Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT07030 , Dedicator of cytokinesis protein 5
 Protein Info 
Gene Name DOCK5
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID Q9H7D0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT07030
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0562783
 Compound Info 
7-[(3-chlorophenyl)methyl]-2-(4-methoxy-3-methylphenyl)-2,7-diazaspiro[4.4]nonan-1-one
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C22H25ClN2O2
  1
1
IC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451670
 Compound Info 
7-[(3-chlorophenyl)methyl]-2-(3-fluorophenyl)-2,7-diazaspiro[4.4]nonan-1-one
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C20H20ClFN2O
  1
1
IC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552299
 Compound Info 
(4S,5R)-1,1-dioxo-2-phenyl-7-(quinolin-3-ylmethyl)-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C22H23N3O3S
  1
1
IC50 = 22000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552171
 Compound Info 
(4S,5R)-7-[(3-chlorophenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C19H21ClN2O3S
  1
1
IC50 = 24000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575602
 Compound Info 
(4S,5R)-7-[(3,4-dichlorophenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C19H20Cl2N2O3S
  1
1
IC50 = 29000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572930
 Compound Info 
(4S,5R)-7-(2,3-dihydro-1H-inden-5-ylmethyl)-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C22H26N2O3S
  1
1
IC50 = 32000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548573
 Compound Info 
(4S,5R)-7-[(1-methylindol-3-yl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C22H25N3O3S
  1
1
IC50 = 33000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572110
 Compound Info 
(4S,5R)-7-[(2-chlorophenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C19H21ClN2O3S
  1
1
IC50 = 35000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572931
 Compound Info 
(4S,5R)-7-[(4-chlorophenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
   Show/Hide
C19H21ClN2O3S
  1
1
IC50 = 36000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537590
 Compound Info 
(4S,5R)-7-[(3-fluoro-4-methoxyphenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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C20H23FN2O4S
  1
1
IC50 = 44000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS