| Compound ID |
Compound Name |
Compound Formula |
|
CP0216238
|
(4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
Show/Hide
|
C30H39N5O7S2
|
2
|
| 1 |
EC50 = 1.43 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
|
CP0402123
|
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
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|
C30H36N2O3
|
2
|
| 1 |
EC50 = 21.14 nM
|
|
|
| 2 |
Ki = 33.3 nM
|
|
|
|
CP0390006
|
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-(4-phenylphenyl)methanone
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|
C38H41NO4
|
1
|
| 1 |
EC50 = 31.2 nM
|
|
|
|
CP0402128
|
N-benzyl-4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
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|
C37H42N2O3
|
2
|
| 1 |
EC50 = 78.89 nM
|
|
|
| 2 |
Ki = 626.3 nM
|
|
|
|
CP0390907
|
[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]methanol
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|
C26H35NO4
|
1
|
| 1 |
EC50 = 90.8 nM
|
|
|
|
CP0528414
|
3-[(dimethylamino)methyl]-4-hydroxy-4-(3-hydroxyphenyl)-N-phenylpiperidine-1-carboxamide;hydrochloride
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|
C21H28ClN3O3
|
2
|
| 1 |
EC50 = 112.2 nM
|
|
|
| 2 |
Ki = 103.6 nM
|
|
|
|
CP0402129
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-2-phenylacetamide
Show/Hide
|
C38H42N2O4
|
2
|
| 1 |
EC50 = 132.4 nM
|
|
|
| 2 |
Ki = 131.8 nM
|
|
|
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CP0396636
|
(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene-16-carbaldehyde
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|
C26H33NO4
|
1
|
| 1 |
EC50 = 143.9 nM
|
|
|
|
CP0390005
|
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-(4-methoxyphenyl)methanone
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|
C33H39NO5
|
1
|
| 1 |
EC50 = 593.8 nM
|
|
|
|
CP0396635
|
[(1R,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,18-tetraen-16-yl]-phenylmethanone
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|
C31H33NO4
|
1
|
| 1 |
EC50 = 678.2 nM
|
|
|
|
CP0445821
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]benzamide
Show/Hide
|
C37H40N2O4
|
2
|
| 1 |
EC50 = 794.1 nM
|
|
|
| 2 |
Ki = 133.7 nM
|
|
|
|
CP0389202
|
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-[4-(trifluoromethyl)phenyl]methanone
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|
C33H36F3NO4
|
1
|
| 1 |
EC50 = 1759 nM
|
|
|
|
CP0389201
|
[(1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-phenylmethanone
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|
C32H37NO4
|
1
|
| 1 |
EC50 = 9988 nM
|
|
|
|
CP0384887
|
(2R)-2-[[(2R)-2-[[2-[[(1R,2S)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclohexanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
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|
C33H45N5O8
|
1
|
| 1 |
IC50 = 0.01 nM
|
|
|
|
CP0375306
|
(2R)-2-[[(2R)-2-[[2-[[(1R,2S)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclopentanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Show/Hide
|
C32H43N5O8
|
2
|
| 1 |
IC50 = 0.01 nM
|
|
|
| 2 |
IC50 = 0.04 nM
|
|
|
|
CP0402489
|
(R)-2-[(R)-2-(2-{(R)-2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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|
C30H41N5O8
|
2
|
| 1 |
IC50 = 0.071 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0076658
|
(R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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|
C28H37N5O7
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0038418
|
13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid
Show/Hide
|
C30H39N5O7S2
|
2
|
| 1 |
IC50 = 0.63 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0455130
|
(2R)-2-[[(2R)-2-[[2-[[(1R,2R)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclohexanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Show/Hide
|
C33H45N5O8
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
|
CP0399819
|
(2R)-2-[[(2R)-2-[[2-[[(1S,2R)-1-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-2-hydroxycyclopentanecarbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
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|
C32H43N5O8
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0375261
|
(R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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|
C30H41N5O7
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
|
CP0846695
|
2-[2-(2-{2-[2-Dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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|
C42H49N5O7
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0916467
|
2-[2-(2-{2-[2-Dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(4-isothiocyanato-phenyl)-propionylamino]-4-methyl-pentanoic acid
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|
C43H48N6O7S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0866945
|
2-[3-(4-Amino-phenyl)-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid
Show/Hide
|
C42H50N6O7
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0437453
|
(R)-2-[(R)-2-(2-{(S)-2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-2-methyl-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
Show/Hide
|
C30H41N5O8
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 = 5000 nM
|
|
|
|
CP0448264
|
2-[3-[4-(2-Bromo-acetylamino)-phenyl]-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid
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|
C44H51BrN6O8
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0845390
|
2-[3-[4-(2-Bromo-acetylamino)-phenyl]-2-(2-{2-[2-diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-propionylamino]-4-methyl-pentanoic acid
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|
C38H51BrN6O8
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0053097
|
2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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|
C38H53N5O7
|
1
|
| 1 |
IC50 = 18900 nM
|
|
|
|
CP0895837
|
2-[3-[4-(Chloromethyl-amino)-phenyl]-2-(2-{2-[2-dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-propionylamino]-4-methyl-pentanoic acid
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|
C43H51ClN6O7
|
1
|
| 1 |
IC50 = 19000 nM
|
|
|
|
CP0866750
|
2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-3-(4-isothiocyanato-phenyl)-propionylamino]-4-methyl-pentanoic acid
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|
C37H48N6O7S
|
1
