| Compound ID |
Compound Name |
Compound Formula |
|
CP0325271
|
(4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(pyrazin-2-yl)methanone
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|
C28H27N9O3
|
2
|
| 1 |
IC50 = 4900 nM
|
|
|
| 2 |
Ki = 147 nM
|
|
|
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CP0479945
|
4-phenyl-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
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|
C27H28N8
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki = 59000 nM
|
|
|
|
CP0502806
|
(4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(pyrazin-2-yl)methanone
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|
C28H28N8O
|
2
|
| 1 |
IC50 > 100000 nM
|
|
|
| 2 |
Ki = 8370 nM
|
|
|
|
CP0502810
|
4-(3-nitrophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
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|
C27H27N9O2
|
1
|
| 1 |
Ki = 2400 nM
|
|
|
|
CP0504539
|
3-(1-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propylamino)pyridazino[4,5-b]indolizin-4-yl)benzonitrile
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|
C28H27N9
|
1
|
| 1 |
Ki = 3350 nM
|
|
|
|
CP0514006
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyrazin-2-yl)methanone
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|
C26H29N9O3
|
1
|
| 1 |
Ki = 4440 nM
|
|
|
|
CP0504529
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyridin-2-yl)methanone
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|
C27H30N8O3
|
1
|
| 1 |
Ki = 11500 nM
|
|
|
|
CP0514005
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(thiazol-5-yl)methanone
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|
C25H28N8O3S
|
1
|
| 1 |
Ki = 12700 nM
|
|
|
|
CP0506240
|
4-(3-chlorophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
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|
C27H27ClN8
|
1
|
| 1 |
Ki = 14200 nM
|
|
|
|
CP0506241
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyridin-3-yl)methanone
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|
C27H30N8O3
|
1
|
| 1 |
Ki = 15300 nM
|
|
|
|
CP0479941
|
4-(3-bromophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
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|
C27H27BrN8
|
1
|
| 1 |
Ki = 17500 nM
|
|
|
|
CP0524331
|
(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(pyridin-2-yl)methanone
Show/Hide
|
C29H28FN7O
|
1
|
| 1 |
Ki = 18000 nM
|
|
|
|
CP0479947
|
(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(pyridin-3-yl)methanone
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|
C29H28FN7O
|
1
|
| 1 |
Ki = 19000 nM
|
|
|
|
CP0469057
|
(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(phenyl)methanone
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|
C30H29FN6O
|
1
|
| 1 |
Ki = 22200 nM
|
|
|
|
CP0901742
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(1,2,3-thiadiazol-4-yl)methanone
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|
C24H27N9O3S
|
1
|
| 1 |
Ki = 48600 nM
|
|
|
|
CP0504530
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyridazin-4-yl)methanone
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|
C26H29N9O3
|
1
|
| 1 |
Ki = 51200 nM
|
|
|
|
CP0508359
|
4-(3-methylphenyl)-N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]pyridazino[4,5-b]indolizin-1-amine
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|
C28H30N8
|
1
|
| 1 |
Ki = 54400 nM
|
|
|
|
CP0479942
|
cyclopentyl-[4-[3-[[4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-yl]amino]propyl]piperazin-1-yl]methanone
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|
C29H33FN6O
|
1
|
| 1 |
Ki = 61000 nM
|
|
|
|
CP0479946
|
(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(1-methyl-1H-pyrrol-2-yl)methanone
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|
C29H30FN7O
|
1
|
| 1 |
Ki = 65000 nM
|
|
|
|
CP0521450
|
(4-(3-(7-(3-chlorophenyl)-1,2-dimethyl-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyrimidin-2-yl)methanone
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|
C26H29ClN8O
|
1
|
| 1 |
Ki = 80900 nM
|
|
|
|
CP0504538
|
4-(3-fluorophenyl)-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
Show/Hide
|
C27H27FN8
|
1
|
| 1 |
Ki = 83000 nM
|
|
|
|
CP0469058
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyridin-4-yl)methanone
Show/Hide
|
C27H30N8O3
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0479944
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyrimidin-2-yl)methanone
Show/Hide
|
C26H29N9O3
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0504528
|
1-(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)propan-1-one
Show/Hide
|
C26H29FN6O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0507695
|
1-(4-(3-(4-(3-fluorophenyl)pyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)ethanone
Show/Hide
|
C25H27FN6O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0508357
|
(4-(3-(7-(3-fluorophenyl)-1,2-dimethyl-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyrimidin-2-yl)methanone
Show/Hide
|
C26H29FN8O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0518712
|
(4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(isoxazol-5-yl)methanone
Show/Hide
|
C25H28N8O4
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0524332
|
(4-(3-(1,2-dimethyl-7-phenyl-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyrimidin-2-yl)methanone
Show/Hide
|
C26H30N8O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
