General Information of the Compound
Compound ID
CP0575602
Compound Name
(4S,5R)-7-[(3,4-dichlorophenyl)methyl]-1,1-dioxo-2-phenyl-1lambda6-thia-2,7-diazaspiro[4.4]nonan-4-ol
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Structure
Formula
C19H20Cl2N2O3S
Molecular Weight
427.353
Canonical SMILES
O[C@H]1CN(c2ccccc2)S(=O)(=O)[C@@]11CCN(Cc2ccc(Cl)c(Cl)c2)C1
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InChI
InChI=1S/C19H20Cl2N2O3S/c20-16-7-6-14(10-17(16)21)11-22-9-8-19(13-22)18(24)12-23(27(19,25)26)15-4-2-1-3-5-15/h1-7,10,18,24H,8-9,11-13H2/t18-,19+/m0/s1
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InChIKey
JNVNZYPKNHVNMU-RBUKOAKNSA-N
Physicochemical Property
logP
3.1488
Rotatable Bonds
3
Heavy Atom Count
27
Polar Areas
60.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 139577594
ChEMBL ID
CHEMBL4752328
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT07030, Dedicator of cytokinesis protein 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 29000 nM
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