| Compound ID |
Compound Name |
Compound Formula |
|
CP0474271
|
(2R,4R)-9-[(4-fluorophenyl)methyl]-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C24H24FN3O
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0420845
|
3-(3-(2-Cyano-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
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|
C26H20FN5O2
|
1
|
| 1 |
EC50 = 0.33 nM
|
|
|
|
CP0048192
|
2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol
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|
C24H40O3
|
12
|
| 1 |
EC50 = 0.35 nM
|
|
|
| 2 |
EC50 = 0.88 nM
|
|
|
| 3 |
EC50 = 1.03 nM
|
|
|
| 4 |
EC50 = 9.3 nM
|
|
|
| 5 |
EC50 = 9.4 nM
|
|
|
| 6 |
EC50 = 55 nM
|
|
|
| 7 |
EC50 = 560 nM
|
|
|
| 8 |
IC50 = 1.3 nM
|
|
|
| 9 |
Kd = 0.59 nM
|
|
|
| 10 |
Ki = 0.89 nM
|
|
|
| 11 |
Ki = 1.8 nM
|
|
|
| 12 |
Ki = 8.44 nM
|
|
|
|
CP0569296
|
8-[(6aR,9R,10aR)-1-hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-3-yl]-8-methylnonanenitrile
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|
C26H39NO3
|
1
|
| 1 |
EC50 = 0.38 nM
|
|
|
|
CP0569295
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-[1-(7-isothiocyanatoheptyl)cyclopentyl]-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
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|
C29H43NO3S
|
1
|
| 1 |
EC50 = 0.39 nM
|
|
|
|
CP0410712
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-methyl-1-morpholin-4-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H26F2N4O2
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0050487
|
(11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene
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|
C27H26N2O3
|
4
|
| 1 |
EC50 = 0.47 nM
|
|
|
| 2 |
IC50 = 8.9 nM
|
|
|
| 3 |
Ki = 0.45 nM
|
|
|
| 4 |
Ki = 8.57 nM
|
|
|
|
CP0388577
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluoro-2-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C26H23FN4O2
|
1
|
| 1 |
EC50 = 0.47 nM
|
|
|
|
CP0388674
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-chloroquinolin-3-yl)propanamide
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|
C20H13Cl2FN4O2
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0550412
|
(2R,4R)-9-(2,2-dimethylpropyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H29N3O
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0379014
|
3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(6-chloro-1,8-naphthyridin-3-yl)propanamide
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|
C19H12Cl2FN5O2
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0423249
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide
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|
C25H20ClFN4O2
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0423248
|
N-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C18H18ClFN4O3
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0375333
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-2-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H20F2N4O
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0381508
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopentyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C20H21F2N3O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0410458
|
(2R,4R)-9-(oxan-4-ylmethyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C23H29N3O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0444528
|
3-(2,4-difluorophenyl)-N-(3-tricyclo[3.3.1.03,7]nonanyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
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|
C24H25F2N3O2
|
1
|
| 1 |
EC50 = 0.7 nM
|
|
|
|
CP0570671
|
(6aR,9R,10aR)-3-(8-azido-2-methyloctan-2-yl)-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
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|
C25H39N3O3
|
1
|
| 1 |
EC50 = 0.77 nM
|
|
|
|
CP0437003
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl)propanamide
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|
C18H18ClFN6O2S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0375332
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H21F2N3O
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0375336
|
(2R,4R)-9-(2,5-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0576318
|
7-[1-[(6aR,9R,10aR)-1-hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-3-yl]cyclopentyl]heptanenitrile
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|
C28H41NO3
|
1
|
| 1 |
EC50 = 0.96 nM
|
|
|
|
CP0396917
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R,2R,4S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C24H27F2N3O
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0474275
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclobutyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C19H19F2N3O2
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0410457
|
(2R,4R)-9-[2-(oxan-4-yl)ethyl]-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C24H31N3O2
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0397077
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-phenylcyclopropyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C23H19F2N3O
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0442882
|
N-(1-adamantyl)-4-phenyl-1H-benzimidazole-2-carboxamide
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|
C24H25N3O
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0397078
|
(2R,4R)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0410460
|
(2R,4R)-9-(2-morpholin-4-ylethyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C23H30N4O2
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0437500
|
6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)quinolin-3-amine
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|
C20H15Cl2FN4O
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0568105
|
5-bromo-1-[5-[4-[3-[5-bromo-3-(cycloheptanecarbonylamino)-4-methyl-2-oxopyridin-1-yl]propyl]triazol-1-yl]pentyl]-N-cycloheptyl-6-methyl-2-oxopyridine-3-carboxamide
Show/Hide
|
C38H53Br2N7O4
|
5
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
EC50 = 8 nM
|
|
|
| 3 |
EC50 = 61 nM
|
|
|
| 4 |
EC50 = 73 nM
|
|
|
| 5 |
EC50 > 10000 nM
|
|
|
|
CP0388581
|
N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]-3-(trifluoromethoxy)quinolin-6-amine
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|
C21H15ClF4N4O2
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0388675
|
N-(9-ethylcarbazol-3-yl)-3-[3-(oxan-4-yl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C24H26N4O3
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
|
CP0551146
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-[1-(6-isothiocyanatohexyl)cyclopentyl]-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Show/Hide
|
C28H41NO3S
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0388583
|
N-(2-tert-butylpyrimidin-5-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C19H19ClFN5O2
|
1
|
| 1 |
EC50 = 2.9 nM
|
|
|
|
CP0379970
|
(2S,4S)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H19F2N3O2
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0402406
|
(+)-3-pentyl-4-phenyl-N-((1R,2S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamide
Show/Hide
|
C25H37N3O
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Kd = 0.631 nM
|
|
|
|
CP0397073
|
(2R,4R)-9-(2,4-dichlorophenyl)-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C23H21Cl2N3O
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0379011
|
6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)quinoline
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|
C20H14Cl2FN3O2
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
|
CP0155571
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 = 3.7 nM
|
|
|
|
CP0456396
|
(2R,4R)-N-(2-phenylpropan-2-yl)-9-pyridin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H22N4O
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0379010
|
N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
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|
C25H21FN4O2
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0529528
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-4-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H20F2N4O
|
1
|
| 1 |
EC50 = 5.1 nM
|
|
|
|
CP0474269
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[(1R)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H19F2N3O2
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0396919
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(2-pyridin-3-ylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C22H20F2N4O
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0495408
|
(6aR,9R,10aR)-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyloctan-2-yl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Show/Hide
|
C26H39NO3S
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0481029
|
N-(2,3-dihydroxypropyl)-4-phenyl-1H-benzimidazole-2-carboxamide
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|
C17H17N3O3
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0388576
|
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)propanamide
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|
C19H11ClF4N4O3S
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0381504
|
(2S,4S)-N-tert-butyl-9-(2,4-difluorophenyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0410471
|
(2R,4R)-9-(3-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C18H20FN3O2
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0547254
|
5-bromo-2-[5-[4-[3-[5-bromo-3-(cycloheptanecarbonylamino)-4-methyl-2-oxopyridin-1-yl]propyl]triazol-1-yl]pentoxy]-N-cycloheptyl-6-methylpyridine-3-carboxamide
Show/Hide
|
C38H53Br2N7O4
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0435745
|
N-[(2-chlorophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
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|
C23H20ClN3O
|
1
|
| 1 |
EC50 = 9.9 nM
|
|
|
|
CP0379230
|
(9S)-6,6,9-trimethyl-3-pentyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
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|
C21H30O2
|
2
|
| 1 |
EC50 = 10.9 nM
|
|
|
| 2 |
Ki = 17 nM
|
|
|
|
CP0045801
|
(10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
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|
C21H30O2
|
3
|
| 1 |
EC50 = 12.3 nM
|
|
|
| 2 |
Ki = 46 nM
|
|
|
| 3 |
Ki = 71.6 nM
|
|
|
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CP0483738
|
(2R,4R)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H17F2N3O2
|
1
|
| 1 |
EC50 = 13.6 nM
|
|
|
|
CP0474274
|
(2R,4R)-9-(2,4-dichlorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19Cl2N3O2
|
1
|
| 1 |
EC50 = 14.6 nM
|
|
|
|
CP0443544
|
N-(2,2-dimethylpropyl)-4-phenyl-1H-benzimidazole-2-carboxamide
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|
C19H21N3O
|
1
|
| 1 |
EC50 = 14.7 nM
|
|
|
|
CP0410476
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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|
C19H19F2N3O2
|
1
|
| 1 |
EC50 = 15.2 nM
|
|
|
|
CP0057171
|
3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpiperidin-2-yl)methyl]-1H-indole
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|
C22H22IN3O3
|
2
|
| 1 |
EC50 = 16.4 nM
|
|
|
| 2 |
Ki = 21.8 nM
|
|
|
|
CP0444527
|
3-pyrazin-2-yl-N-(3-tricyclo[3.3.1.03,7]nonanyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
EC50 = 16.6 nM
|
|
|
|
CP0375369
|
(9R)-6,6,9-trimethyl-3-pentyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
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|
C21H30O2
|
2
|
| 1 |
EC50 = 17.4 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0410461
|
(2R,4R)-N-(2-phenylpropan-2-yl)-9-propan-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C20H25N3O
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1
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| 1 |
EC50 = 18.5 nM
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CP0396921
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(2R,4R)-9-(2-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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C18H20FN3O2
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1
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| 1 |
EC50 = 19 nM
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CP0483740
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(2R,4R)-9-(2,4-difluorophenyl)-N-(1-fluoro-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C18H18F3N3O
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1
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| 1 |
EC50 = 19.8 nM
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CP0424563
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5-bromo-N-cycloheptyl-1-[(4-fluorophenyl)methyl]-6-methyl-2-oxopyridine-3-carboxamide
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C21H24BrFN2O2
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2
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| 1 |
EC50 = 20 nM
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| 2 |
EC50 = 63 nM
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CP0396918
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(2R,4R)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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C20H21F2N3O2
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1
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| 1 |
EC50 = 21.2 nM
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CP0397015
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(2R,4R)-N-(2-phenylpropan-2-yl)-9-pyridin-3-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C22H22N4O
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1
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| 1 |
EC50 = 21.9 nM
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CP0560406
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N-(1-adamantyl)-4-(4-fluorobutyl)-7-hydroxy-1-methyl-5-oxo-3a,7a-dihydropyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H31FN4O3
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1
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| 1 |
EC50 = 21.92 nM
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CP0423250
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2-tert-Butyl-5-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)pyrimidine
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C19H20ClFN4O2
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1
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| 1 |
EC50 = 24 nM
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CP0395176
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N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
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C21H23N3O2
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1
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| 1 |
EC50 = 24.6 nM
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CP0397081
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(2S,4S)-9-(2,4-difluorophenyl)-N-[1-(hydroxymethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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C18H17F2N3O2
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1
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| 1 |
EC50 = 24.8 nM
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CP0457650
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3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]propanamide
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C18H11Cl2F4N3O2
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1
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| 1 |
EC50 = 25 nM
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CP0410473
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(2R,4R)-9-(4-fluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C18H20FN3O2
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1
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| 1 |
EC50 = 25.3 nM
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CP0487953
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C16H19N5O2
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1
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| 1 |
EC50 = 25.3 nM
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CP0256129
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naphthalen-1-yl-(4-pentoxynaphthalen-1-yl)methanone
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C26H24O2
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2
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| 1 |
EC50 = 27.9 nM
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| 2 |
IC50 = 98 nM
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CP0388584
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3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-cyano-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)propanamide
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C19H12ClF4N5O3
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1
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| 1 |
EC50 = 31 nM
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CP0423261
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N-(1-adamantyl)-1-pentylpyrrolo[2,3-b]pyridine-3-carboxamide
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C23H31N3O
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1
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| 1 |
EC50 = 32 nM
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CP0456392
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(2R,4R)-9-tert-butyl-N-(2-phenylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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C21H27N3O
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1
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| 1 |
EC50 = 32.9 nM
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CP0388585
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3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-(trifluoromethyl)phenyl)propanamide
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C18H12ClF4N3O2
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1
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| 1 |
EC50 = 38 nM
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CP0379951
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(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C19H19F2N3O2
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1
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| 1 |
EC50 = 38.5 nM
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CP0397080
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(2R,4R)-9-(2,4-difluorophenyl)-N-[(1S)-2-hydroxy-1-phenylethyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
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C22H19F2N3O2
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1
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| 1 |
EC50 = 38.8 nM
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CP0415776
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N-[(3-chlorophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
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C23H20ClN3O
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1
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| 1 |
EC50 = 40 nM
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CP0504793
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2,6-ditert-butyl-4-[2-(4-piperidin-1-yloxan-4-yl)-1,3-thiazol-4-yl]phenol
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C27H40N2O2S
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2
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| 1 |
EC50 = 40 nM
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| 2 |
Ki = 49.7 nM
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CP0401222
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2,6-ditert-butyl-4-[2-[4-(dimethylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
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C24H36N2O2S
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2
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| 1 |
EC50 = 42 nM
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| 2 |
Ki = 29.4 nM
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CP0400313
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C17H20N4O2
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1
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| 1 |
EC50 = 42.4 nM
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CP0434549
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N-[[1-(hydroxymethyl)cyclohexyl]methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
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C22H25N3O2
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1
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| 1 |
EC50 = 43 nM
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CP0415522
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2,6-ditert-butyl-4-[2-[4-(dimethylamino)oxan-4-yl]-1,3-oxazol-4-yl]phenol
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C24H36N2O3
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2
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| 1 |
EC50 = 43.6 nM
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| 2 |
Ki = 51.6 nM
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CP0443542
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1-ethyl-N-[(2-fluorophenyl)methyl]-4-phenylbenzimidazole-2-carboxamide
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C23H20FN3O
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1
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| 1 |
EC50 = 45 nM
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CP0945731
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N-((3s,5s,7s)-Adamantan-1-yl)-1-(2-morpholinoethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
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C24H32N4O2
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1
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| 1 |
EC50 = 48 nM
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CP0547775
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N-(1-bicyclo[2.2.2]octanyl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
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C21H25N5O3
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1
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| 1 |
EC50 = 48.5 nM
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CP0379012
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N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]quinolin-6-amine
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C20H16ClFN4O
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1
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| 1 |
EC50 = 50 nM
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CP0382775
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N-(3-pentyl-1,3-benzothiazol-2-ylidene)adamantane-1-carboxamide
Show/Hide
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C23H30N2OS
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1
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| 1 |
EC50 = 57 nM
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CP0233603
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N-(1-adamantyl)-1-(2-morpholin-4-ylethyl)indazole-3-carboxamide
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C24H32N4O2
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1
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| 1 |
EC50 = 58 nM
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CP0412866
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2,6-ditert-butyl-4-[2-[4-(dimethylamino)thian-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
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C24H36N2OS2
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2
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| 1 |
EC50 = 59.1 nM
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| 2 |
Ki = 81.7 nM
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CP0946442
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N-((3s,5s,7s)-Adamantan-1-yl)-1-(5-hydroxypentyl)-1H-benzo[d]imidazole-2-carboxamide
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C23H31N3O2
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1
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| 1 |
EC50 = 67 nM
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CP0382825
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N-(3-pentyl-1,3-benzothiazol-2-ylidene)naphthalene-1-carboxamide
Show/Hide
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C23H22N2OS
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1
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| 1 |
EC50 = 68 nM
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CP0516606
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4-(4-fluorobutyl)-7-hydroxy-N-(3-hydroxy-1-adamantyl)-1-methyl-5-oxo-3a,7a-dihydropyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H31FN4O4
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1
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| 1 |
EC50 = 71.79 nM
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CP0415520
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2,6-ditert-butyl-4-[2-[4-(diethylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
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C26H40N2O2S
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2
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| 1 |
EC50 = 72 nM
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| 2 |
Ki = 77.4 nM
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CP0381505
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(2S,4S)-9-(2,4-difluorophenyl)-N-(oxan-4-ylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C20H21F2N3O2
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1
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| 1 |
EC50 = 75.6 nM
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CP0379009
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3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethyl)pyridin-3-yl)propanamide
Show/Hide
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C17H11ClF4N4O2
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1
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| 1 |
EC50 = 78 nM
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CP0443545
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N-[(4-cyanophenyl)methyl]-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
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C24H20N4O
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1
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| 1 |
EC50 = 84 nM
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CP0875526
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N-Adamantan-1-yl-1H-indazole-3-carboxamide
Show/Hide
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C18H21N3O
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1
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| 1 |
EC50 = 86 nM
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CP0374913
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5-methoxy-3-[(3-methoxyphenyl)methyl]-7-pentylchromen-2-one
Show/Hide
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C23H26O4
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1
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| 1 |
EC50 = 92 nM
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CP0880785
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N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-indazole-3-carboxamide
Show/Hide
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C23H31N3O
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1
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| 1 |
EC50 = 92 nM
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CP0375335
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-phenyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C18H21N3O2
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1
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| 1 |
EC50 = 100.9 nM
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CP0419762
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N-tert-butyl-3-(2,4-difluorophenyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
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C19H21F2N3O2
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1
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| 1 |
EC50 = 107.5 nM
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CP0516604
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N-(1-adamantyl)-4-butyl-7-hydroxy-1-methyl-5-oxo-3a,7a-dihydropyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H32N4O3
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1
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| 1 |
EC50 = 109.7 nM
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CP0437503
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6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)benzo[d]thiazol-2-amine
Show/Hide
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C18H13Cl2FN4OS
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1
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| 1 |
EC50 = 110 nM
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CP0388582
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5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)isoxazol-3-amine
Show/Hide
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C18H20ClFN4O2
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1
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| 1 |
EC50 = 130 nM
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CP0531513
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5-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene
Show/Hide
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C18H20N6O2S
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1
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| 1 |
EC50 = 130.3 nM
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CP0388568
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N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide
Show/Hide
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C25H21FN4O2
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1
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| 1 |
EC50 = 140 nM
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CP0435746
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N-[(3-chlorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
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C21H16ClN3O
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1
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| 1 |
EC50 = 165 nM
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CP0425247
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methyl 2-(adamantane-1-carbonylamino)-4-ethyl-5-methylthiophene-3-carboxylate
Show/Hide
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C20H27NO3S
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1
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| 1 |
EC50 = 197 nM
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CP0872989
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N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-pyrrolo[3,2-b]-pyridine-2-carboxamide
Show/Hide
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C23H31N3O
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1
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| 1 |
EC50 = 220 nM
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CP0442879
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N-[1-(hydroxymethyl)cyclohexyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
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C21H23N3O2
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1
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| 1 |
EC50 = 236 nM
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CP0560405
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N-(1-adamantyl)-7-hydroxy-1-methyl-5-oxo-4-pentyl-3a,7a-dihydropyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
|
C23H34N4O3
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1
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| 1 |
EC50 = 252.2 nM
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CP0388264
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N-[(2-fluorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
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C21H16FN3O
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1
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| 1 |
EC50 = 256 nM
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CP0481040
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4-phenyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1H-benzimidazole-2-carboxamide
Show/Hide
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C22H16F3N3O
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1
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| 1 |
EC50 = 256 nM
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CP0525855
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N-(1-adamantyl)-4-(4-fluorobutyl)-7-hydroxy-2-methyl-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H29FN4O3
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1
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| 1 |
EC50 = 270 nM
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CP0880751
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N-((3s,5s,7s)-Adamantan-1-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
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C18H21N3O
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1
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| 1 |
EC50 = 290 nM
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CP0462464
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N-(3-pentyl-1,3-benzothiazol-2-ylidene)-3-(trifluoromethyl)benzamide
Show/Hide
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C20H19F3N2OS
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1
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| 1 |
EC50 = 306 nM
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CP0425253
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methyl 2-(adamantane-1-carbonylamino)-4,5-dimethylthiophene-3-carboxylate
Show/Hide
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C19H25NO3S
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1
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| 1 |
EC50 = 318 nM
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CP0875528
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N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-benzo[d]imidazole-2-carboxamide
Show/Hide
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C23H31N3O
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1
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| 1 |
EC50 = 320 nM
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CP0423243
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5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propylamino)-2-(2,2,2-trifluoroethoxy)nicotinonitrile
Show/Hide
|
C19H14ClF4N5O2
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1
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| 1 |
EC50 = 360 nM
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CP0526748
