Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpiperidin-2-yl)methyl]-1H-indole
    Show/Hide
 PubChem ID
CID: 10141893
SID: 15133103
Canonical SMILES
CN1CCCCC1Cn1cc(C(=O)c2cc(ccc2I)[N+]([O-])=O)c2ccccc12
    Show/Hide
Compound Formula C22H22IN3O3
Compound Structure
Protein Name
 Protein Info 
Cannabinoid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Cannabinoid receptor
Uniprot ID
P34972
Gene Name
CNR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 16.4 nM
   TI
   LI
   LO
   TS
2
Ki = 21.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.4 nM
2 Ki = 3.4 nM
3 Ki = 11.5 nM
4 Ki = 15.1 nM