| Compound ID |
Compound Name |
Compound Formula |
|
CP0483183
|
ethyl 5-[(7-oxo-2,3-diphenyl-6-quinolin-6-yl-4H-pyrazolo[1,5-a]pyrimidin-5-yl)amino]-1,3,4-oxadiazole-2-carboxylate
Show/Hide
|
C32H23N7O4
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0570660
|
3-(cyclohexen-1-yl)-2-phenyl-5-(1H-pyrazol-5-ylamino)-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C30H25N7O
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0495782
|
3-(cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(1H-pyrazol-5-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H26N6O2
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0423501
|
2,3-diphenyl-5-(1H-pyrazol-3-ylamino)-6-quinolin-6-yl-4H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C30H21N7O
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0558821
|
6-(4-hydroxyphenyl)-2,3-diphenyl-5-(1H-pyrazol-5-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C27H20N6O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0563606
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyridin-2-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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|
C30H23N5O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0423488
|
6-(1,3-benzodioxol-5-yl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0540694
|
3-(cyclohexen-1-yl)-6-(4-methoxyphenyl)-5-(1,2-oxazol-3-ylamino)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H25N5O3
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0423502
|
ethyl 3-[[6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4H-pyrazolo[1,5-a]pyrimidin-5-yl]amino]pyrazole-1-carboxylate
Show/Hide
|
C31H26N6O4
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0483184
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(1H-pyrazol-5-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H22N6O2
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0130732
|
3-(cyclohexen-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C30H27N5O2
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0568859
|
8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-(2,2,2-trifluoroethylamino)pyrido[4,3-d]pyrimidin-7-one
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|
C22H16BrF3N4O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0423498
|
3-(cyclohexen-1-yl)-5-methyl-2-phenyl-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H24N4O
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0420291
|
CHEMBL4529030
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|
C29H26N6O2
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0444361
|
6-(4-hydroxyphenyl)-5-methyl-2,3-diphenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C25H19N3O2
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0568180
|
8-(4-bromophenyl)-2-(ethylamino)-6-(4-methoxyphenyl)pyrido[4,3-d]pyrimidin-7-one
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|
C22H19BrN4O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0423489
|
6-(3H-benzimidazol-5-yl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C25H24N6O
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0579564
|
8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-(propylamino)pyrido[4,3-d]pyrimidin-7-one
Show/Hide
|
C23H21BrN4O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0444360
|
5-methyl-2-phenyl-3-piperidin-1-yl-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C27H25N5O
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0574624
|
8-(4-bromophenyl)-2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)pyrido[4,3-d]pyrimidin-7-one
Show/Hide
|
C24H21BrN4O2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0482912
|
6-(4-hydroxyphenyl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C24H24N4O2
|
2
|
| 1 |
IC50 = 57 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0451541
|
3-cyclohexyl-5-methyl-2-phenyl-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H26N4O
|
2
|
| 1 |
IC50 = 66 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0444358
|
6-(2-amino-3H-benzimidazol-5-yl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C25H25N7O
|
2
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0558737
|
5-methyl-2,3-diphenyl-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C28H20N4O
|
2
|
| 1 |
IC50 = 97 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0420295
|
5-methyl-2-phenyl-3-piperidin-1-yl-6-pyridin-4-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C23H23N5O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
|
CP0423490
|
4,5-dimethyl-2,3-diphenyl-6-quinolin-6-ylpyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C29H22N4O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0423497
|
5-methyl-2,6-diphenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C24H24N4O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 1340 nM
|
|
|
|
CP0451540
|
3-(cyclopenten-1-yl)-5-methyl-2-phenyl-6-quinolin-6-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C27H22N4O
|
2
|
| 1 |
IC50 < 100 nM
|
|
|
| 2 |
IC50 = 159 nM
|
|
|
|
CP0468880
|
5-methyl-2-phenyl-3-piperidin-1-yl-6-(1H-pyrazol-4-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C21H22N6O
|
2
|
| 1 |
IC50 < 100 nM
|
|
|
| 2 |
IC50 = 1310 nM
|
|
|
|
CP0868989
|
5-((6-aminopyrimidin-4-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868991
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyrimidin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868993
|
5-(isoxazol-4-ylamino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868994
|
5-((5-aminopyrazin-2-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H27N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868995
|
5-((4-amino-1,3,5-triazin-2-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H26N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868996
|
3-(cyclohex-1-en-1-yl)-5-(isoxazol-3-ylamino)-2-phenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868997
|
6-(3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2,3-diphenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H24N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868998
|
6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2,3-diphenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C32H26N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0868999
|
2-(2-fluorophenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H19FN4O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869000
|
5-(aminomethyl)-6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H22N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869002
|
3-(cyclohex-1-en-1-yl)-5-(hydroxymethyl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H25N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869006
|
6-(3-methoxyquinoxalin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]-pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869007
|
6-(4-hydroxyphenyl)-4,5-dimethyl-2-phenyl-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H19N3O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869008
|
6-(6-hydroxypyridin-3-yl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0869009
|
5-(hydroxymethyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H20N4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0883810
|
5-((5-chloropyrimidin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H21ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0883812
|
(S)-(3-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)amino)-1H-pyrazol-1-yl)methyl-2-amino-3-methylbutanoate
Show/Hide
|
C34H33N7O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0883813
|
6-cyclopentyl-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C23H28N4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0884291
|
3-(3,3-difluoropyrrolidin-1-yl)-6-(imidazo[1,2-a]pyridin-6-yl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H20F2N6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0884347