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N-(1-adamantyl)-4-butyl-7-hydroxy-2-methyl-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H30N4O3
|
1
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| 1 |
EC50 = 370 nM
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CP0481802
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methyl 2-(adamantane-1-carbonylamino)-5-ethyl-4-methylthiophene-3-carboxylate
Show/Hide
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C20H27NO3S
|
1
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| 1 |
EC50 = 371 nM
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CP0045030
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(6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6Hdibenzo[b,d]pyran
Show/Hide
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C22H32O
|
1
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| 1 |
EC50 = 391.1 nM
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CP0406642
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrimidin-4-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C16H19N5O2
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1
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| 1 |
EC50 = 420.2 nM
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CP0547777
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(1S,8R)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
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C19H25N5O3
|
1
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| 1 |
EC50 = 422 nM
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CP0442887
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N-[(2-chlorophenyl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
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C21H16ClN3O
|
1
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| 1 |
EC50 = 443 nM
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CP0395175
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N-(2,2-dimethylpropyl)-1-ethyl-4-phenylbenzimidazole-2-carboxamide
Show/Hide
|
C21H25N3O
|
1
|
| 1 |
EC50 = 490 nM
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CP0870429
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N-((3s,5s,7s)-Adamantan-1-yl)-1H-benzo[d]imidazole-2-carboxamide
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
EC50 = 520 nM
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CP0568106
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5-bromo-1-[3-[4-[[5-bromo-3-(cycloheptanecarbonylamino)-4-methyl-2-oxopyridin-1-yl]methyl]triazol-1-yl]propyl]-N-cycloheptyl-6-methyl-2-oxopyridine-3-carboxamide
Show/Hide
|
C34H45Br2N7O4
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2
|
| 1 |
EC50 = 560 nM
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| 2 |
EC50 > 10000 nM
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CP0562120
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3-pyrazin-2-yl-N-[1-(trifluoromethyl)cyclobutyl]-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
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C18H18F3N5O2
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1
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| 1 |
EC50 = 571 nM
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CP0875532
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N-((3s,5s,7s)-Adamantan-1-yl)-1H-pyrrolo[3,2-b]pyridine-2-carboxamide
Show/Hide
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C18H21N3O
|
1
|
| 1 |
EC50 = 590 nM
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CP0531748
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4-(4-fluorobutyl)-7-hydroxy-N-(3-hydroxy-1-adamantyl)-2-methyl-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C22H29FN4O4
|
1
|
| 1 |
EC50 = 590 nM
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CP0516605
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N-(1-adamantyl)-4-butyl-7-hydroxy-1-(2-hydroxyethyl)-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
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C23H32N4O4
|
1
|
| 1 |
EC50 = 628.2 nM
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CP0423239
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N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)tetrazol-2-yl]propanamide
Show/Hide
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C24H21FN6O
|
1
|
| 1 |
EC50 = 690 nM
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CP0379008
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3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butyl)quinoline
Show/Hide
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C21H17ClFN3O
|
1
|
| 1 |
EC50 = 800 nM
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CP0456395
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(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyridin-3-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
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C17H20N4O2
|
1
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| 1 |
EC50 = 809 nM
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CP0375367
|
(6S)-6,9,9-trimethyl-3-pentyl-5,6,7,8-tetrahydroxanthen-1-ol
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C21H30O2
|
2
|
| 1 |
EC50 = 820 nM
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| 2 |
Ki = 180 nM
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CP0564717
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N-(1-adamantyl)-7-hydroxy-2-(2-hydroxyethyl)-5-oxo-4-pentylpyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
|
C24H34N4O4
|
1
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| 1 |
EC50 = 880 nM
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CP0363620
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2-[(4-ethoxyphenyl)methyl]-1-(3-methylbutyl)-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]benzimidazole-5-carboxamide
Show/Hide
|
C39H47N5O2
|
1
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| 1 |
EC50 = 911 nM
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CP0880787
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N-(Adamantan-1-yl)-1-pentyl-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
EC50 = 920 nM
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|
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CP0379220
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(6R)-6,9,9-trimethyl-3-pentyl-5,6,7,8-tetrahydroxanthen-1-ol
Show/Hide
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C21H30O2
|
2
|
| 1 |
EC50 = 930 nM
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| 2 |
Ki = 470 nM
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CP0415775
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N-benzyl-4-phenyl-1H-benzimidazole-2-carboxamide
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C21H17N3O
|
1
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| 1 |
EC50 = 991 nM
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CP0458715
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1-ethyl-4-phenyl-N-(pyrimidin-5-ylmethyl)benzimidazole-2-carboxamide
Show/Hide
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C21H19N5O
|
1
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| 1 |
EC50 = 1104 nM
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CP0386991
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methyl 2-(adamantane-1-carbonylamino)-5-butyl-4-methylthiophene-3-carboxylate
Show/Hide
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C22H31NO3S
|
1
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| 1 |
EC50 = 1135 nM
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|
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CP0516603
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N-(1-adamantyl)-7-hydroxy-2-methyl-5-oxo-4-pentylpyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
|
C23H32N4O3
|
1
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| 1 |
EC50 = 1180 nM
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|
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CP0434550
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1-ethyl-N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenylbenzimidazole-2-carboxamide
Show/Hide
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C23H27N3O2
|
1
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| 1 |
EC50 = 1255 nM
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|
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CP0415774
|
N-[(3-fluoropyridin-2-yl)methyl]-4-phenyl-1H-benzimidazole-2-carboxamide
Show/Hide
|
C20H15FN4O
|
1
|
| 1 |
EC50 = 1437 nM
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|
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CP0516608
|
N-(1-adamantyl)-7-hydroxy-4-(4-hydroxybutyl)-2-methyl-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide
Show/Hide
|
C22H30N4O4
|
1
|
| 1 |
EC50 = 1450 nM
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|
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CP0394005
|
methyl 2-(adamantane-1-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
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C21H27NO3S
|
1
|
| 1 |
EC50 = 1531 nM
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|
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CP0534087
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N-(1-bicyclo[1.1.1]pentanyl)-3-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C18H19N5O3
|
1
|
| 1 |
EC50 = 1781 nM
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|
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CP0443543
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N-[[1-(hydroxymethyl)cyclohexyl]methyl]-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
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C24H26F3N3O2
|
1
|
| 1 |
EC50 = 1973 nM
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|
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CP0870430
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N-((3s,5s,7s)-Adamantan-1-yl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
EC50 = 2000 nM
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|
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CP0525854
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4-[6-(1-adamantylcarbamoyl)-7-hydroxy-2-methyl-5-oxopyrazolo[4,3-b]pyridin-4-yl]butyl acetate
Show/Hide
|
C24H32N4O5
|
1
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| 1 |
EC50 = 2080 nM
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|
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CP0152986
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2-[(4-ethoxyphenyl)methyl]-N,N-diethyl-1-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]benzimidazole-5-carboxamide
Show/Hide
|
C40H49N5O2
|
1
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| 1 |
EC50 = 3050 nM
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|
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CP0044659
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(6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)(4-methoxyphenyl)methanone
Show/Hide
|
C23H25IN2O3
|
1
|
| 1 |
EC50 = 3150 nM
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|
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CP0504361
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5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide
Show/Hide
|
C19H17Cl3N4O2S
|
1
|
| 1 |
EC50 = 7430 nM
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|
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CP0510013
|
1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H20Cl2N4OS
|
1
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| 1 |
EC50 = 7550 nM
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|
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CP0543751
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5-bromo-1-[5-[4-[[5-bromo-3-(cycloheptanecarbonylamino)-4-methyl-2-oxopyridin-1-yl]methyl]triazol-1-yl]pentyl]-N-cycloheptyl-6-methyl-2-oxopyridine-3-carboxamide
Show/Hide
|
C36H49Br2N7O4
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0233896
|
N-[5-bromo-1-[(4-fluorophenyl)methyl]-4-methyl-2-oxopyridin-3-yl]cycloheptanecarboxamide
Show/Hide
|
C21H24BrFN2O2
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0568259
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5-bromo-1-[3-[4-[3-[5-bromo-3-(cycloheptanecarbonylamino)-4-methyl-2-oxopyridin-1-yl]propyl]triazol-1-yl]propyl]-N-cycloheptyl-6-methyl-2-oxopyridine-3-carboxamide
Show/Hide
|
C36H49Br2N7O4
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0375107
|
N-(azepan-1-yl)-5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C21H21Cl3N4OS
|
1
|
| 1 |
EC50 = 12810 nM
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|
|
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CP0372216
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5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-4-methyl-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H21Cl3N4OS
|
1
|
| 1 |
EC50 = 15660 nM
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|
|
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CP0388262
|
N-(2,2-dimethylpropyl)-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
|
C21H22F3N3O
|
1
|
| 1 |
EC50 > 17000 nM
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|
|
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CP0484632
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N-[[1-(hydroxymethyl)cyclopentyl]methyl]-4-phenyl-1-(2,2,2-trifluoroethyl)benzimidazole-2-carboxamide
Show/Hide
|
C23H24F3N3O2
|
1
|
| 1 |
EC50 > 17000 nM
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|
|
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CP0372215
|
5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C21H21BrCl2N4OS
|
1
|
| 1 |
EC50 = 19540 nM
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|
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CP0372217
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5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(pyrrolidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C19H17Cl3N4OS
|
1
|
| 1 |
EC50 = 20920 nM
|
|
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CP0396920
|
(2R,4R)-9-(2,6-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 = 23000 nM
|
|
|
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CP0462567
|
5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19BrCl2N4OS
|
1
|
| 1 |
EC50 = 23210 nM
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|
|
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CP0373856
|
5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19Cl3N4OS
|
1
|
| 1 |
EC50 = 23670 nM
|
|
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CP0375422
|
5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C21H21Cl3N4OS
|
1
|
| 1 |
EC50 = 25930 nM
|
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CP0152977
|
5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1H-pyrazole-3-carboxylic acid ((1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide
Show/Hide
|
C29H34ClN3O
|
1
|
| 1 |
EC50 = 26690 nM
|
|
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CP0504362
|
1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C20H19Cl2IN4OS
|
1
|
| 1 |
EC50 = 29440 nM
|
|
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CP0003146
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5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H21Cl3N4O
|
5
|
| 1 |
EC50 = 31210 nM
|
|
|
| 2 |
IC50 = 1760 nM
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|
|
| 3 |
IC50 > 1000 nM
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|
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| 4 |
Ki = 313 nM
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| 5 |
Ki = 522 nM
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CP0423247
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3-(3-(3-Cyanopyridin-4-yl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9Hcarbazol-3-yl)propanamide
Show/Hide
|
C25H20N6O2
|
1
|
| 1 |
EC50 > 2.6 nM
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|
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CP0419763
|
N-tert-butyl-4-pyrazin-2-yl-11-oxa-4,5-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-3-carboxamide
Show/Hide
|
C17H21N5O2
|
1
|
| 1 |
EC50 > 5 nM
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|
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CP0512425
|
N-tert-butyl-4-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-5-carboxamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
EC50 > 5 nM
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|
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CP0514913
|
N-tert-butyl-4-(2,4-difluorophenyl)-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-5-carboxamide
Show/Hide
|
C19H21F2N3O2
|
1
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| 1 |
EC50 > 5 nM
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|
|
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CP0547773
|
N-tert-butyl-4-(4-oxidopyrazin-4-ium-2-yl)-11-oxa-4,5-diazatricyclo[6.2.1.02,6]undeca-2,5-diene-3-carboxamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
EC50 > 5 nM
|
|
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CP0547774
|
(1R,8S)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene-5-carboxamide
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
EC50 > 5 nM
|
|
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CP0547776
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5-[3-(2-methylbutan-2-yl)-1,2,4-oxadiazol-5-yl]-3-pyrazin-2-yl-11-oxa-3,4-diazatricyclo[6.2.1.02,6]undeca-2(6),4-diene
Show/Hide
|
C19H22N6O2
|
1
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| 1 |
EC50 > 5 nM
|
|
|
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CP0438981
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-chlorophenyl)methanone
Show/Hide
|
C22H24ClNO2
|
1
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| 1 |
IC50 = 0.14 nM
|
|
|
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CP0456333
|
(2,3-dichlorophenyl)(1-((4,4-difluoropiperidin-1-yl)methyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
|
C20H17Cl2F2N3O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
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CP0478652
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-6-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
|
| 1 |
IC50 = 0.53 nM
|
|
|
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CP0478744
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-4-yl)methanone
Show/Hide
|
C24H26N2O2
|
1
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| 1 |
IC50 = 0.62 nM
|
|
|
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CP0456331
|
(3-fluoro-2-(trifluoromethyl)phenyl)(1-(morpholinomethyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
|
C20H17F4N3O2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
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CP0473967
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[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
|
| 1 |
IC50 = 0.82 nM
|
|
|
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CP0442074
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-5-yl)methanone
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
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CP0422123
|
1-((4,4-difluoropiperidin-1-yl)methyl)-N-(6-(trifluoromethyl)pyridin-2-yl)imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C20H18F5N5O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
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CP0486873
|
3-((4,4-difluoropiperidin-1-yl)methyl)-N-((1-(hydroxymethyl)cyclopentyl)methyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C21H28F2N4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0442065
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-3-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
|
| 1 |
IC50 = 3.38 nM
|
|
|
|
CP0442076
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indazol-4-yl)methanone
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0438979
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0396093
|
N-(1-adamantyl)-1-[hydroxy(pyridin-3-yl)methyl]imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0456330
|
(2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1,5-a]pyridin-3-yl)methanone
Show/Hide
|
C19H17Cl2N3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0510176
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,6-naphthyridin-2-yl)methanone
Show/Hide
|
C24H25N3O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0465455
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpyrrolidin-3-yl)methanone
Show/Hide
|
C21H30N2O2
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0438982
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(6-methylpyridin-2-yl)methanone
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0442078
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(3-fluoropyridin-4-yl)methanone
Show/Hide
|
C21H23FN2O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0494387
|
3-cyclopropyl-N-(dicyclopropylmethyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0504257
|
1-(4-Chloro-benzyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid adamantan-2-ylamide
Show/Hide
|
C29H31ClN2O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0460404
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,2-oxazol-3-yl)methanone
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0438986
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[6-(trifluoromethyl)pyridin-3-yl]methanone
Show/Hide
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C22H23F3N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0473931
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(6-cyclopropylpyridin-3-yl)methanone
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0921023
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-pyrrolo[3,2-b]-pyridine-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0436298
|
((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)((S)-4-methylmorpholin-3-yl)methanone
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0473916
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]methanone
Show/Hide
|
C23H25F3N2O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
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CP0456332
|
3-cyclopropyl-N-neopentylimidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
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CP0465939
|
(R)-3-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-yl)ethyl)imidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C19H18F3N5O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
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CP0504979
|
[(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[3-(2-fluorophenyl)-1H-pyrazol-5-yl]methanone
Show/Hide
|
C25H26FN3O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0465459
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-indol-4-yl)methanone
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0494384
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-chlorophenyl)methanone
Show/Hide
|
C22H24ClNO2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0491384
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[1-(2,2,2-trifluoroethyl)imidazol-4-yl]methanone
Show/Hide
|
C21H24F3N3O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0321142
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)cyclobutyl)-1,3,4-thiadiazole
Show/Hide
|
C26H18BrF6N7S
|
1
|
| 1 |
IC50 = 27.6 nM
|
|
|
|
CP0494383
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-pyrimidin-2-ylmethanone
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0436297
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[4-(2,2,2-trifluoroethyl)morpholin-2-yl]methanone
Show/Hide
|
C22H29F3N2O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0478648
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(4-methylmorpholin-3-yl)methanone
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0436035
|
N-[[1-(hydroxymethyl)cyclopentyl]methyl]-3-morpholin-4-ylimidazo[1,5-a]pyridine-1-carboxamide
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0442067
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-benzimidazol-4-yl)methanone
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0486872
|
(R)-1-(4,4-difluoropiperidin-1-yl)-N-(3,3-dimethylbutan-2-yl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H25F2N5O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0891222
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazole-2-carboxamide
Show/Hide
|
C24H32N4O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0473678
|
(4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone
Show/Hide
|
C25H21ClN2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0473965
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone
Show/Hide
|
C25H26N2O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0491382
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,3-thiazol-4-yl)methanone
Show/Hide
|
C19H22N2O2S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0482152
|
1-[(1,1-dioxidothiomorpholin-4-yl)methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]imidazo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C19H18F3N5O3S
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0478651
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0462994
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpiperidin-2-yl)methanone
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0494386
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-piperazin-2-ylmethanone
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0467665
|
1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-3-yl)ethyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H17F3N6O2
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0287698
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)-cyclobutyl)-1,3,4-thiadiazole
Show/Hide
|
C25H18BrClF3N7S
|
1
|
| 1 |
IC50 = 73.6 nM
|
|
|
|
CP0315157
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2-(trifluoromethyl)phenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethylcyclobutyl)-1,3,4-thiadiazole
Show/Hide
|
C26H18ClF6N7S
|
1
|
| 1 |
IC50 = 76.8 nM
|
|
|
|
CP0921020
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-(2-morpholinoethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C24H32N4O2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0434158
|
(4-butoxynaphthalen-1-yl)-naphthalen-1-ylmethanone
Show/Hide
|
C25H22O2
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0372383
|
naphthalen-1-yl-(4-propoxynaphthalen-1-yl)methanone
Show/Hide
|
C24H20O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0422830
|
1-(3,3-difluoropyrrolidin-1-yl)-N-((4-fluorophenyl)(pyridin-4-yl)methyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C23H19F3N6O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0465456
|
[(4R,4aS,8aS)-4-hydroxy-4-(4-methylsulfonylphenyl)-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C23H27NO4S
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0400951
|
N-(1-adamantyl)-2,5-dimethyl-1-phenylpyrrole-3-carboxamide
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
IC50 = 108.6 nM
|
|
|
|
CP0435955
|
naphthalen-1-yl-[4-(pentylamino)naphthalen-1-yl]methanone
Show/Hide
|
C26H25NO
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0476227
|
4-Bromo-1-(4-chloro-benzyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid adamantan-2-ylamide
Show/Hide
|
C29H30BrClN2O
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0040713
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)cyclopropyl)-1,3,4-thiadiazole
Show/Hide
|
C24H16BrClF3N7S
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0436295
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylimidazol-2-yl)methanone
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0507677
|
5-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]-1-methylpiperidin-2-one
Show/Hide
|
C22H30N2O3
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0467664
|
(R)-1-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-yl)ethyl)imidazo[1,5-a]pyrazine-3-carboxamide
Show/Hide
|
C18H17F3N6O2
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0491383
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0501617
|
[(4R,4aS,8aS)-4-(4-chlorophenyl)-4-hydroxy-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H24ClNO2
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
|
CP0478657
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1,3-oxazol-5-yl)methanone
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0460407
|
5-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]pyrrolidin-2-one
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0322858
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-phenylcyclopropyl)-1,3,4-oxadiazole
Show/Hide
|
C29H20BrCl2N7O
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0510472
|
2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)cyclopropyl)-1,3,4-oxadiazole
Show/Hide
|
C24H14BrCl2F3N6OS
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0880786
|
N-((3s,5s,7s)-Adamantan-1-yl)-1-pentyl-1H-pyrrolo[3,2-c]-pyridine-3-carboxamide
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0329795
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazol-3-yl)-5-(1-(4-chlorophenyl)-cyclopropyl)-1,3,4-thiadiazole
Show/Hide
|
C29H20Cl3N7S
|
1
|
| 1 |
IC50 = 265 nM
|
|
|
|
CP0473933
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1H-1,2,4-triazol-5-yl)methanone
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
IC50 = 282 nM
|
|
|
|
CP0470897
|
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)(4-(3-chlorophenyl)piperazin-1-yl)methanone
Show/Hide
|
C29H24BrCl2N7O
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0491380
|
[(4R,4aS,8aS)-4-hydroxy-4-(3-methylsulfonylphenyl)-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C23H27NO4S
|
1
|
| 1 |
IC50 = 338 nM
|
|
|
|
CP0465457
|
[(4R,4aS,8aS)-4-hydroxy-4-(4-methoxyphenyl)-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C23H27NO3
|
1
|
| 1 |
IC50 = 358 nM
|
|
|
|
CP0506456
|
5-(4-bromophenyl)-3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-(2,4-dichlorophenyl)-N-(pyridin-2-yl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C27H21BrCl2N6O2
|
1
|
| 1 |
IC50 = 374 nM
|
|
|
|
CP0219934
|
2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methoxymethyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
|
C23H21Cl3N4O2
|
1
|
| 1 |
IC50 = 375 nM
|
|
|
|
CP0257078
|
2-(4-((1H-Imidazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
Show/Hide
|
C25H21Cl3N6O
|
1
|
| 1 |
IC50 = 376 nM
|
|
|
|
CP0481501
|
5-(4-bromophenyl)-3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-1-(2,4-dichlorophenyl)-N-phenyl-1H-pyrazole-4-carboxamide
Show/Hide
|
C28H22BrCl2N5O2
|
1
|
| 1 |
IC50 = 386 nM
|
|
|
|
CP0465453
|
[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpiperidin-4-yl)methanone
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
IC50 = 395 nM
|
|
|
|
CP0856485
|
2-Ethyl-5-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid adamantan-1-ylamide
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
IC50 = 398.3 nM
|
|
|
|
CP0310594
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-methylcyclopropyl)-1,3,4-oxadiazole
Show/Hide
|
C24H18BrCl2N7O
|
1
|
| 1 |
IC50 = 407 nM
|
|
|
|
CP0499150
|
2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-methyl-1,3,4-oxadiazol-2-yl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
Show/Hide
|
C24H19BrCl2N6O2
|
1
|
| 1 |
IC50 = 414 nM
|
|
|
|
CP0475262
|
1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid bicyclo[2.2.1]heptan-2-ylamide
Show/Hide
|
C26H27ClN2O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0510473
|
2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
Show/Hide
|
C24H19BrCl2N6S2
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0047416
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
Show/Hide
|
C24H20BrCl2N7S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0385072
|
ethyl 2-(adamantane-1-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C22H29NO3S
|
1
|
| 1 |
IC50 = 474.9 nM
|
|
|
|
CP0526175
|
5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-N-phenyl-3-(5-(1-(trifluoromethyl)cyclopropyl)-1,3,4-oxadiazol-2-yl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C28H17BrCl2F3N5O2
|
1
|
| 1 |
IC50 = 488 nM
|
|
|
|
CP0473968
|
[(4R,4aS,8aS)-4-(3-chlorophenyl)-4-hydroxy-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
|
C22H24ClNO2
|
1
|
| 1 |
IC50 = 493 nM
|
|
|
|
CP0428629
|
(1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone
Show/Hide
|
C25H20ClNO
|
1
|
| 1 |
IC50 = 498 nM
|
|
|
|
CP0277930
|
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)-cyclobutyl)-1,3,4-thiadiazole
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C25H17Cl3F3N7S
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1
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| 1 |
IC50 = 505 nM
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CP0123663
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
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C24H20BrCl2N7O
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1
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| 1 |
IC50 = 513 nM
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CP0310177
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2-(3-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)acetonitrile
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C23H18Cl3N5O
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1
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| 1 |
IC50 = 539 nM
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CP0524313
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(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)(4-(2,3-dimethylphenyl)piperazin-1-yl)methanone
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C31H29BrClN7O
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1
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| 1 |
IC50 = 547 nM
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CP0047412
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
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C24H21BrClN7S
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1
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| 1 |
IC50 = 549 nM
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CP0439362
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-p-tolylcyclopropyl)-1,3,4-oxadiazole
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C30H22BrCl2N7O
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1
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| 1 |
IC50 = 579 nM
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CP0372029
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(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)(4-(2,3-dichlorophenyl)piperazin-1-yl)methanone
Show/Hide
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C29H23BrCl3N7O
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1
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| 1 |
IC50 = 582 nM
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CP0493483
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3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-(pyridin-2-yl)-1H-pyrazole-4-carboxamide
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C27H21Cl3N6O2
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1
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| 1 |
IC50 = 636 nM
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CP0451682
