General Information of the Compound
| Compound ID |
CP0376394
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| Compound Name |
1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfonamide
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| Structure |
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| Formula |
C22H19N3O2S
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| Molecular Weight |
389.48
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| Canonical SMILES |
O=S(=O)(Cc1ccccc1)Nc1ccc2[nH]nc(\C=C\c3ccccc3)c2c1
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| InChI |
InChI=1S/C22H19N3O2S/c26-28(27,16-18-9-5-2-6-10-18)25-19-12-14-22-20(15-19)21(23-24-22)13-11-17-7-3-1-4-8-17/h1-15,25H,16H2,(H,23,24)/b13-11+
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| InChIKey |
GCKBOFRETXSMFP-ACCUITESSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00980, Aurora kinase A
Protein ID: PT01223, Aurora kinase B