Brief Information of the Compound and Protein
Compound Name
5-methyl-2-phenyl-3-piperidin-1-yl-6-(1,3-thiazol-4-yl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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Canonical SMILES
Cc1[nH]c2c(N3CCCCC3)c(nn2c(=O)c1-c1cscn1)-c1ccccc1
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Compound Formula C21H21N5OS
Compound Structure
Protein Name
S-adenosylmethionine synthase isoform type-2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P31153
Gene Name
MAT2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 158 nM
   TI
   LI
   LO
   TS
2
IC50 = 1000 nM
   TI
   LI
   LO
   TS