Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT02333 , Cannabinoid receptor 2
Gene Name CNR2
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID Q9QZN9
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT02333
 
Compound ID Compound Name Compound Formula
CP0848879
8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2-methyl-9Hpurine Hydrochloride
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C18H22Cl2N6
 1
1
Ki = 4.3 nM
   TI
   LI
   LO
   TS
CP0691149
8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2,9-dimethyl-purine Hydrochloride
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C19H24Cl2N6
 1
1
Ki = 8.2 nM
   TI
   LI
   LO
   TS
CP0849004
8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-9-(2-methoxyethyl)-2-methyl-purine Hydrochloride
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C21H28Cl2N6O
 1
1
Ki = 10.7 nM
   TI
   LI
   LO
   TS
CP0238429
4-(4-ethylpiperazin-1-yl)-2-methyl-6-phenylthieno[2,3-d]pyrimidine
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C19H22N4S
 1
1
Ki = 16 nM
   TI
   LI
   LO
   TS
CP0877797
8-(2-Chlorophenyl)-6-[4-(2-fluoroethyl)piperazin-1-yl]-9-(2-methoxyethyl)-2-methyl-purine Hydrochloride
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C21H27Cl2FN6O
 1
1
Ki = 16 nM
   TI
   LI
   LO
   TS
CP0849001
8-(2-Chlorophenyl)-9-cyclopropyl-2-methyl-6-(4-methylpiperazin-1-yl)purine Hydrochloride
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C20H24Cl2N6
 1
1
Ki = 19.4 nM
   TI
   LI
   LO
   TS
CP0861732
8-(2-Cyclopropylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride
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C25H33ClN6O
 1
1
Ki = 21.8 nM
   TI
   LI
   LO
   TS
CP0848999
8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2-methyl-9-(tetrahydropyran-4-ylmethyl)purine Hydrochloride
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C24H32Cl2N6O
 1
1
Ki = 23.1 nM
   TI
   LI
   LO
   TS
CP0322795
8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3R)-oxolan-3-yl]purine
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C21H25ClN6O
 1
1
Ki = 24 nM
   TI
   LI
   LO
   TS
CP0881263
8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3R)-tetrahydrofuran-3-yl]purine Hydrochloride
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C21H26Cl2N6O
 1
1
Ki = 24 nM
   TI
   LI
   LO
   TS
CP0861735
8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride
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C22H28Cl2N6O
 1
1
Ki = 36.7 nM
   TI
   LI
   LO
   TS
CP0848880
1-[4-[8-(2-Chlorophenyl)-9-(2-methoxyethyl)-2-methylpurin-6-yl]piperazin-1-yl]ethanone Hydrochloride
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C21H26Cl2N6O2
 1
1
Ki = 39.7 nM
   TI
   LI
   LO
   TS
CP0848977
2-Methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-8-[2-(trifluoromethyl)phenyl]purine Hydrochloride
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C23H28ClF3N6O
 1
1
Ki = 40.4 nM
   TI
   LI
   LO
   TS
CP0442459
2-[8-(2-chlorophenyl)-9-(2-methoxyethyl)-2-methylpurin-6-yl]-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one;hydrochloride
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C22H26Cl2N6O2
 1
1
Ki = 41.2 nM
   TI
   LI
   LO
   TS
CP0861738
2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-purin-9-yl]ethanol Hydrochloride
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C19H24Cl2N6O
 1
1
Ki = 48.4 nM
   TI
   LI
   LO
   TS
CP0848983
8-(2-Ethylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride
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C24H33ClN6O
 1
1
Ki = 60 nM
   TI
   LI
   LO
   TS
CP0848877
8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3S)-tetrahydrofuran-3-yl]purine Hydrochloride
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C21H26Cl2N6O
 1
1
Ki = 83.7 nM
   TI
   LI
   LO
   TS
CP0409097
8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3S)-oxolan-3-yl]purine
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C21H25ClN6O
 1
1
Ki = 84 nM
   TI
   LI
   LO
   TS
CP0848972
2-Methyl-6-(4-methylpiperazin-1-yl)-8-(o-tolyl)-9-tetrahydropyran-4-yl-purine Hydrochloride
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C23H31ClN6O
 1
1
Ki = 87.1 nM
   TI
   LI
   LO
   TS
CP0861737
8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(2-methylsulfonylethyl)purine Hydrochloride
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C20H26Cl2N6O2S
 1
1
Ki = 87.4 nM
   TI
   LI
   LO
   TS
CP0848878
1-[2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9H-purin-9-yl]ethyl]pyrrolidin-2-one Hydrochloride
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C23H29Cl2N7O
 1
1
Ki = 459 nM
   TI
   LI
   LO
   TS