Brief Information of the Compound and Protein
Compound Name
3-(cyclohexylmethoxy)-5-(2-piperidin-4-yl-1,3-thiazol-5-yl)pyridin-2-amine
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Canonical SMILES
Nc1ncc(cc1OCC1CCCCC1)-c1cnc(s1)C1CCNCC1
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Compound Formula C20H28N4OS
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase KHS subfamily
Uniprot ID
Q8IVH8
Gene Name
MAP4K3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 258 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 77 nM