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(4-hexyloxynaphthalen-1-yl)naphthalen-1-ylmethanone
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C27H26O2
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1
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| 1 |
IC50 = 660 nM
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CP0333797
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2-(4-((2H-tetrazol-2-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
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C23H19Cl3N8O
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1
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| 1 |
IC50 = 680 nM
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CP0288256
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2-(4-((1H-Tetrazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
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C23H19Cl3N8O
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1
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| 1 |
IC50 = 736 nM
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CP0529419
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3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-phenyl-1H-pyrazole-4-carboxamide
Show/Hide
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C28H22Cl3N5O2
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1
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| 1 |
IC50 = 738 nM
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CP0123664
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
Show/Hide
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C24H20Cl3N7O
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1
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| 1 |
IC50 = 804 nM
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CP0491381
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[(4R,4aS,8aS)-4-hydroxy-4-[3-(trifluoromethyl)phenyl]-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
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C23H24F3NO2
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1
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| 1 |
IC50 = 810 nM
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CP0310178
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(1-fluoroethyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C23H20Cl3FN4O
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1
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| 1 |
IC50 = 924 nM
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CP0442064
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[(4R,4aS,8aS)-4-hydroxy-4-pyridin-3-yl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
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C21H24N2O2
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1
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| 1 |
IC50 = 938 nM
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CP0423102
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)cyclopropyl)-1,3,4-oxadiazole
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C24H15BrCl2F3N7O
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1
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| 1 |
IC50 = 948 nM
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CP0212268
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-methylcyclopropyl)-1,3,4-oxadiazole
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C24H18Cl3N7O
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1
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| 1 |
IC50 = 954 nM
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CP0123666
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2-(4-((1H-Pyrazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
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C25H21Cl3N6O
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1
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| 1 |
IC50 = 979 nM
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CP0465460
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3-[(4R,4aS,8aS)-1-benzoyl-4-hydroxy-2,3,4a,5,6,7,8,8a-octahydroquinolin-4-yl]benzonitrile
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C23H24N2O2
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1
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| 1 |
IC50 = 1045 nM
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CP0219933
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-vinyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole
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C23H19Cl3N4O
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1
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| 1 |
IC50 = 1050 nM
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CP0310172
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(4-chlorophenyl)cyclopropyl)-1,3,4-oxadiazole
Show/Hide
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C29H19BrCl3N7O
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1
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| 1 |
IC50 = 1050 nM
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CP0123671
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(fluoromethyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C22H18Cl3FN4O
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1
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| 1 |
IC50 = 1120 nM
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CP0322859
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2-(4-((1H-1,2,3-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-oxadiazole
Show/Hide
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C24H20Cl3N7O
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1
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| 1 |
IC50 = 1120 nM
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CP0531888
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-phenylcyclopropyl)-1,3,4-oxadiazole
Show/Hide
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C29H20Cl3N7O
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1
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| 1 |
IC50 = 1130 nM
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CP0335834
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
Show/Hide
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C24H20Cl3N7S
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1
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| 1 |
IC50 = 1140 nM
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CP0106737
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N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]oxypropanamide
Show/Hide
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C27H25ClF3N3O2
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1
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| 1 |
IC50 = 1170 nM
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CP0529526
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-p-tolylcyclopropyl)-1,3,4-oxadiazole
Show/Hide
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C30H22Cl3N7O
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1
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| 1 |
IC50 = 1240 nM
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CP0465454
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[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[3-(2-fluorophenyl)-1H-pyrazol-5-yl]methanone
Show/Hide
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C25H26FN3O2
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1
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| 1 |
IC50 = 1286 nM
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CP0310595
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(3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)methyl acetate
Show/Hide
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C24H21Cl3N4O3
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1
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| 1 |
IC50 = 1300 nM
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CP0436296
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[(4R,4aS,8aS)-4-hydroxy-4-pyridin-2-yl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-phenylmethanone
Show/Hide
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C21H24N2O2
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1
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| 1 |
IC50 = 1357 nM
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CP0293932
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2-tert-butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C22H19Cl3N4O
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1
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| 1 |
IC50 = 1410 nM
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CP0219932
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S-[[3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)pyrazol-4-yl]methyl] ethanethioate
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C24H21Cl3N4O2S
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1
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| 1 |
IC50 = 1480 nM
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CP0310173
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(4-chlorophenyl)cyclopropyl)-1,3,4-oxadiazole
Show/Hide
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C29H19Cl4N7O
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1
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| 1 |
IC50 = 1480 nM
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CP0288258
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2-(3-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)propan-2-ol
Show/Hide
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C24H23Cl3N4O2
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1
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| 1 |
IC50 = 1670 nM
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CP0293931
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methyl N-[[3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)pyrazol-4-yl]methyl]carbamate
Show/Hide
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C24H22Cl3N5O3
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1
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| 1 |
IC50 = 1670 nM
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CP0123668
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(prop-1-en-2-yl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C24H21Cl3N4O
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1
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| 1 |
IC50 = 1730 nM
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CP0353066
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl)cyclopropyl)-1,3,4-oxadiazole
Show/Hide
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C24H15Cl3F3N7O
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1
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| 1 |
IC50 = 1750 nM
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CP0492814
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-N-(1-(4-bromophenyl)ethyl)-1-(2-chlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H21Br2ClN6O
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1
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| 1 |
IC50 = 1790 nM
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CP0123672
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(3-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)methanol
Show/Hide
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C22H19Cl3N4O2
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1
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| 1 |
IC50 = 1810 nM
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CP0322861
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1-(3-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-4-yl)ethanol
Show/Hide
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C23H21Cl3N4O2
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1
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| 1 |
IC50 = 1890 nM
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CP0445802
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naphthalen-1-yl-[4-(2-phenylethoxy)naphthalen-1-yl]methanone
Show/Hide
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C29H22O2
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1
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| 1 |
IC50 = 2000 nM
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CP0298917
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-((pyridin-2-yloxy)methyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C27H22Cl3N5O2
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1
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| 1 |
IC50 = 2040 nM
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CP0473934
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[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-[(2S,4S)-4-hydroxypiperidin-2-yl]methanone
Show/Hide
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C21H30N2O3
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1
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| 1 |
IC50 = 2175 nM
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CP0322862
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C23H21Cl3N4O
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1
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| 1 |
IC50 = 2330 nM
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CP0866740
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5-[2-Chloro-5-(trifluoromethyl)phenyl]-6-(cyclopentyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
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C24H26ClF3N2O3
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1
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| 1 |
IC50 = 2390 nM
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CP0506308
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-N-(1-(2,4-dichlorophenyl)ethyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H20BrCl3N6O
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1
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| 1 |
IC50 = 2420 nM
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CP0372032
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-N-(1-(4-chlorophenyl)cyclopropyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C28H21BrCl2N6O
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1
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| 1 |
IC50 = 2570 nM
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CP0212269
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-isopropyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C24H23Cl3N4O
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1
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| 1 |
IC50 = 2820 nM
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CP0513908
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-N-(1-phenylcyclopropyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C28H22BrClN6O
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1
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| 1 |
IC50 = 3200 nM
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CP0310596
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2-tert-Butyl-5-(5-(4-chlorophenyl)-4-cyclopropyl-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C24H21Cl3N4O
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1
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| 1 |
IC50 = 3320 nM
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CP0430447
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4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-N-(1-(2,4-dichlorophenyl)ethyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H20Cl4N6O
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1
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| 1 |
IC50 = 3330 nM
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CP0442069
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4-[(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinoline-1-carbonyl]pyrrolidin-2-one
Show/Hide
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C20H26N2O3
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1
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| 1 |
IC50 = 3471 nM
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CP0373556
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4-((1H-1,2,4-Triazol-1-yl)methyl)-N-(1-(4-bromophenyl)ethyl)-1-(2-chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H21BrCl2N6O
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1
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| 1 |
IC50 = 3510 nM
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CP0277684
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2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-(1-(trifluoromethyl-)cyclopropyl)-1,3,4-thiadiazole
Show/Hide
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C24H15Cl3F3N7S
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1
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| 1 |
IC50 = 3631 nM
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CP0491179
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-N-cyclohexyl-1H-pyrazole-3-carboxamide
Show/Hide
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C25H24BrClN6O
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1
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| 1 |
IC50 = 4060 nM
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CP0398999
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N-tert-butyl-4-[(2-chlorophenyl)-(4-chlorophenyl)methyl]piperazine-1-carboxamide
Show/Hide
