Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT02328 , Mitogen-activated protein kinase kinase kinase kinase 3
 Protein Info 
Gene Name MAP4K3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q8IVH8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT02328
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0257048
 Compound Info 
5-[2-(1-ethylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-(pyridin-4-ylmethoxy)pyridin-2-amine
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C21H25N5OS
  1
1
IC50 = 78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0362701
 Compound Info 
3-(cyclohexylmethoxy)-5-(2-piperidin-4-yl-1,3-thiazol-5-yl)pyridin-2-amine
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C20H28N4OS
  1
1
IC50 = 258 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0019771
 Compound Info 
5-(2-piperidin-4-yl-1,3-thiazol-5-yl)-3-(pyridin-4-ylmethoxy)pyridin-2-amine
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C19H21N5OS
  1
1
IC50 = 278 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533066
 Compound Info 
2-(3-fluorophenyl)-5-(1-piperidin-4-ylpyrazol-4-yl)-1,7-naphthyridin-8-amine
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C22H21FN6
  1
1
IC50 = 490 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0023821
 Compound Info 
3-cyclohexyloxy-5-(2-piperidin-4-yl-1,3-thiazol-5-yl)pyridin-2-amine
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C19H26N4OS
  1
1
IC50 = 645 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0354029
 Compound Info 
3-[1-(2,6-dichloro-3-fluorophenyl)propoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
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C22H24Cl2FN5O
  1
1
IC50 = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0354034
 Compound Info 
2-(2,6-dichloro-3-fluorophenyl)-4-(1-piperidin-4-ylpyrazol-4-yl)furo[2,3-c]pyridin-7-amine
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C21H18Cl2FN5O
  1
1
IC50 = 1220 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489013
 Compound Info 
2-(3-fluorophenyl)-4-(1-piperidin-4-ylpyrazol-4-yl)furo[2,3-c]pyridin-7-amine
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C21H20FN5O
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0031719
 Compound Info 
(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
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C21H22Cl2FN5O
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS