Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-amino-4-(2,3-dihydrobenzofuran-5-yl)-1-methyl-4-(3-(pyridin-3-yl)phenyl)-1H-imidazol-5(4H)-one
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 PubChem ID
CID: 11668120
SID: 16771959
Canonical SMILES
CN1C(N)=NC(C1=O)(c1ccc2OCCc2c1)c1cccc(c1)-c1cccnc1
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Compound Formula C23H20N4O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 119.95 nM
2 IC50 = 120 nM