Brief Information of the Compound and Protein
Compound Name
8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1,2-f]purine-2,4(3H,8H)-dione
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PubChem ID
CID: 4886490
Canonical SMILES
COc1ccccc1-n1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1ccccc1
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Compound Formula C21H17N5O3
Compound Structure
Protein Name
Ephrin type-B receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Eph family
Uniprot ID
P54760
Gene Name
EPHB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
2
IC50 = 4350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3300 nM
2 IC50 = 4350 nM