General Information of the Compound
| Compound ID |
CP0470476
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| Compound Name |
5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole
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| Structure |
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| Formula |
C24H22N4
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| Molecular Weight |
366.468
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| Canonical SMILES |
C1CCN(C1)c1cc2[nH]nc(\C=C\c3ccccc3)c2cc1-c1ccncc1
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| InChI |
InChI=1S/C24H22N4/c1-2-6-18(7-3-1)8-9-22-21-16-20(19-10-12-25-13-11-19)24(17-23(21)27-26-22)28-14-4-5-15-28/h1-3,6-13,16-17H,4-5,14-15H2,(H,26,27)/b9-8+
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| InChIKey |
FHSKCOBLBQSSQE-CMDGGOBGSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00980, Aurora kinase A
Protein ID: PT01223, Aurora kinase B