Brief Information of the Compound and Protein
Compound Name
5-cyclopropyl-3-[(2-ethyl-1,3-thiazol-4-yl)methyl]triazolo[4,5-d]pyrimidin-7-amine
    Show/Hide
PubChem ID
CID: 70682560
SID: 163451633
Canonical SMILES
CCc1nc(Cn2nnc3c(N)nc(nc23)C2CC2)cs1
    Show/Hide
Compound Formula C13H15N7S
Compound Structure
Protein Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 8
>
Phosphodiesterase 8B
Uniprot ID
O95263
Gene Name
PDE8B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS