| Compound ID |
Compound Name |
Compound Formula |
|
CP0545821
|
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-phenylurea
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|
C18H17F2N3O3
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0546958
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,2-oxazol-3-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C20H16ClF2N3O3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0395312
|
1-(3-tert-butyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-chlorophenyl)urea
Show/Hide
|
C21H23ClN4O2
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0374845
|
1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Show/Hide
|
C24H25N5O2S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0525163
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-iodophenyl)urea
Show/Hide
|
C18H17IN4O2
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0569103
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O3
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0446518
|
2-ethyl-1-[(3R)-1-[(5-methoxy-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0580015
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O2S
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0580225
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(2-fluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H16ClFN4O3
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0965302
|
(3R,4R)-3-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C17H13ClF2N4O2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0541744
|
1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Show/Hide
|
C19H22N6O2S
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0259831
|
1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(propan-2-yl)-2,3-dihydro-1H-pyrazol-4-yl]urea
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0374827
|
1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C24H22F3N5O2
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0579427
|
(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-3-[[5-[4-(trifluoromethoxy)phenyl]-1,3,4-oxadiazol-2-yl]amino]pyrrolidin-2-one
Show/Hide
|
C20H15F5N4O4
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0499716
|
1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C23H22ClN5O2
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0522966
|
1-(3-fluoro-4-methylphenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C21H23FN4O2
|
1
|
| 1 |
EC50 = 81 nM
|
|
|
|
CP0532343
|
1-(3-tert-butyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C22H25FN4O2
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
|
CP0395322
|
1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C18H17BrN4O2
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0529099
|
1-(2-ethyl-3-isopropyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C22H25FN4O2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0542272
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C19H17F3N4O2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0969958
|
(3R,4R)-3-(5-chloro-1H-benzo[d]imidazol-2-yl)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C18H14ClF2N3O2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0509978
|
2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl}-1H-1,3-benzodiazole
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0506065
|
1-(4-chlorophenyl)-3-(3-ethyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C19H19ClN4O2
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0541743
|
1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C19H19F3N6O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0574646
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H17ClN4O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0393825
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Show/Hide
|
C19H20N4O2S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0496722
|
1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C18H19ClN6O2
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0578828
|
(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-3-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]pyrrolidin-2-one
Show/Hide
|
C19H16F2N4O3
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0580081
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,3-oxazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C20H16ClF2N3O3
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0399583
|
2-ethyl-1-[(3R)-1-[(5-ethyl-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0442117
|
1-(3-ethyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C20H21FN4O2
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0252495
|
1-(4-chlorophenyl)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)urea
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0522965
|
1-(4-chlorophenyl)-3-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C17H20ClN5O2S
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0969952
|
(3R,4R)-3-(1H-benzo[d]imidazol-2-yl)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C18H15F2N3O2
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0424810
|
2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-1H-1,3-benzodiazole
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0523092
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-ethylphenyl)urea
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
EC50 = 770 nM
|
|
|
|
CP0457626
|
1-[(3R)-1-[(5-bromo-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-2-ethyl-1H-1,3-benzodiazole
Show/Hide
|
C22H21BrN4O
|
1
|
| 1 |
EC50 = 810 nM
|
|
|
|
CP0424809
|
1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-2-(2-methylpropyl)-1H-1,3-benzodiazole
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
EC50 = 830 nM
|
|
|
|
CP0579426
|
(3S,4R)-3-[[5-(4-chloro-2-fluorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H14ClF3N4O3
|
1
|
| 1 |
EC50 = 840 nM
|
|
|
|
CP0393823
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(3-fluoro-4-methylphenyl)urea
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
EC50 = 980 nM
|
|
|
|
CP0486809
|
1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-2-methyl-1H-1,3-benzodiazole
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 1020 nM
|
|
|
|
CP0407255
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-p-tolylurea
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0968206
|
(3S,4R)-3-((1H-benzo[d]imidazol-2-yl)amino)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0541742
|
1-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Show/Hide
|
C18H20F3N5O2S
|
1
|
| 1 |
EC50 = 1470 nM
|
|
|
|
CP0440710
|
2-ethyl-1-[(3R)-1-[(5-fluoro-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole
Show/Hide
|
C22H21FN4O
|
1
|
| 1 |
EC50 = 1490 nM
|
|
|
|
CP0440811
|
1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-2-(trifluoromethyl)-1H-1,3-benzodiazole
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
EC50 = 1520 nM
|
|
|
|
CP0447652
|
2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole
Show/Hide
|
C22H23N5O2
|
1
|
| 1 |
EC50 = 1870 nM
|
|
|
|
CP0579428
|
(3S,4R)-3-[[3-(4-chlorophenyl)-1,2-oxazol-5-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C20H16ClF2N3O3
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0970277
|
(3R,4R)-3-(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C17H13ClF2N4O2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0580014
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O3
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0440810
|
1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-2-phenyl-1H-1,3-benzodiazole
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
EC50 = 2710 nM
|
|
|
|
CP0449432
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H20N4O3
|
1
|
| 1 |
EC50 = 2730 nM
|
|
|
|
CP0446515
|
2-ethyl-1-[(3S)-1-[(5-methoxy-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0546956
|
(3S,4R)-3-[[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O3
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0523091
|
1-(4-cyanophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C19H17N5O2
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0580080
|
(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-3-[[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]amino]pyrrolidin-2-one
Show/Hide
|
C20H18F2N4O4
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0502962
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-fluorophenyl)urea
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
EC50 = 4850 nM
|
|
|
|
CP0424807
|
1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl}-1H-1,3-benzodiazole
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
EC50 = 5100 nM
|
|
|
|
CP0395311
|
1-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Show/Hide
|
C18H23N5O2S2
|
1
|
| 1 |
EC50 = 5130 nM
|
|
|
|
CP0274397
|
1-(benzo[d][1,3]dioxol-5-yl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C19H18N4O4
|
1
|
| 1 |
EC50 = 5880 nM
|
|
|
|
CP0393824
|
1-(2-chlorophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424808
|
1-(2-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(propan-2-yl)-2,3-dihydro-1H-pyrazol-4-yl]urea
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0499715
|
1-(1,5-dimethyl-3-oxo-2-phenylpyrazolidin-4-yl)-3-(4-iodophenyl)-1,3-dimethylurea
Show/Hide
|
C20H23IN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0502562
|
1-(3-chlorophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0515765
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-fluoro-3-methylphenyl)urea
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0523090
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(thiazol-2-yl)urea
Show/Hide
|
C15H15N5O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0526722
|
1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-phenylurea
Show/Hide
|
C18H18N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0567905
|
(3S,4R)-3-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0569104
|
(3S,4R)-3-[[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C19H15ClF2N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0579430
|
(3S,4R)-3-[[5-(4-chlorophenyl)-1-methylpyrazol-3-yl]amino]-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C21H19ClF2N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0953133
|
(3R,4R)-3-(4-chloro-1H-benzo[d]imidazol-2-yl)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C18H14ClF2N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0969959
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(3S,4R)-3-((5-(4-chlorophenyl)-1H-pyrazol-3-yl)amino)-4-(2,6-difluoro-4-methoxyphenyl)pyrrolidin-2-one
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C20H17ClF2N4O2
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1
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| 1 |
EC50 > 10000 nM
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CP0424811
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2-ethyl-1-[(3R)-1-{[5-(trifluoromethoxy)-1H-indol-2-yl]carbonyl}pyrrolidin-3-yl]-1H-1,3-benzodiazole
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C23H21F3N4O2
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1
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| 1 |
EC50 = 12200 nM
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CP0453035
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1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-isopropylphenyl)urea
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C21H24N4O2
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1
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| 1 |
EC50 = 12300 nM
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CP0458640
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1-[(3R)-1-[(5-chloro-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl]-2-ethyl-1H-1,3-benzodiazole
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C22H21ClN4O
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1
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| 1 |
EC50 = 14100 nM
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CP0953132
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(3R,4R)-4-(2,6-difluoro-4-methoxyphenyl)-3-(5-methoxy-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
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C19H17F2N3O3
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1
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| 1 |
EC50 > 5000 nM
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