Brief Information of the Compound and Protein
Compound Name
4-phenyl-N-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propyl)pyridazino[4,5-b]indolizin-1-amine
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PubChem ID
CID: 46884033
Canonical SMILES
C(CNc1nnc(-c2ccccc2)c2c1cc1ccccn21)CN1CCN(CC1)c1ncccn1
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Compound Formula C27H28N8
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4D
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4D
Uniprot ID
Q08499
Gene Name
PDE4D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
2
Ki = 59000 nM
   TI
   LI
   LO
   TS