Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01028 , Ephrin type-B receptor 4
 Protein Info 
Gene Name EPHB4
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P54760
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT01028
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0078397
 Compound Info 
6-butyl-7-[5-(1H-indazol-4-yl)-2-methylphenyl]-4-methylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C26H25N7O2
  2
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 133 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0128740
 Compound Info 
6-butyl-4-methyl-7-(2-methylphenyl)purino[7,8-a]imidazole-1,3-dione
   Show/Hide
C19H21N5O2
  2
1
IC50 = 56 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 82 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0128742
 Compound Info 
6-butyl-7-(4-fluoro-2-methylphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C19H20FN5O2
  2
1
IC50 = 91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 139 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0449284
 Compound Info 
4-methyl-7-(2-methylphenyl)-6-pentylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C20H23N5O2
  1
1
IC50 = 177 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440945
 Compound Info 
6-butyl-7-(2-chlorophenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C18H18ClN5O2
  1
1
IC50 = 182 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0392382
 Compound Info 
7-(2-chlorophenyl)-6-(2-methoxyphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C21H16ClN5O3
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0140813
 Compound Info 
6-butyl-4-methyl-7-phenylpurino[7,8-a]imidazole-1,3-dione
   Show/Hide
C18H19N5O2
  2
1
IC50 = 538 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0440153
 Compound Info 
6-hexyl-4-methyl-7-(2-methylphenyl)purino[7,8-a]imidazole-1,3-dione
   Show/Hide
C21H25N5O2
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0302715
 Compound Info 
8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1,2-f]purine-2,4(3H,8H)-dione
   Show/Hide
C21H17N5O3
  2
1
IC50 = 3300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 4350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS