5-cyclopropyl-3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-methyl-3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-4-(pyridin-2-ylmethyl)morpholin-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-(3,4-dihydro-1H-isochromen-1-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-4-[(4-ethyl-1,3-thiazol-2-yl)methyl]morpholin-2-yl]methyl]-5-methyltriazolo[4,5-d]pyrimidin-7-amine

3-[(3-tert-butyl-1H-pyrazol-5-yl)methyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(3-cyclopropyl-1H-pyrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-(phenylsulfanylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-(2-methyl-1,3-thiazol-4-yl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

5-[(3-fluorophenoxy)methyl]-3-(oxolan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-thiophen-2-yltriazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-(2,3-dihydro-1-benzofuran-5-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-4-[(3,5-difluorophenyl)methyl]morpholin-2-yl]methyl]-5-methyltriazolo[4,5-d]pyrimidin-7-amine

tert-butyl 2-[(7-amino-5-cyclopropyltriazolo[4,5-d]pyrimidin-3-yl)methyl]piperidine-1-carboxylate

5-ethyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[[1-(4-methylpyrimidin-2-yl)piperidin-3-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[[(2R)-4-(pyrimidin-2-ylmethyl)morpholin-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[[(2R)-oxolan-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(7-methylimidazo[1,2-a]pyridin-2-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(2-methyl-3,4-dihydro-1H-isoquinolin-3-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[1-(1H-indol-5-yl)ethyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-propyltriazolo[4,5-d]pyrimidin-7-amine

3-[(4-benzylmorpholin-2-yl)methyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-amine

2-[(7-amino-5-cyclopropyltriazolo[4,5-d]pyrimidin-3-yl)methyl]-3H-quinazolin-4-one

5-methyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[1-(6-methylpyridin-2-yl)propan-2-yl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(2-phenyltriazol-4-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(8-methylimidazo[1,2-a]pyridin-2-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(3-phenyl-1H-1,2,4-triazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-benzyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

methyl 2-[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]acetate

5-(3-methylbutyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[(1S)-1-cyclohexylethyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-amine

2-[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]acetic acid

5-cyclopropyl-3-[[4-(trifluoromethyl)phenyl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[2-(4-methyl-1,3-thiazol-5-yl)ethyl]triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-(propan-2-ylsulfonylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-(furan-2-yl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[(4-chlorophenyl)methyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-(thiophen-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-benzyl-N-(1-phenyl-2-piperidin-1-ylethyl)-5-propan-2-yltriazolo[4,5-d]pyrimidin-7-amine

7-amino-3-[(4-methoxyphenyl)methyl]triazolo[4,5-d]pyrimidine-5-carbonitrile

5-(methoxymethyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[[(3R)-1-(5-ethylpyrimidin-2-yl)pyrrolidin-3-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(2-ethyl-1,3-thiazol-4-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]methyl acetate

5-cyclopropyl-3-[2-(furan-2-ylmethylsulfanyl)ethyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(1-propan-2-ylpyrazol-4-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-(oxan-3-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-phenyltriazolo[4,5-d]pyrimidin-7-amine

5-(methylsulfanylmethyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

2-[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]acetonitrile

5-(2-methylpropyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[[(3R)-1-(1,3-thiazol-2-ylmethyl)pyrrolidin-3-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[(4-phenyloxan-4-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-butyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclohexyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclobutyl-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-(oxolan-2-yl)triazolo[4,5-d]pyrimidin-7-amine

7-amino-3-[(4-methoxyphenyl)methyl]triazolo[4,5-d]pyrimidine-5-carboxamide

3-(oxan-2-ylmethyl)-5-(thiophen-3-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-(methoxymethyl)-3-[[(2R)-oxolan-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

5-(cyclopropylmethyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-5-pyridin-3-yltriazolo[4,5-d]pyrimidin-7-amine

5-(5-methyl-1,2-oxazol-3-yl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

6-[(7-amino-5-cyclopropyltriazolo[4,5-d]pyrimidin-3-yl)methyl]-4-butylmorpholin-3-one

5-cyclopropyl-3-[(7-methylimidazo[1,2-a]pyrimidin-2-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine

5-(imidazol-1-ylmethyl)-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

5-cyclopropyl-3-[2-(1-methylpyrazol-4-yl)ethyl]triazolo[4,5-d]pyrimidin-7-amine

N',N'-dimethyl-N-[3-(oxan-2-ylmethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-yl]ethane-1,2-diamine

[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]methanol

5-cyclopropyl-3-(oxan-4-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

2-[7-amino-3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]acetamide

3-(oxan-2-ylmethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-4-ylmethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[(1-benzylpiperidin-3-yl)methyl]-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-N-(oxolan-2-ylmethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[(5-methylfuran-2-yl)methyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[2-(furan-2-yl)ethyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-(1-methoxypropan-2-yl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[(5-ethylpyridin-2-yl)methyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N',N'-dimethyl-N-[3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-yl]ethane-1,2-diamine

methyl 2-[[3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-yl]amino]acetate

N-[(4-methoxyphenyl)methyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-N-(thian-4-yl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N,N,5-trimethyl-3-[[(2R)-oxolan-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine

N-cyclohexyl-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[(4-methylphenyl)methyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-(oxolan-2-ylmethyl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N',N'-dimethyl-N-[3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-yl]propane-1,3-diamine

3-[[(2R)-oxolan-2-yl]methyl]-N-(2-phenoxyethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-cyclopropyl-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-N-(2-pyridin-4-ylethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-methyl-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-(3-methylbutyl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-N-(2-pyrazol-1-ylethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[(5-methylpyrazin-2-yl)methyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-[2-(3-fluorophenyl)ethyl]-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-(3-methoxypropyl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-[[(2R)-oxolan-2-yl]methyl]-N-(3-phenylpropyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

6-cyclopropyl-1-(oxolan-2-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine

N-(2,3-dihydro-1H-inden-2-yl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-cycloheptyl-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

N-(2-cyclopentylethyl)-3-[[(2R)-oxolan-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

3-(oxan-2-ylmethyl)-N-(pyridin-3-ylmethyl)-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine

2-cyclopropyl-9-[[(2R)-oxolan-2-yl]methyl]purin-6-amine