Brief Information of the Compound and Protein
Compound Name
3-[[(2R)-4-[(3,5-difluorophenyl)methyl]morpholin-2-yl]methyl]-5-methyltriazolo[4,5-d]pyrimidin-7-amine
    Show/Hide
PubChem ID
CID: 52939013
SID: 163451770
Canonical SMILES
Cc1nc(N)c2nnn(C[C@H]3CN(Cc4cc(F)cc(F)c4)CCO3)c2n1
    Show/Hide
Compound Formula C17H19F2N7O
Compound Structure
Protein Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 8
>
Phosphodiesterase 8B
Uniprot ID
O95263
Gene Name
PDE8B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS