General Information of the Compound
Compound ID
CP0363620
Compound Name
2-[(4-ethoxyphenyl)methyl]-1-(3-methylbutyl)-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]benzimidazole-5-carboxamide
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Structure
Formula
C39H47N5O2
Molecular Weight
617.838
Canonical SMILES
CCOc1ccc(Cc2nc3cc(ccc3n2CCC(C)C)C(=O)NCCCCNc2c3CCCCc3nc3ccccc23)cc1
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InChI
InChI=1S/C39H47N5O2/c1-4-46-30-18-15-28(16-19-30)25-37-43-35-26-29(17-20-36(35)44(37)24-21-27(2)3)39(45)41-23-10-9-22-40-38-31-11-5-7-13-33(31)42-34-14-8-6-12-32(34)38/h5,7,11,13,15-20,26-27H,4,6,8-10,12,14,21-25H2,1-3H3,(H,40,42)(H,41,45)
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InChIKey
YWNNZVOAUVSVFF-UHFFFAOYSA-N
Physicochemical Property
logP
8.121
Rotatable Bonds
14
Heavy Atom Count
46
Polar Areas
81.07
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155530802
ChEMBL ID
CHEMBL4464883
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 911 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2400 nM
   TI
   LI
   LO
   TS