Brief Information of the Compound and Protein
Compound Name
(4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamino)propyl)piperazin-1-yl)(pyrazin-2-yl)methanone
    Show/Hide
PubChem ID
CID: 46830337
SID: 99208099
Canonical SMILES
O=C(N1CCN(CCCNc2nnc(-c3ccccc3)c3c2cc2ccccn32)CC1)c1cnccn1
    Show/Hide
Compound Formula C28H28N8O
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4D
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4D
Uniprot ID
Q08499
Gene Name
PDE4D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
2
Ki = 8370 nM
   TI
   LI
   LO
   TS