|
| 1 |
IC50 = 33400 nM
|
|
|
|
CP0955372
|
2-[3-(4-Amino-phenyl)-2-(2-{2-[2-diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-propionylamino)-propionylamino]-4-methyl-pentanoic acid
Show/Hide
|
C37H52N6O7
|
1
|
| 1 |
IC50 = 87700 nM
|
|
|
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CP0402124
|
ethyl 3-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]anilino]propanoate
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|
C35H44N2O5
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
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CP0549043
|
1-[4-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]piperazin-1-yl]ethanone
Show/Hide
|
C36H45N3O4
|
1
|
| 1 |
Ki = 22 nM
|
|
|
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CP0450717
|
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-ethylaniline
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|
C32H40N2O3
|
1
|
| 1 |
Ki = 42.8 nM
|
|
|
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CP0402125
|
[4-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C41H47N3O4
|
1
|
| 1 |
Ki = 48.23 nM
|
|
|
|
CP0466725
|
2-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]anilino]acetamide
Show/Hide
|
C32H39N3O4
|
1
|
| 1 |
Ki = 57.3 nM
|
|
|
|
CP0000305
|
(-)-(etorphine)
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|
C17H19NO3
|
1
|
| 1 |
Ki = 76.9 nM
|
|
|
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CP0402126
|
N-(cyclopropylmethyl)-4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]aniline
Show/Hide
|
C34H42N2O3
|
1
|
| 1 |
Ki = 87.2 nM
|
|
|
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CP0445819
|
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-methylaniline
Show/Hide
|
C31H38N2O3
|
1
|
| 1 |
Ki = 94.7 nM
|
|
|
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CP0519314
|
4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]-N-propylaniline
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|
C33H42N2O3
|
1
|
| 1 |
Ki = 114.8 nM
|
|
|
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CP0445820
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]formamide
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|
C31H36N2O4
|
1
|
| 1 |
Ki = 132.5 nM
|
|
|
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CP0532486
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-N',N'-dimethylethane-1,2-diamine
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|
C34H45N3O3
|
1
|
| 1 |
Ki = 137.5 nM
|
|
|
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CP0479103
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[4-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
Show/Hide
|
C38H49N3O3
|
1
|
| 1 |
Ki = 179.1 nM
|
|
|
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CP0382612
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]acetamide
Show/Hide
|
C32H38N2O4
|
1
|
| 1 |
Ki = 215.9 nM
|
|
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CP0533460
|
N-(3-chlorophenyl)-3-[(dimethylamino)methyl]-4-hydroxy-4-phenylpiperidine-1-carboxamide;hydrochloride
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|
C21H27Cl2N3O2
|
1
|
| 1 |
Ki = 537 nM
|
|
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CP0559030
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-piperazin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
Show/Hide
|
C34H43N3O3
|
1
|
| 1 |
Ki = 820.7 nM
|
|
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CP0487716
|
3-[(dimethylamino)methyl]-4-hydroxy-N,4-diphenylpiperidine-1-carboxamide;hydrochloride
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|
C21H28ClN3O2
|
1
|
| 1 |
Ki = 849.4 nM
|
|
|
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CP0519315
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-pyrrolidin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
Show/Hide
|
C34H42N2O3
|
1
|
| 1 |
Ki = 962.2 nM
|
|
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CP0567441
|
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-(4-piperidin-1-ylphenyl)-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
Show/Hide
|
C35H44N2O3
|
1
|
| 1 |
Ki = 1030 nM
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|
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CP0445818
|
N-[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]-N',N'-dimethylpropane-1,3-diamine
Show/Hide
|
C35H47N3O3
|
1
|
| 1 |
Ki = 1201 nM
|
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CP0085967
|
7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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|
C27H29NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0122977
|
21-nitro-7alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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|
C27H28N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0181621
|
8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
Show/Hide
|
C27H29NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0214836
|
21-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
Show/Hide
|
C27H28N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0268749
|
22-nitro-8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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|
C27H28N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0281227
|
22-nitro-7apha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine
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|
C27H28N2O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0216880
|
Ac-Phe-Phe-Phe-Arg-Leu-Arg-Arg-D-Ala-Arg-Pro-Lys-NH2
Show/Hide
|
C73H115N25O12
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
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CP0450716
|
4-[[4-[(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-16-yl]phenyl]diazenyl]phenol
Show/Hide
|
C36H39N3O4
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
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CP0571312
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(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-11,15-dimethoxy-16-[4-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]phenyl]-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-triene
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C41H49N3O5S
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1
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| 1 |
Ki > 5000 nM
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