Brief Information of the Cell Line and Protein
Cell Line ID: CL000023 , BTI-Tn-5B1-4
 Cell Line Info 
Synonyms
BTI-TN-5B1-4
BTI-TN5B1-4
BTI-Tn5B14
BTI-Tn 5B1-4
Tn-5B1-4
Tn 5B1-4
Tn5 B1-4
Tn5B1-4
TN5B14
TnH5
High Five
High 5
High-5
High5
Hi-five
Hi-5
Hi5
Tn-5
Category Spontaneously immortalized cell line
Organism
Trichoplusia ni (Cabbage looper)
Cellosaurus ID
CVCL_C190
Protein ID: PT01223 , Aurora kinase B
 Protein Info 
Gene Name AURKB
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q96GD4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000023
 Cell Line Info 
 Protein ID: PT01223
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0477498
 Compound Info 
N-[3-[(E)-2-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]ethenyl]-1H-indazol-5-yl]-2-thiophen-2-ylacetamide
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C27H29N5OS
  1
1
IC50 = 26 nM
 Bioactivity Info 
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CP0376394
 Compound Info 
1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfonamide
   Show/Hide
C22H19N3O2S
  1
1
IC50 = 31 nM
 Bioactivity Info 
   TI
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CP0430624
 Compound Info 
3-methyl-5-(4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styryl)-1H-indazol-5-yl)aniline
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C29H33N5
  1
1
IC50 = 31 nM
 Bioactivity Info 
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CP0430625
 Compound Info 
4-methyl-N-(3-(2-(6-methyl-5-(2-(thiophen-2-yl)acetamido)-1H-indazol-3-yl)vinyl)phenyl)piperazine-1-carboxamide
   Show/Hide
C28H30N6O2S
  1
1
IC50 = 46 nM
 Bioactivity Info 
   TI
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CP0470476
 Compound Info 
5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole
   Show/Hide
C24H22N4
  1
1
IC50 = 46 nM
 Bioactivity Info 
   TI
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CP0470449
 Compound Info 
N-[6-methyl-3-[(E)-2-phenylethenyl]-1H-indazol-5-yl]-2-thiophen-2-ylacetamide
   Show/Hide
C22H19N3OS
  1
1
IC50 = 47 nM
 Bioactivity Info 
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CP0417624
 Compound Info 
4-methyl-3-(3-((4-methylpiperazin-1-yl)methyl)styryl)-1H-indazole-5-carbonitrile
   Show/Hide
C23H25N5
  1
1
IC50 = 59 nM
 Bioactivity Info 
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CP0430626
 Compound Info 
4-methyl-N-(3-(2-(5-(methylsulfonamido)-6-(pyrrolidin-1-yl)-1H-indazol-3-yl)vinyl)phenyl)piperazine-1-carboxamide
   Show/Hide
C26H33N7O3S
  1
1
IC50 = 62 nM
 Bioactivity Info 
   TI
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CP0477501
 Compound Info 
6-(pyrrolidin-1-yl)-3-styryl-1H-indazol-5-amine
   Show/Hide
C19H20N4
  1
1
IC50 = 81 nM
 Bioactivity Info 
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CP0470045
 Compound Info 
N-[4-methyl-3-[(E)-2-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]ethenyl]-1H-indazol-5-yl]-2-thiophen-2-ylacetamide
   Show/Hide
C28H31N5OS
  1
1
IC50 = 99 nM
 Bioactivity Info 
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CP0376393
 Compound Info 
5-nitro-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole
   Show/Hide
C19H18N4O2
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
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CP0477500
 Compound Info 
N-[3-[(E)-2-phenylethenyl]-6-pyrrolidin-1-yl-1H-indazol-5-yl]-2-thiophen-2-ylacetamide
   Show/Hide
C25H24N4OS
  1
1
IC50 = 110 nM
 Bioactivity Info 
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CP0502849
 Compound Info 
N-[6-methyl-3-(2-phenylethynyl)-2H-indazol-5-yl]-2-thiophen-2-ylacetamide
   Show/Hide
C22H17N3OS
  1
1
IC50 = 110 nM
 Bioactivity Info 
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CP0376392
 Compound Info 
N-[6-methyl-3-[(E)-2-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]ethenyl]-1H-indazol-5-yl]-2-thiophen-2-ylacetamide
   Show/Hide
C28H31N5OS
  1
1
IC50 = 130 nM
 Bioactivity Info 
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CP0494484
 Compound Info 
3-[(E)-2-phenylethenyl]-N-(pyridin-2-ylmethyl)-6-pyrrolidin-1-yl-1H-indazol-5-amine
   Show/Hide
C25H25N5
  1
1
IC50 = 130 nM
 Bioactivity Info 
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CP0452085
 Compound Info 
2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-indazol-5-yl)acetamide
   Show/Hide
C26H25N3O3
  1
1
IC50 = 180 nM
 Bioactivity Info 
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CP0504238
 Compound Info 
6-(4-methylpiperazin-1-yl)-N-(pyridin-2-ylmethyl)-3-styryl-1H-indazol-5-amine
   Show/Hide
C26H28N6
  1
1
IC50 = 810 nM
 Bioactivity Info 
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CP0470451
 Compound Info 
2-phenyl-N-(3-(2-phenylcyclopropyl)-1H-indazol-5-yl)acetamide
   Show/Hide
C24H21N3O
  1
1
IC50 = 1640 nM
 Bioactivity Info 
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