|
5-(aminomethyl)-3-(cyclohex-1-en-1-yl)-6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H26N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0887716
|
6-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-ylamino)pyrazine-2-carbonitrile
Show/Hide
|
C30H21N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0887719
|
6-(4-methoxyphenyl)-3-phenyl-2-(pyridin-2-yl)-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0887720
|
6-(4-ethoxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H23N3O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0887896
|
6-(4-methoxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0887897
|
6-(3,4-dihydroxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H19N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0891282
|
6-(6-methoxypyridin-3-yl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0901579
|
5-((5-hydroxy-1,3,4-thiadiazol-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H20N6O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0901580
|
3-cyclohexenyl-6-(4-methoxyphenyl)-5-(2-methoxypyrimidin-4-ylamino)-2-phenylpyrazolo [1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H28N6O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0901581
|
3-cyclohexenyl-2-phenyl-5-(pyrazin-2-ylamino)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H25N7O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0901582
|
6-(3-(2-(dimethylamino)ethoxy)-4-hydroxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H28N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902485
|
5-((4-hydroxy-1,3,5-triazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902486
|
5-((1,2,4-triazin-3-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H25N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902487
|
N-(7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)acetamide
Show/Hide
|
C29H21N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902488
|
5-((5-amino-1H-pyrazol-3-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902489
|
N-ethyl-5-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)amino)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
|
C32H24N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902490
|
3-(4,4-difluoropiperidin-1-yl)-5-methyl-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H23F2N5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902491
|
6-(2-(aminomethyl)benzo[d]thiazol-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H21N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902492
|
2-amino-N-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)acetamide
Show/Hide
|
C27H23N5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0902493
|
6-(4-aminophenyl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0902494
|
5-methyl-6-(4-oxocyclohex-1-en-1-yl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H21N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904655
|
3-(4,4-difluoropiperidin-1-yl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H24F2N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904656
|
5-methyl-3-phenyl-2-(1H-pyrrol-3-yl)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H19N5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904657
|
5-ethyl-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H23N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904659
|
6-(cinnolin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H19N5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904660
|
(S)-2-amino-N-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)-3-methylbutanamide
Show/Hide
|
C31H31N5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909280
|
5-([1,2,4]triazolo[1,5-c]pyrimidin-7-ylamino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909281
|
5-((5-methyl-1H-pyrazol-3-yl)amino)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H23N7O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909282
|
3-cyclohexenyl-6-(4-hydroxyphenyl)-2-phenyl-5-(pyrazin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H24N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909283
|
6-(5-methyl-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H20N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909735
|
5-amino-6-(4-hydroxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H18N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909737
|
5-hydroxy-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H19N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909738
|
3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-4-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H27N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0909739
|
6-(3-aminophenyl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909740
|
6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxamide
Show/Hide
|
C26H20N4O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909741
|
5-((1H-1,2,4-triazol-5-yl)methyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H21N7O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909742
|
N-methyl-7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxamide
Show/Hide
|
C29H21N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909743
|
N,N-dimethyl-2-(4-(5-methyl-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)phenoxy)acetamide
Show/Hide
|
C29H26N4O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0909744
|
6-(4-hydroxycyclohex-1-enyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H23N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0910019
|
5-((6-aminopyridazin-3-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910020
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(thiazol-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910021
|
5-((1,2,4-thiadiazol-5-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H20N6O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910022
|
5-((1,3,4-thiadiazol-2-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H24N6O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910024
|
5-((5-methoxy-1H-pyrazol-3-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H24N6O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910025
|
5-(aminomethyl)-6-(4-hydroxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H20N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910026
|
methyl 2-(6-(5-methyl-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)benzo[d]thiazol-2-yl)acetate
Show/Hide
|
C29H22N4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910027
|
2-(4-aminophenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910028
|
6-(3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H22N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910029
|
6-(4-methoxyphenyl)-4,5-dimethyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H28N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0910030
|
6-(4-hydroxypiperidin-1-yl)-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0913643
|
3-cyclohexenyl-5-(hydroxymethyl)-6-(4-methoxyphenyl)-4-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H27N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913644
|
(S)-4-(3-cyclohexenyl-5-methyl-7-oxo-2-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)phenyl 2-amino-3-methylbutanoate
Show/Hide
|
C30H32N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915909
|
5-((5-chloropyridin-2-yl)amino)-6(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915910
|
5-(5-hydroxypyridin-2-ylamino)-6(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H23N5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915911
|
6-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)amino)picolinamide
Show/Hide
|
C31H24N6O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915912
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyrimidin-4-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915913
|
6-(4-methoxyphenyl)-5-((2-methoxypyrimidin-4-yl)amino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H24N6O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915914
|
5-((3-methoxy-1,2,4-thiadiazol-5-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H22N6O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915915
|
ethyl 5-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)amino)thiazole-4-carboxylate
Show/Hide
|
C31H25N5O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915916
|
2,3-diphenyl-5-(pyrimidin-4-ylamino)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H21N7O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915917
|
6-(3-chloro-4-hydroxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H18ClN3O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915918
|
5-hydroxy-6-(4-hydroxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H17N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0915919
|
3-cyclohexenyl-5-hydroxy-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H23N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0941829
|
5-((4-amino-1,2,5-oxadiazol-3-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H21N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0941830
|
5-((1,3,5-triazin-2-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H25N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0941831
|
3-(2-fluorophenyl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22FN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0941833
|
6-(4-hydroxy-3-(2-hydroxyethoxy)phenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H23N3O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942331
|
6-(4-methoxyphenyl)-2-phenyl-3-(piperidin-1-yl)-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942333
|
6-(4-methoxyphenyl)-5-methyl-2-phenyl-3-(1H-pyrrol-3-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C24H20N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944470
|
6-(4-methoxyphenyl)-5-((5-nitropyridin-2-yl)amino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22N6O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944472
|
5-((5-aminopyrazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944473
|
5-((1H-1,2,4-triazol-3-yl)amino)-6-(4-hydroxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H19N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944478
|
3-(cyclohex-1-en-1-yl)-5-(hydroxymethyl)-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H24N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944479
|
2-(4-hydroxyphenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H20N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944481
|
5-(((1H-1,2,4-triazol-3-yl)amino)methyl)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944482
|
3-cyclohex-1-en-1-yl-1-(methoxymethyl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(1H)-one
Show/Hide
|
C28H29N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944483
|
6-cyclopropyl-5-methyl-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0944950
|
6-(4-methoxyphenyl)-5-(1-methyl-1H-imidazol-2-ylamino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H24N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944964
|
5-((5-amino-1,3,4-thiadiazol-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H21N7O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948217
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyrimidin-5-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948232
|
5-((3-aminopyrazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948233
|
5-((1,3,5-triazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948234
|
5-((4-amino-1,3,5-triazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H22N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948235
|
N-(7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)propionamide
Show/Hide
|
C30H23N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0948244
|
6-(2-methylbenzo[d]thiazol-6-yl)-2,3-diphenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H22N6OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948246
|
5-(hydroxymethyl)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H21N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948247
|
5-(aminomethyl)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948248
|
1-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)urea
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948249
|
5-methyl-3-phenyl-2-(1H-pyrazol-3-yl)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H18N6O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948250
|
(4-(3-cyclohexenyl-5-methyl-7-oxo-2-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)phenoxy)methyl dihydrogen phosphate
Show/Hide
|
C26H26N3O6P
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0948252
|
6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carbonitrile
Show/Hide
|
C26H18N4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0948253
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyridazin-3-ylamino)pyrazol[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951424
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyridin-3-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C30H23N5O2
|
1
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| 1 |
IC50 < 100 nM
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CP0951425
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5-((5-fluoropyridin-2-yl)amino)-6(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
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C30H22FN5O2
|
1
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| 1 |
IC50 < 100 nM
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CP0951427
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2-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-ylamino)pyrimidine-5-carbonitrile
Show/Hide
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C30H21N7O2
|
1
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| 1 |
IC50 < 100 nM
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CP0951428
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5-((1H-imidazol-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C28H22N6O2
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1
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| 1 |
IC50 < 100 nM
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CP0951429
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3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-3-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C30H27N5O2
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1
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| 1 |
IC50 < 100 nM
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CP0951433
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5-(isoxazol-3-ylamino)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C30H20N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0951434
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3-cyclohexenyl-2-phenyl-5-(pyridin-2-ylamino)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C32H26N6O
|
1
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| 1 |
IC50 < 100 nM
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CP0951471
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(E)-2-hydroxy-1-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)guanidine
Show/Hide
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C26H22N6O3
|
1
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| 1 |
IC50 < 100 nM
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CP0951473
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3-(3,4-dihydro-2H-pyran-6-yl)-5-methyl-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H22N4O2
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1
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| 1 |
IC50 < 100 nM
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CP0951474
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3-(cyclohex-1-en-1-yl)-5-(hydroxymethyl)-2-phenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H23N5O2
|
1
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| 1 |
IC50 < 100 nM
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CP0951476
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6-(5-methyl-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)quinoline-2-carboxylic acid
Show/Hide
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C29H20N4O3
|
1
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| 1 |
IC50 < 100 nM
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CP0954116
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3-(cyclohex-1-en-1-yl)-5-methyl-2-phenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H23N5O
|
1
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| 1 |
IC50 < 100 nM
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CP0954117
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5-(aminomethyl)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C26H22N4O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954170
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6-(benzofuran-5-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H19N3O2
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1
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| 1 |
IC50 = 100 nM
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CP0954171
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3-(3,6-dihydro-2H-pyran-4-yl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C25H23N3O3
|
1
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| 1 |
IC50 < 100 nM
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CP0954172
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5-(aminomethyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C28H21N5O
|
1
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| 1 |
IC50 < 100 nM
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CP0954173
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5-methyl-2,3-diphenyl-6-(quinazolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H19N5O
|
1
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| 1 |
IC50 < 100 nM
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CP0954174
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5-methyl-6-(1-methyl-1H-benzo[d]imidazol-6-yl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H21N5O
|
1
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| 1 |
IC50 < 100 nM
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CP0954175
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6-(4-hydroxy-3-methoxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C26H21N3O3
|
1
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| 1 |
IC50 < 100 nM
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|
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CP0954176
|
5-(hydroxymethyl)-4-methyl-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H22N4O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954177
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4-(5-methyl-7-oxo-2-phenyl-3-(piperidin-1-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)benzamide
Show/Hide
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C25H25N5O2
|
1
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| 1 |
IC50 = 100 nM
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CP0954178
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3-(3,3-difluoropyrrolidin-1-yl)-5-methyl-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C26H21F2N5O
|
1
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| 1 |
IC50 = 100 nM
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CP0954180
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5-((6-chloropyridazin-3-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H21ClN6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954181
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6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyrazin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H22N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954182
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5-((3-hydroxypyrazin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H22N6O3
|
1
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| 1 |
IC50 < 100 nM
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CP0954648
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6-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)amino)nicotinonitrile
Show/Hide
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C31H22N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954649
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5-((6-fluoropyridin-2-yl)amino)-6(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C30H22FN5O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954650
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6-(4-methoxyphenyl)-5-((4-(methylamino)-1,3,5-triazin-2-yl)amino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H24N8O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954651
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5-((4,5-dihydrothiazol-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C28H23N5O2S
|
1
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| 1 |
IC50 < 100 nM
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CP0954652
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3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyrimidin-4-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H26N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954653
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5-(3-cyclohexenyl-6-(4-methoxyphenyl)-7-oxo-2-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-ylamino)pyrazine-2-carbonitrile
Show/Hide
|
C30H25N7O2
|
1
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| 1 |
IC50 < 100 nM
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CP0954654
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3-(3-chlorophenyl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
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CP0954672
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5-(aminomethyl)-3-(cyclohex-1-en-1-yl)-6-(4-hydroxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H24N4O2
|
1
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| 1 |
IC50 < 100 nM
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CP0955180
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6-((6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5yl)amino)picolinonitrile
Show/Hide
|
C31H22N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0955181
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2-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-ylamino)isonicotinonitrile
Show/Hide
|
C31H22N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0955182
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5-((1,2,4-triazin-5-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N7O2
|
1
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| 1 |
IC50 < 100 nM
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CP0955183
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5-((2H-1,2,3-triazol-4-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H21N7O2
|
1
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| 1 |
IC50 < 100 nM
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CP0955184
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5-(aminomethyl)-3-(cyclohex-1-en-1-yl)-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H25N5O
|
1
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| 1 |
IC50 < 100 nM
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CP0955185
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5-(aminomethyl)-3-(cyclohex-1-en-1-yl)-2-phenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H24N6O
|
1
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| 1 |
IC50 < 100 nM
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CP0955186
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2,2,2-trifluoro-N-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)acetamide
Show/Hide
|
C30H20F3N5O2
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1
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| 1 |
IC50 < 100 nM
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CP0955187
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5-hydroxy-6-(4-methoxyphenyl)-4-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H21N3O3
|
1
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| 1 |
IC50 < 100 nM
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CP0955188
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5-((methylamino)methyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N5O
|
1
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| 1 |
IC50 < 100 nM
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|
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CP0955189
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2-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)acetonitrile
Show/Hide
|
C27H20N4O2
|
1
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| 1 |
IC50 = 100 nM
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CP0955191
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6-(6-methoxypyridin-3-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H20N4O2
|
1
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| 1 |
IC50 = 100 nM
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CP0955192
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5-((1H-tetrazol-1-yl)methyl)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H21N7O2
|
1
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| 1 |
IC50 = 100 nM
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CP0958054
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5-((1,2,4-thiadiazol-5-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H24N6O2S
|
1
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| 1 |
IC50 < 100 nM
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CP0959017
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5-(hydroxymethyl)-6-(4-methoxyphenyl)-4-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H23N3O3
|
1
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| 1 |
IC50 < 100 nM
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CP0959018
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5-methyl-2-phenyl-3-(piperidin-1-yl)-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H24N6O
|
1
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| 1 |
IC50 < 100 nM
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CP0959019
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3-(3-hydroxycyclohex-1-enyl)-5-methyl-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H24N4O2
|
1
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| 1 |
IC50 < 100 nM
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CP0959323
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5-((1H-imidazol-4-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H22N6O2
|
1
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| 1 |
IC50 < 100 nM
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CP0959324
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6-(4-methoxyphenyl)-5-((5-methyl-1,3,4-thiadiazol-2-yl)amino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H22N6O2S
|
1
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| 1 |
IC50 < 100 nM
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CP0963548
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5-((4-hydroxypyridin-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H23N5O3
|
1
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| 1 |
IC50 < 100 nM
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CP0963549
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5-(3-hydroxypyridin-2-ylamino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H23N5O3
|
1
|
| 1 |
IC50 < 100 nM
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CP0963550
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3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C26H25N3O2
|
1
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| 1 |
IC50 < 100 nM
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CP0963551
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3-(5,6-dihydro-2H-pyran-3-yl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H23N3O3
|
1
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| 1 |
IC50 < 100 nM
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CP0963552
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6-(3-fluoro-4-hydroxyphenyl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H18FN3O2
|
1
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| 1 |
IC50 < 100 nM
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|
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CP0963553
|
5-((1H-pyrazol-1-yl)methyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H22N6O
|
1
|
| 1 |
IC50 = 100 nM
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|
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CP0963554
|
5-methyl-2,3-diphenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H19N5O
|
1
|
| 1 |
IC50 = 100 nM
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CP0964631
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6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H21N3O3
|
1
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| 1 |
IC50 < 100 nM
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CP0964632
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3-(cyclohex-1-en-1-yl)-6-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-(hydroxymethyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H25N3O4
|
1
|
| 1 |
IC50 < 100 nM
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|
|
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CP0964637
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(phenylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H24N4O2
|
1
|
| 1 |
IC50 = 100 nM
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CP0964709
|
1-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)imidazolidine-2,4-dione
Show/Hide
|
C31H22N6O3
|
1
|
| 1 |
IC50 = 100 nM
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|
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CP0964718
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5-hydroxy-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H18N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
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CP0966402
|
5-(isoxazol-3-ylamino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O3
|
1
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| 1 |
IC50 < 100 nM
|
|
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CP0966403
|
5-((1,2,4-triazin-5-yl)amino)-3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H25N7O2
|
1
|
| 1 |
IC50 < 100 nM
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|
|
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CP0966404
|
2-hydroxy-N-(7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)acetamide
Show/Hide
|
C29H21N5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0966405
|
3-cyclohexenyl-5-(isoxazol-3-ylamino)-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H24N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0968280
|
5-(6-(4-methoxyphenyl)-7-oxo-2,3-diphenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-ylamino)pyrazine-2-carbonitrile
Show/Hide
|
C30H21N7O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0968281
|
5-(isoxazol-5-ylamino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0968282
