Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(difluoromethoxy)phenyl]-2-(2-methylindazol-5-yl)-6-(2,2,2-trifluoroethylsulfanyl)pyrido[3,2-c]pyridazin-3-one
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 PubChem ID
CID: 153629441
Canonical SMILES
Cn1cc2cc(ccc2n1)-n1nc2ccc(SCC(F)(F)F)nc2c(-c2ccc(OC(F)F)cc2)c1=O
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Compound Formula C24H16F5N5O2S
Compound Structure
Protein Name
 Protein Info 
S-adenosylmethionine synthase isoform type-2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P31153
Gene Name
MAT2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 100 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 < 100 nM
   TI
   LI
   LO
   TS