Brief Information of the Compound and Protein
Compound Name
5-cyclopropyl-3-[[(3R)-1-(1,3-thiazol-2-ylmethyl)pyrrolidin-3-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine
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PubChem ID
CID: 70682561
SID: 163451767
Canonical SMILES
Nc1nc(nc2n(C[C@@H]3CCN(Cc4nccs4)C3)nnc12)C1CC1
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Compound Formula C16H20N8S
Compound Structure
Protein Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Protein Classification
Enzyme
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Phosphodiesterase
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Phosphodiesterase 8
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Phosphodiesterase 8B
Uniprot ID
O95263
Gene Name
PDE8B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 206 nM
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