|
5-((1,3,4-thiadiazol-2-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H20N6O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
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CP0968283
|
5-((1H-pyrrolo[2,3-c]pyridin-5-yl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C32H24N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0968284
|
5-(1H-pyrazol-3-ylamino)-3-cyclohexenyl-2-phenyl-6-(quinoxalin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H24N8O
|
1
|
| 1 |
IC50 < 100 nM
|
|
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CP0968285
|
3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-(pyridin-2-yl)-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H26N6O2
|
1
|
| 1 |
IC50 < 100 nM
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CP0968286
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2-hydroxy-N-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)acetamide
Show/Hide
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C30H23N5O3
|
1
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| 1 |
IC50 < 100 nM
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CP0968287
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N-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)acetamide
Show/Hide
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C30H23N5O2
|
1
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| 1 |
IC50 < 100 nM
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CP0968288
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2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H18N4O
|
1
|
| 1 |
IC50 < 100 nM
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CP0968289
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6-(3-hydroxy-2-methylquinolin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H22N4O2
|
1
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| 1 |
IC50 < 100 nM
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CP0968290
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N-(2-hydroxyethyl)-7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxamide
Show/Hide
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C30H23N5O3
|
1
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| 1 |
IC50 = 100 nM
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CP0968291
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6-(4-aminoquinazolin-6-yl)-5-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H20N6O
|
1
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| 1 |
IC50 = 100 nM
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CP0968805
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5-(2-hydroxypyrimidin-4-ylamino)-6-(4-methoxyphenyl)-2,3-diphenyl-pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H22N6O3
|
1
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| 1 |
IC50 < 100 nM
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CP0968806
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6-(4-methoxyphenyl)-5-((6-methoxypyridazin-3-yl)amino)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C30H24N6O3
|
1
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| 1 |
IC50 < 100 nM
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CP0968807
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6-(4-methoxyphenyl)-2,3-diphenyl-5-(thiazol-4-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C28H21N5O2S
|
1
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| 1 |
IC50 < 100 nM
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CP0969152
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3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridazin-3-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C29H26N6O2
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1
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| 1 |
IC50 < 100 nM
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CP0969153
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2,3-diphenyl-5-(pyridin-2-ylamino)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C32H22N6O
|
1
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| 1 |
IC50 < 100 nM
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CP0969154
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3-(cyclohex-1-en-1-yl)-6-(4-hydroxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C25H23N3O2
|
1
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| 1 |
IC50 < 100 nM
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CP0969155
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3-(4,4-difluorocyclohex-1-en-1-yl)-5-methyl-2-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C28H22F2N4O
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1
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| 1 |
IC50 < 100 nM
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CP0969156
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3-(3,3-difluoropyrrolidin-1-yl)-6-(4-methoxyphenyl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C24H22F2N4O2
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1
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| 1 |
IC50 < 100 nM
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CP0969157
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5-((2-hydroxyethyl)amino)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H24N4O3
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1
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| 1 |
IC50 < 100 nM
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CP0969158
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4-(3-(cyclohex-1-en-1-yl)-5-methyl-7-oxo-2-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)phenyl dihydrogen phosphate
Show/Hide
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C25H24N3O5P
|
1
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| 1 |
IC50 < 100 nM
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CP0969159
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5-methyl-6-morpholino-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C22H27N5O2
|
1
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| 1 |
IC50 = 100 nM
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CP0969160
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5-((2H-tetrazol-2-yl)methyl)-6-(4-methoxyphenyl)-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
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C27H21N7O2
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1
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| 1 |
IC50 = 100 nM
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CP0466410
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4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(2,2,2-trifluoroethoxy)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C24H16F5N5O3
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1
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| 1 |
IC50 < 100 nM
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CP0466411
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6-(2,2-difluoroethoxy)-4-[4-(difluoromethoxy)phenyl]-2-(2,3-dihydro-1-benzofuran-5-yl)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C24H17F4N3O4
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1
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| 1 |
IC50 < 100 nM
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CP0487495
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2-(1,3-benzothiazol-6-yl)-6-(2,2-difluoroethoxy)-4-[4-(difluoromethoxy)phenyl]pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C23H14F4N4O3S
|
1
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| 1 |
IC50 < 100 nM
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CP0507631
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6-(2,2-difluoroethoxy)-4-(6-methoxypyridin-3-yl)-2-(2-methylindazol-5-yl)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C23H18F2N6O3
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1
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| 1 |
IC50 < 100 nM
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CP0553141
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4-(4-chlorophenyl)-2-(2-methylindazol-5-yl)-6-(2,2,2-trifluoroethoxy)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C23H15ClF3N5O2
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1
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| 1 |
IC50 < 100 nM
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CP0556540
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4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(2,2,2-trifluoroethylsulfanyl)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C24H16F5N5O2S
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1
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| 1 |
IC50 < 100 nM
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CP0556615
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4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(3,3,3-trifluoropropoxy)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C25H18F5N5O3
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1
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| 1 |
IC50 < 100 nM
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CP0568372
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6-(2,2-difluoroethoxy)-4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C24H17F4N5O3
|
1
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| 1 |
IC50 < 100 nM
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CP0569312
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6-ethoxy-4-(4-methoxyphenyl)-2-(2-methylindazol-5-yl)pyrido[3,2-c]pyridazin-3-one
Show/Hide
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C24H21N5O3
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1
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| 1 |
IC50 < 100 nM
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CP0569313
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6-(2,2-difluoroethoxy)-4-[4-(difluoromethoxy)phenyl]-2-[2-methyl-3-(trideuteriomethoxy)indazol-5-yl]pyrido[3,2-c]pyridazin-3-one
Show/Hide
|
C25H19F4N5O4
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1
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| 1 |
IC50 < 100 nM
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CP0579193
|
6-(4-hydroxyphenyl)-4,5-dimethyl-2-phenyl-3-piperidin-1-ylpyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
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C25H26N4O2
|
1
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| 1 |
IC50 = 102 nM
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CP0558823
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5-methyl-2-phenyl-3-piperidin-1-yl-6-(1,3-thiazol-4-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
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C21H21N5OS
|
2
|
| 1 |
IC50 = 158 nM
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| 2 |
IC50 = 1000 nM
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CP0579347
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2-(cyclopropylmethylamino)-1'-[(2-fluorophenyl)methyl]-6-(4-methoxyphenyl)-4-methylspiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C29H32FN5O2
|
1
|
| 1 |
IC50 = 250 nM
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CP0423494
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3-(cyclohexen-1-yl)-5-methyl-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
IC50 = 260 nM
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CP0567416
|
CHEMBL4877839
Show/Hide
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C18H20N4O
|
1
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| 1 |
IC50 = 260 nM
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CP0558820
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2,3-diphenyl-5-(1H-pyrazol-5-ylamino)-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C21H16N6O
|
1
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| 1 |
IC50 = 270 nM
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CP0574239
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2-(cyclopropylmethylamino)-1'-[(2-fluorophenyl)methyl]-6-(4-methoxyphenyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C28H30FN5O2
|
1
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| 1 |
IC50 = 320 nM
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CP0576035
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8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-(3,3,3-trifluoropropylamino)pyrido[4,3-d]pyrimidin-7-one
Show/Hide
|
C23H18BrF3N4O2
|
1
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| 1 |
IC50 = 325 nM
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CP0576032
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1'-[(2-amino-1,3-thiazol-5-yl)methyl]-2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C25H29N7O2S
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1
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| 1 |
IC50 = 410 nM
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CP0579348
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2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(thiophen-3-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C26H29N5O2S
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1
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| 1 |
IC50 = 510 nM
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CP0579500
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2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(1,2-oxazol-3-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C25H28N6O3
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1
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| 1 |
IC50 = 530 nM
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CP0568860
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2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(1,3-thiazol-4-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C25H28N6O2S
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1
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| 1 |
IC50 = 610 nM
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CP0579708
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3-cyclohexyl-5-methyl-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H21N3O
|
1
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| 1 |
IC50 = 660 nM
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CP0558822
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3-cyclopentyl-5-methyl-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C18H19N3O
|
1
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| 1 |
IC50 = 680 nM
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CP0570424
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2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(1H-pyrazol-5-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C25H29N7O2
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1
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| 1 |
IC50 = 690 nM
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CP0869005
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5-methyl-2-(4-nitrophenyl)-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H19N5O3
|
1
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| 1 |
IC50 = 1000 nM
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CP0884290
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5-methyl-6-(2-oxo-1,2-dihydropyridin-4-yl)-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C23H23N5O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0884292
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2-(2-chloropyridin-4-yl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H18ClN5O
|
1
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| 1 |
IC50 = 1000 nM
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CP0901583
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2-(2-methoxypyridin-4-yl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0902495
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4-(2-(1H-tetrazol-1-yl)ethyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C30H22N8O
|
1
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| 1 |
IC50 = 1000 nM
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CP0904658
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5-((2-oxoimidazolidin-1-yl)methyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H24N6O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0904665
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6-(4-methoxyphenyl)-5-phenoxy-2,3-diphenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C31H23N3O3
|
1
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| 1 |
IC50 = 1000 nM
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CP0909745
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2-(3-chlorophenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H19ClN4O
|
1
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| 1 |
IC50 = 1000 nM
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CP0909746
|
2-(4-chlorophenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H19ClN4O
|
1
|
| 1 |
IC50 = 1000 nM
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CP0909747
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5-methyl-3-phenyl-2-(pyridin-4-yl)-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C27H19N5O
|
1
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| 1 |
IC50 = 1000 nM
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CP0913642
|
2-(4-methoxyphenyl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H22N4O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0915921
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2-(6-methoxypyridin-3-yl)-5-methyl-3-phenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C28H21N5O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0944484
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N-(4-(5-methyl-7-oxo-2-phenyl-3-(piperidin-1-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)phenyl)acetamide
Show/Hide
|
C26H27N5O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0944485
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3-((7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)methyl)imidazolidine-2,4-dione
Show/Hide
|
C31H22N6O3
|
1
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| 1 |
IC50 = 1000 nM
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CP0944486
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N-((1H-pyrazol-3-yl)methyl)-7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxamide
Show/Hide
|
C32H23N7O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0944487
|
6-(4-methoxyphenyl)-2,3-diphenyl-5-(pyridazin-3-yloxy)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H21N5O3
|
1
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| 1 |
IC50 = 1000 nM
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CP0948251
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5-methyl-6-(4-(methylsulfonyl)phenyl)-2-phenyl-3-(piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C25H26N4O3S
|
1
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| 1 |
IC50 = 1000 nM
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CP0955190
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N-(7-oxo-2,3-diphenyl-6-(quinolin-6-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)cyclopropanecarboxamide
Show/Hide
|
C31H23N5O2
|
1
|
| 1 |
IC50 = 1000 nM
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CP0966408
|
4-(2-aminoethyl)-2,3-diphenyl-6-(quinolin-6-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Show/Hide
|
C29H23N5O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0423493
|
CHEMBL4878283
Show/Hide
|
C18H17N3O
|
1
|
| 1 |
IC50 = 1140 nM
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CP0423491
|
5-methyl-2,3-diphenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H15N3O
|
1
|
| 1 |
IC50 = 1500 nM
|
|
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CP0568031
|
CHEMBL4866030
Show/Hide
|
C17H13N3O2
|
1
|
| 1 |
IC50 = 1500 nM
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CP0423496
|
2-(3-fluorophenyl)-5-methyl-3-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C19H14FN3O
|
1
|
| 1 |
IC50 = 1900 nM
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CP0568347
|
2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(1H-pyrrol-3-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
Show/Hide
|
C26H30N6O2
|
1
|
| 1 |
IC50 = 2010 nM
|
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CP0574623
|
8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[methyl(2,2,2-trifluoroethyl)amino]pyrido[4,3-d]pyrimidin-7-one
Show/Hide
|
C23H18BrF3N4O2
|
1
|
| 1 |
IC50 = 3310 nM
|
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CP0423492
|
3-(furan-2-yl)-5-methyl-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C17H13N3O2
|
1
|
| 1 |
IC50 = 3660 nM
|
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CP0563605
|
5-ethyl-2,3-diphenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
IC50 = 3660 nM
|
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CP0423499
|
N-(7-oxo-2,3-diphenyl-1H-pyrazolo[1,5-a]pyrimidin-5-yl)acetamide
Show/Hide
|
C20H16N4O2
|
1
|
| 1 |
IC50 = 4110 nM
|
|
|
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CP0563604
|
CHEMBL4862694
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
IC50 = 7100 nM
|
|
|
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CP0547278
|
N-(cyclopropylmethyl)-1'-[(2-fluorophenyl)methyl]-4-methylspiro[5,7-dihydropyrano[4,3-d]pyrimidine-8,3'-pyrrolidine]-2-amine
Show/Hide
|
C22H27FN4O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
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CP0568182
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2-(cyclopropylmethylamino)-6-(4-methoxyphenyl)-1'-(1H-pyrazol-4-ylmethyl)spiro[5H-pyrido[4,3-d]pyrimidine-8,3'-pyrrolidine]-7-one
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C25H29N7O2
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1
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| 1 |
IC50 = 7830 nM
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CP0423495
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2-(3-hydroxyphenyl)-5-methyl-3-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C19H15N3O2
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1
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| 1 |
IC50 = 12200 nM
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CP0558738
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5-anilino-2,3-diphenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C24H18N4O
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1
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| 1 |
IC50 = 16600 nM
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CP0423486
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5-methyl-3-phenyl-2-(1H-pyrazol-4-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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C16H13N5O
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1
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| 1 |
IC50 = 50100 nM
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CP0423487
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CHEMBL4858279
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C16H12N4OS
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1
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| 1 |
IC50 = 78800 nM
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