Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-phenylurea
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 PubChem ID
CID: 122583088
Canonical SMILES
COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1
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Compound Formula C18H17F2N3O3
Compound Structure
Protein Name
 Protein Info 
N-formyl peptide receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
N-formyl methionyl peptide receptor
Uniprot ID
P25090
Gene Name
FPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.41 nM
   TI
   LI
   LO
   TS
CL000018 HL-60
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 7.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 57 nM
   TI
   LI
   LO
   TS