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C22H27Cl2N3O
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1
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| 1 |
IC50 = 4820 nM
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CP0379057
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4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-tert-butylpiperazine-1-carboxamide
Show/Hide
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C22H27BrClN3O
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1
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| 1 |
IC50 = 4950 nM
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CP0257079
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-(phenoxymethyl)-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C28H23Cl3N4O2
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1
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| 1 |
IC50 = 5910 nM
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CP0426990
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4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-N-(1-(4-bromophenyl)ethyl)-1-(2,4-dichlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
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C27H20Br2Cl2N6O
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1
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| 1 |
IC50 = 6480 nM
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CP0880752
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N-((3s,5s,7s)-Adamantan-1-yl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
Show/Hide
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C18H21N3O
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1
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| 1 |
IC50 = 6500 nM
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CP0219937
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2-tert-Butyl-5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-propyl-1H-pyrazol-3-yl)-1,3,4-oxadiazole
Show/Hide
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C24H23Cl3N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0541700
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methyl N-[1-[3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)pyrazol-4-yl]ethyl]carbamate
Show/Hide
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C25H24Cl3N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0506457
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5-(4-bromophenyl)-3-(5-(1-(4-chlorophenyl)cyclopropyl)-1,3,4-oxadiazol-2-yl)-1-(2,4-dichlorophenyl)-N-phenyl-1H-pyrazole-4-carboxamide
Show/Hide
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C33H21BrCl3N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0401421
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2-(5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrazol-3-yl)-5-(1-(4-chlorophenyl)cyclopropyl)-1,3,4-thiadiazole
Show/Hide
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C29H18BrCl3N6S2
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1
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| 1 |
IC50 > 10000 nM
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CP0372422
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4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
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C25H31Cl2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
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|
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CP0372423
|
4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
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C25H31BrClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0372424
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N-tert-butyl-4-[(4-chlorophenyl)-(2-methylphenyl)methyl]piperazine-1-carboxamide
Show/Hide
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C23H30ClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0372425
|
4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C25H32ClN3O
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
|
CP0379058
|
4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
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C24H28Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398998
|
4-((4-Chlorophenyl)(o-tolyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
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C26H34ClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0399000
|
4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
|
C24H28Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0399001
|
4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401145
|
4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401169
|
4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C26H31ClF3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0458884
|
4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C25H31Cl2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459965
|
4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-(cyclohexylmethyl)piperazine-1-carboxamide
Show/Hide
|
C26H31ClF3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459966
|
4-((4-Bromophenyl)(2-chlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C25H31BrClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0459967
|
4-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)-methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
|
C25H29ClF3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0484630
|
4-((2-Chlorophenyl)(4-chlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide
Show/Hide
|
C24H29Cl2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491312
|
4-((4-Chlorophenyl)(o-tolyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C26H34ClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528485
|
4-((4-Bromophenyl)(2-chlorophenyl)methyl)-Ncyclohexylpiperazine-1-carboxamide
Show/Hide
|
C24H29BrClN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0535141
|
N-tert-butyl-4-[(4-chlorophenyl)-(2,3-dichlorophenyl)methyl]piperazine-1-carboxamide
Show/Hide
|
C22H26Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0566990
|
4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cycloheptylpiperazine-1-carboxamide
Show/Hide
|
C25H30Cl3N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0378554
|
[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]-naphthalen-1-ylmethanone
Show/Hide
|
C27H25NO3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0494385
|
[(4R,4aS,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(1-methylpyrrolidin-3-yl)methanone
Show/Hide
|
C21H30N2O2
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0444845
|
(4-amino-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone
Show/Hide
|
C18H16N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0476226
|
1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid piperidin-1-ylamide
Show/Hide
|
C24H26ClN3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0911978
|
5-(2-chloro-5-(trifluoromethyl)phenyl)-1-(cyclohexylmethyl)-N-((1R,2R)-2-hydroxycyclohexyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C26H32ClF3N2O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0287055
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-(thiophen-2-yl)propan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C23H28O2S
|
1
|
| 1 |
Ki = 0.27 nM
|
|
|
|
CP0257214
|
(6aR,10aR)-3-(2-(3-bromophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29BrO2
|
1
|
| 1 |
Ki = 0.54 nM
|
|
|
|
CP0157108
|
(6aR,10aR)-3-(2-(4-ethylphenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C27H34O2
|
1
|
| 1 |
Ki = 0.67 nM
|
|
|
|
CP0399623
|
N-(1-adamantyl)-1-(2-ethoxyethyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0399621
|
1-(2-ethoxyethyl)-N-(3-hydroxy-1-adamantyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O5
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0272343
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-p-tolylpropan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C26H32O2
|
1
|
| 1 |
Ki = 0.88 nM
|
|
|
|
CP0253788
|
(6aR,10aR)-3-(2-(3-fluorophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29FO2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0042459
|
(6aR,10aR)-6,6,9-Trimethyl-3-(1-methyl-1-phenyl-ethyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H30O2
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0337138
|
3-(2-((6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-3-yl)propan-2-yl)benzonitrile
Show/Hide
|
C26H29NO2
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
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CP0286060
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-m-tolylpropan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C26H32O2
|
1
|
| 1 |
Ki = 1.13 nM
|
|
|
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CP0286058
|
(6aR,10aR)-3-(2-(4-bromophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29BrO2
|
1
|
| 1 |
Ki = 1.54 nM
|
|
|
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CP0353026
|
(6aR,10aR)-3-(2-(4-chlorophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29ClO2
|
1
|
| 1 |
Ki = 1.68 nM
|
|
|
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CP0480579
|
N-(1-adamantyl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide
Show/Hide
|
C26H34N2O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
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CP0257213
|
3-[1-(4-Cyano-phenyl)-1-methyl-ethyl]-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C26H29NO2
|
1
|
| 1 |
Ki = 2.53 nM
|
|
|
|
CP0472351
|
N-(1-adamantyl)-1-butyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0333956
|
(6aR,10aR)-3-(2-(3-chlorophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29ClO2
|
1
|
| 1 |
Ki = 3.54 nM
|
|
|
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CP0139483
|
(6aR,10aR)-3-(2-(3,5-dimethylphenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C27H34O2
|
1
|
| 1 |
Ki = 7.45 nM
|
|
|
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CP0157114
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-(4-propylphenyl)propan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C28H36O2
|
1
|
| 1 |
Ki = 7.83 nM
|
|
|
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CP0472350
|
N-tert-butyl-1-butyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C19H26N2O3
|
1
|
| 1 |
Ki = 8.2 nM
|
|
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CP0124848
|
(6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-6,6-dimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H38O3
|
1
|
| 1 |
Ki = 9.78 nM
|
|
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CP0302795
|
(6aR,10aR)-6,6,9-trimethyl-3-(2-o-tolylpropan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C26H32O2
|
1
|
| 1 |
Ki = 10.65 nM
|
|
|
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CP0157111
|
(6aR,10aR)-3-(2-(4-fluorophenyl)propan-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C25H29FO2
|
1
|
| 1 |
Ki = 12.4 nM
|
|
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CP0493669
|
4-[2-[(6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]propan-2-yl]benzamide
Show/Hide
|
C26H31NO3
|
1
|
| 1 |
Ki = 13.6 nM
|
|
|
|
CP0858762
|
tert-Butyl(2Z)-2-(1-hexyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinecarboxylate
Show/Hide
|
C19H27N3O3
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
|
CP0870663
|
N'-(1-benzyl-2-oxoindolin-3-ylidene)benzohydrazide
Show/Hide
|
C22H17N3O2
|
1
|
| 1 |
Ki = 18.5 nM
|
|
|
|
CP0893315
|
N-[(3Z)-1-(1-Butyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide
Show/Hide
|
C19H19N3O2
|
1
|
| 1 |
Ki = 19.3 nM
|
|
|
|
CP0476825
|
1-butyl-N-cyclopentyl-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C20H26N2O3
|
1
|
| 1 |
Ki = 19.7 nM
|
|
|
|
CP0037364
|
(-)-(6aR-trans)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol
Show/Hide
|
C21H30O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0877296
|
3-[5-(2-Bromo-4-fluorophenyl)-1,3,4-oxadiazol-2-yl]-N-[9-(2-fluoroethyl)-9H-carbazol-3-yl]propanamide
Show/Hide
|
C25H19BrF2N4O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0428941
|
N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]methanesulfonamide
Show/Hide
|
C29H27Cl3N4O3S
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0467628
|
N-(1-hexyl-2-hydroxyindol-3-yl)iminobenzamide
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
Ki = 44.3 nM
|
|
|
|
CP0437502
|
N-[1-(2-cyclohexylethyl)-2-hydroxyindol-3-yl]iminobenzamide
Show/Hide
|
C23H25N3O2
|
1
|
| 1 |
Ki = 58.8 nM
|
|
|
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CP0385624
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclopentanecarboxamide
Show/Hide
|
C28H28Cl2N6O
|
1
|
| 1 |
Ki = 60.2 nM
|
|
|
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CP0561027
|
1-butyl-N-(cyclopropylmethyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C19H24N2O3
|
1
|
| 1 |
Ki = 78.8 nM
|
|
|
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CP0385620
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-3-methylbutanamide
Show/Hide
|
C27H28Cl2N6O
|
1
|
| 1 |
Ki = 89.5 nM
|
|
|
|
CP0771480
|
N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
Ki = 89.9 nM
|
|
|
|
CP0489824
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-cyclohexylpiperazin-1-yl)purine
Show/Hide
|
C27H28Cl2N6
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0431624
|
4-[4-(3,5-ditert-butylphenyl)-1,3-thiazol-2-yl]-N,N-dimethyloxan-4-amine
Show/Hide
|
C24H36N2OS
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0433639
|
2,6-ditert-butyl-4-[2-[4-(methylamino)oxan-4-yl]-1,3-thiazol-4-yl]phenol
Show/Hide
|
C23H34N2O2S
|
1
|
| 1 |
Ki = 144 nM
|
|
|
|
CP0486959
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-propylurea
Show/Hide
|
C26H27Cl2N7O
|
1
|
| 1 |
Ki = 153 nM
|
|
|
|
CP0401221
|
2,6-ditert-butyl-4-[2-(4-morpholin-4-yloxan-4-yl)-1,3-thiazol-4-yl]phenol
Show/Hide
|
C26H38N2O3S
|
1
|
| 1 |
Ki = 177 nM
|
|
|
|
CP0410195
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-ethylurea
Show/Hide
|
C31H30Cl3N5O2
|
1
|
| 1 |
Ki = 182 nM
|
|
|
|
CP0410307
|
N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]acetamide
Show/Hide
|
C30H27Cl3N4O2
|
1
|
| 1 |
Ki = 214 nM
|
|
|
|
CP0385622
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-4-methylpentanamide
Show/Hide
|
C28H30Cl2N6O
|
1
|
| 1 |
Ki = 215 nM
|
|
|
|
CP0946879
|
3-[5-(2-Cyano-4-fluorophenyl)-1,3,4-oxadiazol-2-yl]-N-[9-(2-fluoroethyl)-9H-carbazol-3-yl]propanamide
Show/Hide
|
C26H19F2N5O2
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0379530
|
N-[9-[9-aminononyl(methyl)amino]nonyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C36H52Cl3N5O
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0410196
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-propylurea
Show/Hide
|
C32H32Cl3N5O2
|
1
|
| 1 |
Ki = 293 nM
|
|
|
|
CP0417230
|
N-[11-(11-aminoundecylamino)undecyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C39H58Cl3N5O
|
1
|
| 1 |
Ki = 305 nM
|
|
|
|
CP0852535
|
3-[5-(4-Bromo-2-fluorophenyl)-1,3,4-oxadiazol-2-yl]-N-[9-(2-fluoroethyl)-9H-carbazol-3-yl]propanamide
Show/Hide
|
C25H19BrF2N4O2
|
1
|
| 1 |
Ki = 318 nM
|
|
|
|
CP0375172
|
6-methoxy-3-[(2-methoxyphenyl)methyl]-5,7,8-trimethylchromen-2-one
Show/Hide
|
C21H22O4
|
1
|
| 1 |
Ki = 338 nM
|
|
|
|
CP0399622
|
1-(2-ethoxyethyl)-8-methoxy-4-oxo-N-(2-phenylethyl)quinoline-3-carboxamide
Show/Hide
|
C23H26N2O4
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0474423
|
N-[9-(9-aminononylamino)nonyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C35H50Cl3N5O
|
1
|
| 1 |
Ki = 419 nM
|
|
|
|
CP0375653
|
N-[11-[11-aminoundecyl(methyl)amino]undecyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C40H60Cl3N5O
|
1
|
| 1 |
Ki = 426 nM
|
|
|
|
CP0391995
|
US9187480, ethyl N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}carbamate
Show/Hide
|
C25H24Cl2N6O2
|
1
|
| 1 |
Ki = 426 nM
|
|
|
|
CP0482465
|
6-(4-benzylpiperazin-1-yl)-8-(2-chlorophenyl)-9-(4-chlorophenyl)purine
Show/Hide
|
C28H24Cl2N6
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0375171
|
3-[(4-fluorophenyl)methyl]-6-hydroxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C19H17FO3
|
1
|
| 1 |
Ki = 444 nM
|
|
|
|
CP0374242
|
5-(4-chlorophenyl)-N-[5-[5-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]pentylamino]pentyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C44H43Cl6N7O2
|
1
|
| 1 |
Ki = 451 nM
|
|
|
|
CP0412596
|
2-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]-2-phenylacetonitrile
Show/Hide
|
C29H23Cl2N7
|
1
|
| 1 |
Ki = 460 nM
|
|
|
|
CP0501831
|
9-Chloro-1-(2,4-dichlorophenyl)-N-piperidin-1-yl-4,5,6,7-tetrahydro-1H-benzo[7,8]cycloocta[1,2-c]pyrazole-3-carboxamide
Show/Hide
|
C25H25Cl3N4O
|
1
|
| 1 |
Ki = 492 nM
|
|
|
|
CP0410104
|
5-(4-chlorophenyl)-N-[3-[3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]propylamino]propyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C40H35Cl6N7O2
|
1
|
| 1 |
Ki = 496 nM
|
|
|
|
CP0375363
|
(6R)-2-ethyl-6,9,9-trimethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C18H24O2
|
1
|
| 1 |
Ki = 510 nM
|
|
|
|
CP0400113
|
5-(4-chlorophenyl)-N-[7-[7-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]heptylamino]heptyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C48H51Cl6N7O2
|
1
|
| 1 |
Ki = 553 nM
|
|
|
|
CP0391994
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-2-cyclopentylacetamide
Show/Hide
|
C29H30Cl2N6O
|
1
|
| 1 |
Ki = 569 nM
|
|
|
|
CP0374915
|
3-[(4-chlorophenyl)methyl]-5-methoxy-7-pentylchromen-2-one
Show/Hide
|
C22H23ClO3
|
1
|
| 1 |
Ki = 578 nM
|
|
|
|
CP0393585
|
3-[(4-bromophenyl)methyl]-5-methoxy-7-pentylchromen-2-one
Show/Hide
|
C22H23BrO3
|
1
|
| 1 |
Ki = 578 nM
|
|
|
|
CP0374241
|
N-[7-(7-aminoheptylamino)heptyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C31H42Cl3N5O
|
1
|
| 1 |
Ki = 622 nM
|
|
|
|
CP0412605
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-pyridin-4-ylethyl)piperazin-1-yl]purine
Show/Hide
|
C28H25Cl2N7
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0393598
|
6-methoxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-one
Show/Hide
|
C21H22O3
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0375364
|
(9R)-3,6,6,9-tetramethyl-7,8,9,10-tetrahydrobenzo[c]chromen-1-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0474427
|
5-(4-chlorophenyl)-N-[7-[7-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]heptyl-methylamino]heptyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C49H53Cl6N7O2
|
1
|
| 1 |
Ki = 683 nM
|
|
|
|
CP0399453
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-phenylpiperidin-4-yl}acetamide
Show/Hide
|
C30H26Cl2N6O
|
1
|
| 1 |
Ki = 726 nM
|
|
|
|
CP0476824
|
N-tert-butyl-1-(3-fluoropropyl)-8-methoxy-4-oxoquinoline-3-carboxamide
Show/Hide
|
C18H23FN2O3
|
1
|
| 1 |
Ki = 750 nM
|
|
|
|
CP0465702
|
5-(4-Chloro-2,6-dimethylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide
Show/Hide
|
C24H25Cl3N4O
|
1
|
| 1 |
Ki = 758 nM
|
|
|
|
CP0449302
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-[7-(methanesulfonamido)heptyl]-4-methylpyrazole-3-carboxamide
Show/Hide
|
C25H29Cl3N4O3S
|
1
|
| 1 |
Ki = 780 nM
|
|
|
|
CP0375166
|
3-[(2-methoxyphenyl)methyl]-5-methyl-8-propan-2-ylchromen-2-one
Show/Hide
|
C21H22O3
|
1
|
| 1 |
Ki = 795 nM
|
|
|
|
CP0851726
|
6-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxy-cyclohexyl]-pyrazine-2-carboxamide
Show/Hide
|
C21H24ClN3O3
|
1
|
| 1 |
Ki = 801 nM
|
|
|
|
CP0526409
|
US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1,4-thiomorpholine-1,1-dione
Show/Hide
|
C21H17Cl2N5O2S
|
1
|
| 1 |
Ki = 834 nM
|
|
|
|
CP0441121
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}cyclohexanecarboxamide
Show/Hide
|
C29H30Cl2N6O
|
1
|
| 1 |
Ki = 835 nM
|
|
|
|
CP0901735
|
6-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-2-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 863 nM
|
|
|
|
CP0857532
|
cis/trans-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-((4-(methylsulfonamidomethyl)cyclohexyl)methyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C26H29Cl3N4O3S
|
1
|
| 1 |
Ki = 900 nM
|
|
|
|
CP0428013
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]methanesulfonamide
Show/Hide
|
C29H26Cl2N6O2S
|
1
|
| 1 |
Ki = 948 nM
|
|
|
|
CP0442559
|
US9187480, N-{4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexyl}methanesulfonamide
Show/Hide
|
C30H27Cl2N5O2S
|
1
|
| 1 |
Ki = 948 nM
|
|
|
|
CP0475994
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]cyclohexanecarboxamide
Show/Hide
|
C26H27Cl2N3O2
|
1
|
| 1 |
Ki = 953 nM
|
|
|
|
CP0396686
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-[[4-(methanesulfonamidomethyl)cyclohexyl]methyl]-4-methylpyrazole-3-carboxamide
Show/Hide
|
C26H29Cl3N4O3S
|
1
|
| 1 |
Ki = 960 nM
|
|
|
|
CP0416807
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(1,5-dimethylpyrazol-4-yl)methyl]piperazin-1-yl]purine
Show/Hide
|
C27H26Cl2N8
|
1
|
| 1 |
Ki = 990 nM
|
|
|
|
CP0400268
|
(6R)-4,6,9,9-tetramethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0440585
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[7-(sulfamoylamino)heptyl]pyrazole-3-carboxamide
Show/Hide
|
C24H28Cl3N5O3S
|
1
|
| 1 |
Ki = 1010 nM
|
|
|
|
CP0379515
|
5-(4-chlorophenyl)-N-[5-[5-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]pentyl-methylamino]pentyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C45H45Cl6N7O2
|
1
|
| 1 |
Ki = 1037 nM
|
|
|
|
CP0418515
|
1,5-bis(2,4-Dichlorophenyl)-4-methyl-N-piperidin-1-yl-1Hpyrazole-3-carboxamide
Show/Hide
|
C22H20Cl4N4O
|
1
|
| 1 |
Ki = 1044 nM
|
|
|
|
CP0385621
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}pentanamide
Show/Hide
|
C27H28Cl2N6O
|
1
|
| 1 |
Ki = 1046 nM
|
|
|
|
CP0413829
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]methanesulfonamide
Show/Hide
|
C23H22Cl2N6O2S
|
1
|
| 1 |
Ki = 1073 nM
|
|
|
|
CP0477939
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(1-pyridin-4-ylethyl)piperazin-1-yl]purine
Show/Hide
|
C28H25Cl2N7
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0373943
|
5-(2,4-Dichlorophenyl)-4-methyl-N-piperidin-1-yl-1-(2,4,6-trichlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C22H19Cl5N4O
|
1
|
| 1 |
Ki = 1109 nM
|
|
|
|
CP0415524
|
5-(4-Chloro-2-methylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H23Cl3N4O
|
1
|
| 1 |
Ki = 1124 nM
|
|
|
|
CP0444204
|
(4-amino-4-phenylpiperidin-1-yl)-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazol-3-yl]methanone
Show/Hide
|
C28H25Cl3N4O
|
1
|
| 1 |
Ki = 1127 nM
|
|
|
|
CP0386827
|
(2E,4E,9E,12E)-N-(2-methylbutyl)hexadeca-2,4,9,12-tetraenamide
Show/Hide
|
C21H35NO
|
1
|
| 1 |
Ki = 1210 nM
|
|
|
|
CP0410303
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[(3R)-1-methylsulfonylpiperidin-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C23H23Cl3N4O3S
|
1
|
| 1 |
Ki = 1248 nM
|
|
|
|
CP0868210
|
6-(Cyclopropylmethoxy)-5-(3,4-dichlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H24Cl2N2O3
|
1
|
| 1 |
Ki = 1260 nM
|
|
|
|
CP0379528
|
5-(4-chlorophenyl)-N-[2-[2-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]ethylamino]ethyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C38H31Cl6N7O2
|
1
|
| 1 |
Ki = 1285 nM
|
|
|
|
CP0412606
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(1-phenylethyl)piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0482464
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-pyridin-2-ylpiperazin-1-yl)purine
Show/Hide
|
C26H21Cl2N7
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0394936
|
3-[(4-fluorophenyl)methyl]-6-methoxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C20H19FO3
|
1
|
| 1 |
Ki = 1480 nM
|
|
|
|
CP0849146
|
4-(4-Chlorophenyl)-5-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-2-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 1526 nM
|
|
|
|
CP0481688
|
1-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]urea
Show/Hide
|
C27H29Cl2N7O
|
1
|
| 1 |
Ki = 1548 nM
|
|
|
|
CP0375125
|
6-hydroxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-one
Show/Hide
|
C20H20O3
|
1
|
| 1 |
Ki = 1560 nM
|
|
|
|
CP0488603
|
1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-amine
Show/Hide
|
C28H24Cl2N6
|
1
|
| 1 |
Ki = 1657 nM
|
|
|
|
CP0500311
|
US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexan-1-amine
Show/Hide
|
C29H25Cl2N5
|
1
|
| 1 |
Ki = 1657 nM
|
|
|
|
CP0392474
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(pyridin-4-ylmethyl)piperazin-1-yl]purine
Show/Hide
|
C27H23Cl2N7
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0540679
|
tert-butyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]carbamate
Show/Hide
|
C27H28Cl2N6O2
|
1
|
| 1 |
Ki = 1713 nM
|
|
|
|
CP0259522
|
5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid pyridin-4-ylamide
Show/Hide
|
C22H15Cl3N4O
|
1
|
| 1 |
Ki = 1740 nM
|
|
|
|
CP0409866
|
3-benzyl-6-methoxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C20H20O3
|
1
|
| 1 |
Ki = 1770 nM
|
|
|
|
CP0419054
|
5-(4-Chloro-2-methylphenyl)-4-methyl-N-piperidin-1-yl-1-(2,4,6-trichlorophenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C23H22Cl4N4O
|
1
|
| 1 |
Ki = 1781 nM
|
|
|
|
CP0477728
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[[4-[(sulfamoylamino)methyl]cyclohexyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H28Cl3N5O3S
|
1
|
| 1 |
Ki = 1790 nM
|
|
|
|
CP0410105
|
N-[7-[7-aminoheptyl(methyl)amino]heptyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C32H44Cl3N5O
|
1
|
| 1 |
Ki = 1934 nM
|
|
|
|
CP0866738
|
5-[2-Chloro-5-(trifluoromethyl)phenyl]-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H24ClF3N2O3
|
1
|
| 1 |
Ki = 2080 nM
|
|
|
|
CP0416809
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-phenylethyl)piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0428940
|
tert-butyl N-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]carbamate
Show/Hide
|
C33H33Cl3N4O3
|
1
|
| 1 |
Ki = 2110 nM
|
|
|
|
CP0410194
|
1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-(ethylamino)piperidine-4-carboxamide
Show/Hide
|
C25H26Cl3N5O2
|
1
|
| 1 |
Ki = 2217 nM
|
|
|
|
CP0441119
|
US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}methanesulfonamide
Show/Hide
|
C26H28Cl2N6O2S
|
1
|
| 1 |
Ki = 2230 nM
|
|
|
|
CP0444475
|
N-(1-acetylpiperidin-4-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C24H23Cl3N4O2
|
1
|
| 1 |
Ki = 2236 nM
|
|
|
|
CP0920612
|
5-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamido)-1,2-dimethylpyridinium iodide
Show/Hide
|
C24H20Cl3IN4O
|
1
|
| 1 |
Ki = 2270 nM
|
|
|
|
CP0540695
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-fluorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl2FN6
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0473553
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[[4-[(sulfamoylamino)methyl]cyclohexyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H28Cl3N5O3S
|
1
|
| 1 |
Ki = 2310 nM
|
|
|
|
CP0399454
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}-2-cyclohexylacetamide
Show/Hide
|
C30H32Cl2N6O
|
1
|
| 1 |
Ki = 2360 nM
|
|
|
|
CP0504314
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-hexylurea
Show/Hide
|
C35H38Cl3N5O2
|
1
|
| 1 |
Ki = 2414 nM
|
|
|
|
CP0441755
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]-3-propan-2-ylurea
Show/Hide
|
C26H27Cl2N7O
|
1
|
| 1 |
Ki = 2453 nM
|
|
|
|
CP0430709
|
ethyl (3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C25H25Cl3N4O3
|
1
|
| 1 |
Ki = 2507 nM
|
|
|
|
CP0474039
|
tert-butyl 4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C27H29Cl3N4O3
|
1
|
| 1 |
Ki = 2510 nM
|
|
|
|
CP0902668
|
5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1S,2S)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki = 2637 nM
|
|
|
|
CP0415521
|
4-[2-(4-aminooxan-4-yl)-1,3-thiazol-4-yl]-2,6-ditert-butylphenol
Show/Hide
|
C22H32N2O2S
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
|
CP0444202
|
1-butyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H34Cl3N5O2
|
1
|
| 1 |
Ki = 2760 nM
|
|
|
|
CP0428944
|
ethyl 4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C25H25Cl3N4O3
|
1
|
| 1 |
Ki = 2997 nM
|
|
|
|
CP0427068
|
(3R)-N-butyl-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
|
C27H30Cl3N5O2
|
1
|
| 1 |
Ki = 3031 nM
|
|
|
|
CP0409459
|
(3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
|
C26H28Cl3N5O2
|
1
|
| 1 |
Ki = 3090 nM
|
|
|
|
CP0432518
|
N-[(8R)-2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
Ki = 3290 nM
|
|
|
|
CP0428943
|
N-tert-butyl-4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
|
C27H30Cl3N5O2
|
1
|
| 1 |
Ki = 3349 nM
|
|
|
|
CP0375117
|
3-benzyl-6-hydroxy-5,7,8-trimethylchromen-2-one
Show/Hide
|
C19H18O3
|
1
|
| 1 |
Ki = 3420 nM
|
|
|
|
CP0475976
|
3-[[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]methyl]-5-methyl-1,2,4-oxadiazole
Show/Hide
|
C25H22Cl2N8O
|
1
|
| 1 |
Ki = 3600 nM
|
|
|
|
CP0440586
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(6-methylpyridin-3-yl)pyrazole-3-carboxamide
Show/Hide
|
C23H17Cl3N4O
|
1
|
| 1 |
Ki = 4010 nM
|
|
|
|
CP0078849
|
(9Z,12Z)-N-benzyloctadeca-9,12-dienamide
Show/Hide
|
C25H39NO
|
1
|
| 1 |
Ki = 4110 nM
|
|
|
|
CP0410306
|
(3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propan-2-ylpiperidine-1-carboxamide
Show/Hide
|
C26H28Cl3N5O2
|
1
|
| 1 |
Ki = 4135 nM
|
|
|
|
CP0379221
|
(6R)-6,9,9-trimethyl-5,6,7,8-tetrahydroxanthen-3-ol
Show/Hide
|
C16H20O2
|
1
|
| 1 |
Ki = 4200 nM
|
|
|
|
CP0410197
|
N-[(3S)-1-acetylpiperidin-3-yl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C24H23Cl3N4O2
|
1
|
| 1 |
Ki = 4350 nM
|
|
|
|
CP0385619
|
US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(trifluoromethanesulfonylmethyl)piperidin-1-yl]-9H-purine
Show/Hide
|
C23H19Cl2F3N6O2S
|
1
|
| 1 |
Ki = 4501 nM
|
|
|
|
CP0500549
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-(1-hydroxypyridin-4-ylidene)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C22H15Cl3N4O2
|
1
|
| 1 |
Ki = 4520 nM
|
|
|
|
CP0412604
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-methylphenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0413825
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-ethylurea
Show/Hide
|
C31H29Cl2N7O
|
1
|
| 1 |
Ki = 4645 nM
|
|
|
|
CP0447777
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-propan-2-ylurea
Show/Hide
|
C32H32Cl3N5O2
|
1
|
| 1 |
Ki = 4914 nM
|
|
|
|
CP0540698
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(2-methoxyphenyl)piperazin-1-yl]purine
Show/Hide
|
C28H24Cl2N6O
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0456341
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(4-fluorophenyl)piperazin-1-yl]purine
Show/Hide
|
C27H21Cl2FN6
|
1
|
| 1 |
Ki = 5100 nM
|
|
|
|
CP0895933
|
(R,S)-N-[2-(2-Chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydro-2H-oxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
Ki = 5400 nM
|
|
|
|
CP0409458
|
ethyl (3S)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C25H25Cl3N4O3
|
1
|
| 1 |
Ki = 5420 nM
|
|
|
|
CP0428016
|
1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C29H25Cl3N4O2
|
1
|
| 1 |
Ki = 5504 nM
|
|
|
|
CP0499944
|
1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C29H24Cl2N6O
|
1
|
| 1 |
Ki = 5507 nM
|
|
|
|
CP0466917
|
US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-1-phenylcyclohexane-1-carboxamide
Show/Hide
|
C30H25Cl2N5O
|
1
|
| 1 |
Ki = 5507 nM
|
|
|
|
CP0428939
|
4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-ethylpiperidine-1-carboxamide
Show/Hide
|
C25H26Cl3N5O2
|
1
|
| 1 |
Ki = 5693 nM
|
|
|
|
CP0428014
|
N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C28H24Cl2N6O2S
|
1
|
| 1 |
Ki = 5865 nM
|
|
|
|
CP0494087
|
2,6-ditert-butyl-4-[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]phenol
Show/Hide
|
C20H30N2OS
|
1
|
| 1 |
Ki = 6237 nM
|
|
|
|
CP0489872
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-ethoxyacetamide
Show/Hide
|
C23H23Cl2N3O3
|
1
|
| 1 |
Ki = 6540 nM
|
|
|
|
CP0423937
|
tert-butyl (3R)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxylate
Show/Hide
|
C27H29Cl3N4O3
|
1
|
| 1 |
Ki = 6720 nM
|
|
|
|
CP0393599
|
3-[(2-methoxyphenyl)methyl]-5,8-dimethylchromen-2-one
Show/Hide
|
C19H18O3
|
1
|
| 1 |
Ki = 6830 nM
|
|
|
|
CP0295447
|
1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide
Show/Hide
|
C25H25Cl2N7O
|
1
|
| 1 |
Ki = 7700 nM
|
|
|
|
CP0428011
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-propylurea
Show/Hide
|
C32H31Cl2N7O
|
1
|
| 1 |
Ki = 7779 nM
|
|
|
|
CP0432562
|
(3S)-3-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
|
C26H28Cl3N5O2
|
1
|
| 1 |
Ki = 7795 nM
|
|
|
|
CP0444203
|
4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propylpiperidine-1-carboxamide
Show/Hide
|
C26H28Cl3N5O2
|
1
|
| 1 |
Ki = 8459 nM
|
|
|
|
CP0453395
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-N,2-dimethylpropanamide
Show/Hide
|
C24H25Cl2N3O2
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0447778
|
N-butyl-4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]piperidine-1-carboxamide
Show/Hide
|
C27H30Cl3N5O2
|
1
|
| 1 |
Ki = 8721 nM
|
|
|
|
CP0487977
|
1-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]-3-propan-2-ylurea
Show/Hide
|
C32H31Cl2N7O
|
1
|
| 1 |
Ki = 8946 nM
|
|
|
|
CP0445160
|
(2E,4E,8E,10Z,14Z)-N-(2-methylpropyl)octadeca-2,4,8,10,14-pentaen-12-ynamide
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 9180 nM
|
|
|
|
CP0474072
|
4-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]-N-propan-2-ylpiperidine-1-carboxamide
Show/Hide
|
C26H28Cl3N5O2
|
1
|
| 1 |
Ki = 9791 nM
|
|
|
|
CP0136518
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-methyl-6-(2,2,2-trifluoroethyl)pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
|
C20H13Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0371731
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-cyclohexyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C23H20Cl2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0371732
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-isopropyl-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C22H17Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0371733
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(3,3,3-trifluoropropyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C20H13Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0371734
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-propyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C20H16Cl2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392052
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2-fluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H13Cl2FN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392053
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(piperidin-1-yl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C22H19Cl2N5O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0401262
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[3,4-c]pyridin-7(6H)-one
Show/Hide
|
C20H12Cl2F3N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0401263
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-5-ethyl-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C21H15Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435517
|
3-(2-chlorophenyl)-2-(4-chlorophenyl)-6-cyclohexyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C23H20Cl2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435518
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-difluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H12Cl2F2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0441836
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[3,4-d]pyridazin-7(6H)-one
Show/Hide
|
C19H11Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0441837
|
6-benzyl-2-(2-chlorophenyl)-3-(4-chlorophenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C24H16Cl2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0442487
|
3-(2-chlorophenyl)-2-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H11Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0442489
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2-difluoropropyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C20H14Cl2F2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0449529
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-ethyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H14Cl2N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0457027
|
2-(2-chlorophenyl)-3-(4-chlorophenyl)-6-(2,2,2-trifluoroethyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
Show/Hide
|
C19H11Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0859347
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-1-(2,2,2-trifluoroethyl)-4,9-dihydro-1H-purin-6(5H)-one
Show/Hide
|
C19H13Cl2F3N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0037081
|
PF-514273
Show/Hide
|
C21H17Cl2F2N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375105
|
7-(1-butylcyclohexyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-one
Show/Hide
|
C28H34O4
|
1
|
| 1 |
Ki >= 10000 nM
|
|
|
|
CP0375124
|
3-Benzyl-5-isopropyl-8-methylchromen-2-one
Show/Hide
|
C20H20O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375165
|
5-methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one
Show/Hide
|
C28H36O4
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0393582
|
3-Benzyl-5-methoxy-7-methylchromen-2-one
Show/Hide
|
C18H16O3
|
1
|
| 1 |
Ki >= 10000 nM
|
|
|
|
CP0393584
|
3-[(2-hydroxyphenyl)methyl]-8-methyl-5-propan-2-ylchromen-2-one
Show/Hide
|
C20H20O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0393614
|
5-Isopropyl-3,8-dimethylchromen-2-one
Show/Hide
|
C14H16O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0057830
|
5-(4-chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-methoxyethoxy)pyridine-3-carboxamide
Show/Hide
|
C21H25ClN2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0849147
|
5-(4-Chloro-phenyl)-6-cyclopropylmethoxy-N-piperidin-1-yl-3-pyridinecarboxamide
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0851725
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(phenoxy)-3-pyridinecarboxamide
Show/Hide
|
C24H23ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0851727
|
5-(4-Cyanophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0866737
|
6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-methoxyphenyl)-3-pyridinecarboxamide
Show/Hide
|
C23H28N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0866739
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-pyrimidinylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C23H23ClN4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0868207
|
6-Butoxy-5-(4-chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0868209
|
6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-sulfamoyl-phenyl)-3-pyridinecarboxamide
Show/Hide
|
C22H27N3O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0874120
|
5-(4-Chlorophenyl)-6-(2-cyclopropylethyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H27ClN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0882319
|
5-(4-Chlorophenyl)-6-(cyclopentyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H27ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0884635
|
6-(Cyclopropylmethoxy)-5-(4-fluorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25FN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0884636
|
5-(4-Chlorophenyl)-6-cyclobutoxy-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0884637
|
4-[2-Cyclopropylmethoxy-5-((1R,2R)-2-hydroxy-cyclohexylcarbamoyl)-pyridin-3-yl]-benzoic Acid
Show/Hide
|
C23H26N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0884639
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-[(3-methyl-5-isoxazolyl)methoxy]-3-pyridinecarboxamide
Show/Hide
|
C23H24ClN3O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893867
|
5-(4-Chlorophenyl)-6-(cyclohexyloxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C24H29ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893869
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(1-methylethoxy)-3-pyridinecarboxamide
Show/Hide
|
C21H25ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893881
|
6-(Cyclopropylmethoxy)-5-(4-trifluoromethylphenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H25F3N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893882
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C24H24ClN3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0893915
|
5-(2-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0898833
|
5-(4-Carbamoyl-phenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0899224
|
5-(4-Chlorophenyl)-6-[(cyclopropylmethyl)methylamino]-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0901736
|
5-(4-Chlorophenyl)-N-[(2R)-2-cyclopropyl-2-hydroxypropyl]-6-(cyclopropylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0901741
|
6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-[4-(trifluoromethoxy)phenyl]-3-pyridinecarboxamide
Show/Hide
|
C23H25F3N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0911979
|
6-(Cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-5-(4-methanesulfonylamino-phenyl)-3-pyridinecarboxamide
Show/Hide
|
C23H29N3O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0943808
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(phenylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C25H25ClN2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0946962
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(4-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C24H24ClN3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0953332
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(3-pyridinylmethoxy)-3-pyridinecarboxamide
Show/Hide
|
C24H24ClN3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375365
|
(6R)-3,6,9,9-tetramethyl-5,6,7,8-tetrahydroxanthen-1-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375366
|
(9R)-4,6,6,9-tetramethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C17H22O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375368
|
(9R)-6,6,9-trimethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C16H20O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0455894
|
(9R)-2-ethyl-6,6,9-trimethyl-7,8,9,10-tetrahydrobenzo[c]chromen-3-ol
Show/Hide
|
C18H24O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0228439
|
1-(4-chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
Show/Hide
|
C22H21ClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392473
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(3-chloropyridin-4-yl)methyl]piperazin-1-yl]purine
Show/Hide
|
C27H22Cl3N7
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0393418
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl3N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0393593
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0412607
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl2FN6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0456334
|
3-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]phenol
Show/Hide
|
C27H22Cl2N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0456342
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]purine
Show/Hide
|
C28H24Cl2N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0477938
|
2-[[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]methyl]benzonitrile
Show/Hide
|
C29H23Cl2N7
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489825
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl3N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0539037
|
4-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]benzonitrile
Show/Hide
|
C28H21Cl2N7
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0539038
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[[2-(trifluoromethoxy)phenyl]methyl]piperazin-1-yl]purine
Show/Hide
|
C29H23Cl2F3N6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0539040
|
2-[4-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperazin-1-yl]benzonitrile
Show/Hide
|
C28H21Cl2N7
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0540696
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-phenylpiperazin-1-yl)purine
Show/Hide
|
C27H22Cl2N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0540697
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(4-methylphenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C29H26Cl2N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0542767
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]purine
Show/Hide
|
C29H23Cl2F3N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0542768
|
8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-[4-[(3-chlorophenyl)methyl]piperazin-1-yl]purine
Show/Hide
|
C28H23Cl3N6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0385623
|
phenyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]piperidin-4-yl]carbamate
Show/Hide
|
C29H24Cl2N6O2
|
1
|
| 1 |
Ki = 10649 nM
|
|
|
|
CP0418248
|
US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]piperidin-4-yl}benzamide
Show/Hide
|
C29H24Cl2N6O
|
1
|
| 1 |
Ki = 10649 nM
|
|
|
|
CP0441118
|
US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}methyl)cyclohexyl]methyl}aminosulfonamide
Show/Hide
|
C25H27Cl2N7O2S
|
1
|
| 1 |
Ki = 10719 nM
|
|
|
|
CP0385359
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-[(3S)-1-methylsulfonylpiperidin-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C23H23Cl3N4O3S
|
1
|
| 1 |
Ki = 10893 nM
|
|
|
|
CP0517368
|
N-[(8S)-2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylpropanamide
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0467377
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2-oxazole-5-carboxamide
Show/Hide
|
C23H18Cl2N4O3
|
1
|
| 1 |
Ki = 12100 nM
|
|
|
|
CP0428015
|
tert-butyl 4-[[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]amino]piperidine-1-carboxylate
Show/Hide
|
C27H28Cl2N6O2
|
2
|
| 1 |
Ki = 13599 nM
|
|
|
| 2 |
Ki = 14000 nM
|
|
|
|
CP0488601
|
tert-butyl N-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]carbamate
Show/Hide
|
C33H32Cl2N6O2
|
1
|
| 1 |
Ki = 13947 nM
|
|
|
|
CP0441039
|
1-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-3-ethylurea
Show/Hide
|
C22H22Cl2N4O2
|
1
|
| 1 |
Ki = 14700 nM
|
|
|
|
CP0434132
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]oxane-4-carboxamide
Show/Hide
|
C25H25Cl2N3O3
|
1
|
| 1 |
Ki = 15200 nM
|
|
|
|
CP0459284
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methoxyacetamide
Show/Hide
|
C22H21Cl2N3O3
|
1
|
| 1 |
Ki = 15400 nM
|
|
|
|
CP0410301
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-[4-(dimethylamino)phenyl]urea
Show/Hide
|
C37H35Cl3N6O2
|
1
|
| 1 |
Ki = 16289 nM
|
|
|
|
CP0462175
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]propanamide
Show/Hide
|
C22H21Cl2N3O2
|
1
|
| 1 |
Ki = 16600 nM
|
|
|
|
CP0420951
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C23H18Cl2N4O3
|
1
|
| 1 |
Ki = 16900 nM
|
|
|
|
CP0427061
|
1-benzyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C36H32Cl3N5O2
|
1
|
| 1 |
Ki = 17126 nM
|
|
|
|
CP0428942
|
1-tert-butyl-3-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H34Cl3N5O2
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0434935
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-(4-fluorophenyl)urea
Show/Hide
|
C35H29Cl3FN5O2
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0437612
|
1-[1-[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]-4-phenylpiperidin-4-yl]-3-cyclohexylurea
Show/Hide
|
C35H36Cl3N5O2
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0428012
|
1-tert-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H33Cl2N7O
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0441756
|
N-butyl-4-[[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]amino]piperidine-1-carboxamide
Show/Hide
|
C27H29Cl2N7O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0487976
|
1-butyl-3-[1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-phenylpiperidin-4-yl]urea
Show/Hide
|
C33H33Cl2N7O
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0413149
|
US9187480, N-tert-butyl-1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C33H32Cl2N6O
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0439886
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]acetamide
Show/Hide
|
C21H19Cl2N3O2
|
1
|
| 1 |
Ki = 20600 nM
|
|
|
|
CP0509763
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1-cyanocyclopropane-1-carboxamide
Show/Hide
|
C24H20Cl2N4O2
|
1
|
| 1 |
Ki = 21200 nM
|
|
|
|
CP0424530
|
(2E,4E,9Z)-N-(2-methylpropyl)hexadeca-2,4,9-trien-12,14-diynamide
Show/Hide
|
C20H27NO
|
1
|
| 1 |
Ki = 22550 nM
|
|
|
|
CP0375654
|
N-[5-[5-aminopentyl(methyl)amino]pentyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C28H36Cl3N5O
|
1
|
| 1 |
Ki > 25000 nM
|
|
|
|
CP0375900
|
5-(4-chlorophenyl)-N-[11-[11-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]undecyl-methylamino]undecyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C57H69Cl6N7O2
|
1
|
| 1 |
Ki > 25000 nM
|
|
|
|
CP0406055
|
5-(4-chlorophenyl)-N-[9-[9-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]nonyl-methylamino]nonyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C53H61Cl6N7O2
|
1
|
| 1 |
Ki > 25000 nM
|
|
|
|
CP0409089
|
methyl N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]carbamate
Show/Hide
|
C21H19Cl2N3O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0443609
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-1,2,5-oxadiazole-3-carboxamide
Show/Hide
|
C22H17Cl2N5O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0261493
|
(9Z,12Z,15Z)-N-benzyloctadeca-9,12,15-trienamide
Show/Hide
|
C25H37NO
|
1
|
| 1 |
Ki = 43960 nM
|
|
|
|
CP0404194
|
1-(4-chlorophenyl)-3-[3-(3-pyrrolidin-1-ylphenyl)phenyl]urea
Show/Hide
|
C23H22ClN3O
|
1
|
| 1 |
Ki = 49800 nM
|
|
|
|
CP0233117
|
(9Z,12Z,15Z)-N-[(3-methoxyphenyl)methyl]octadeca-9,12,15-trienamide
Show/Hide
|
C26H39NO2
|
1
|
| 1 |
Ki > 50000 nM
|
|
|
|
CP0404193
|
1-(4-chlorophenyl)-3-[3-[(6-pyrrolidin-1-ylpyridin-2-yl)amino]phenyl]urea
Show/Hide
|
C22H22ClN5O
|
1
|
| 1 |
Ki = 52600 nM
|
|
|
|
CP0409567
|
N-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]-2-methylsulfonylacetamide
Show/Hide
|
C22H21Cl2N3O4S
|
1
|
| 1 |
Ki = 59000 nM
|
|
|
|
CP0443610
|
1-[2-(2-chlorophenyl)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrooxepino[3,2-c]pyrazol-8-yl]pyrrolidin-2-one
Show/Hide
|
C23H21Cl2N3O2
|
1
|
| 1 |
Ki = 75600 nM
|
|
|
|
CP0511698
|
2-(4-chlorophenyl)-N-[3-(3-pyrrolidin-1-ylphenyl)phenyl]acetamide
Show/Hide
|
C24H23ClN2O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0511699
|
1-(4-chlorophenyl)-3-[3-(3-pyrrolidin-1-ylanilino)phenyl]urea
Show/Hide
|
C23H23ClN4O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0051977
|
decyl 4-hydroxy-5-(4-hydroxyphenyl)-2-oxo-1H-pyridine-3-carboxylate
Show/Hide
|
C22H29NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0235951
|
4-hydroxy-5-(4-hydroxyphenyl)-3-octadecanoyl-1H-pyridin-2-one
Show/Hide
|
C29H43NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0306281
|
FARINOSONE A
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0368793
|
3-dodecanoyl-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one
Show/Hide
|
C23H31NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0378922
|
4-hydroxy-5-(4-hydroxyphenyl)-3-octanoyl-1H-pyridin-2-one
Show/Hide
|
C19H23NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374243
|
N-[5-(5-aminopentylamino)pentyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C27H34Cl3N5O
|
1
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| 1 |
Ki > 2500 nM
|
|
|
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CP0374244
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5-(4-chlorophenyl)-N-[11-[11-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]undecylamino]undecyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
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|
C56H67Cl6N7O2
|
1
|
| 1 |
Ki > 2500 nM
|
|
|
|
CP0379529
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N-[2-(2-aminoethylamino)ethyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
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|
C21H22Cl3N5O
|
1
|
| 1 |
Ki > 2500 nM
|
|
|
|
CP0386430
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5-(4-chlorophenyl)-N-[9-[9-[[5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carbonyl]amino]nonylamino]nonyl]-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C52H59Cl6N7O2
|
1
|
| 1 |
Ki > 2500 nM
|
|
|
|
CP0410102
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N-[3-(3-aminopropylamino)propyl]-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
Show/Hide
|
C23H26Cl3N5O
|
1
|
| 1 |
Ki > 2500 nM
|
|
|
|
CP0895354
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5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-pyridazine-3-carboxamide
Show/Hide
|
C21H24ClN3O3
|
1
|
| 1 |
Ki > 3000 nM
|
|
|
|
CP0884638
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6-(Cyclopropylmethoxy)-5-(2,4-dichlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
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|
C22H24Cl2N2O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0893868
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5-(3-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0953345
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5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2S)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0849154
|
5-(4-Chlorophenyl)-N-[(1R,2R)-2-hydroxycyclohexyl]-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
Show/Hide
|
C20H20ClF3N2O3
|
1
|
| 1 |
Ki > 7000 nM
|
|
|
|
CP0851724
|
5-(4-Chlorophenyl)-6-(cyclopropylmethoxy)-N-[(1R,2R)-2-hydroxycyclohexyl]-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 7000 nM
|
|
|
|
CP0868208
|
5-(4-Chloro-phenyl)-6-cyclopropylmethoxy-N-((1S,2R)-2-hydroxy-cyclohexyl)-3-pyridinecarboxamide
Show/Hide
|
C22H25ClN2O3
|
1
|
| 1 |
Ki > 7000 nM
|
|
|
