Brief Information of the Compound and Protein
Compound Name
2-amino-4-(3-chlorophenyl)-1-methyl-4-phenyl-1H-imidazol-5(4H)-one
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PubChem ID
CID: 45488113
SID: 96032896
Canonical SMILES
CN1C(N)=NC(C1=O)(c1ccccc1)c1cccc(Cl)c1
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Compound Formula C16H14ClN3O
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 6970 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2500 nM
2 IC50 = 2500.35 nM
3 Ki = 300 nM