: 16662863
Canonical SMILES
COc1ccc(cc1C)C1(N=C(N)N(C)C1=O)c1ccc(C#N)c(c1)-c1cccnc1
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Compound Formula C24H21N5O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1750 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 630 nM