Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01871 , Proteinase-activated receptor 1
Gene Name F2R
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25116
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01871
 
Compound ID Compound Name Compound Formula
CP0869879
(E)-3-(2-Chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]-propenone
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C20H20ClFN2O
 1
1
Kd = 380.19 nM
   TI
   LI
   LO
   TS
CP0918477
(E)-2-(2-(3,4-dioxo-2-(4-(thiophen-3-ylmethyl)piperazin-1-yl)cyclobut-1-enyl)vinyl)benzonitrile
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C22H19N3O2S
 1
1
Kd = 389.05 nM
   TI
   LI
   LO
   TS
CP0930039
(Z)-3-(2-chlorophenyl)-1-(3-fluoro-4-(4-fluorophenylamino)piperidin-1-yl)prop-2-en-1-one
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C20H19ClF2N2O
 1
1
Kd = 389.05 nM
   TI
   LI
   LO
   TS
CP0930038
(E)-2-(2-(2-(4-(cyclohexylmethyl)piperazin-1-yl)-3,4-dioxocyclobut-1-enyl)vinyl)benzonitrile
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C24H27N3O2
 1
1
Kd = 426.58 nM
   TI
   LI
   LO
   TS
CP0845303
(Z)-2-(3-(3-fluoro-4-((4-fluorobenzyl)(pyridin-2-ylmethyl)amino)piperidin-1-yl)-3-oxoprop-1-enyl)benzonitrile
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C28H26F2N4O
 1
1
Kd = 588.84 nM
   TI
   LI
   LO
   TS
CP0845302
(E)-2-(3-(6-(cyclopentylamino)pyridin-3-yl)-3-oxoprop-1-enyl)benzonitrile
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C20H19N3O
 1
1
Kd = 933.25 nM
   TI
   LI
   LO
   TS