| Compound ID |
Compound Name |
Compound Formula |
|
CP0235875
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C69H108N22O16S
|
14
|
| 1 |
EC50 = 0.0122 nM
|
|
|
| 2 |
EC50 = 0.047 nM
|
|
|
| 3 |
EC50 = 0.05 nM
|
|
|
| 4 |
EC50 = 0.84 nM
|
|
|
| 5 |
EC50 = 1.1 nM
|
|
|
| 6 |
EC50 = 1.4 nM
|
|
|
| 7 |
EC50 = 5.9 nM
|
|
|
| 8 |
EC50 = 24 nM
|
|
|
| 9 |
EC50 = 26 nM
|
|
|
| 10 |
EC50 = 29 nM
|
|
|
| 11 |
EC50 = 60 nM
|
|
|
| 12 |
IC50 = 1.2 nM
|
|
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| 13 |
Ki = 0.7 nM
|
|
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| 14 |
Ki = 1 nM
|
|
|
|
CP0543003
|
CHEMBL5192130
Show/Hide
|
C27H25F2N5O5
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0551963
|
5-[3-(2,4-difluorophenyl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-6-hydroxypyrimidin-4-one
Show/Hide
|
C26H27F2N3O6
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0567804
|
5-[3-(2,4-difluorophenyl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-6-hydroxy-2-(1-methylpyrazol-3-yl)pyrimidin-4-one
Show/Hide
|
C27H25F2N5O5
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0575415
|
3-(2,6-dimethoxyphenyl)-5-[(3R)-3-(2-fluorophenyl)pyrrolidine-1-carbonyl]-6-hydroxy-2-(1-methylpyrazol-3-yl)pyrimidin-4-one
Show/Hide
|
C27H26FN5O5
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0575416
|
CHEMBL5202635
Show/Hide
|
C28H28F2N6O3
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0579354
|
CHEMBL5193130
Show/Hide
|
C29H29F2N5O3
|
1
|
| 1 |
EC50 = 0.02 nM
|
|
|
|
CP0533812
|
3-{5-[(5- chloropyridin-2- yl)methyl]-1,3,4- oxadiazol-2-yl}-5- (2,6- dimethoxyphenyl)- 6-(ethoxymethyl) pyridine-2,4-diol
Show/Hide
|
C24H23ClN4O6
|
1
|
| 1 |
EC50 = 0.023 nM
|
|
|
|
CP0545340
|
3-(2,6-diethylphenyl)-5-[3-(3-fluoropyridin-2-yl)pyrrolidine-1-carbonyl]-6-hydroxy-2-(1-methylpyrazol-3-yl)pyrimidin-4-one
Show/Hide
|
C28H29FN6O3
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
|
CP0576414
|
5-[3-(2,4-difluorophenyl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-6-hydroxy-2-(2-methyl-1,3-thiazol-4-yl)pyrimidin-4-one
Show/Hide
|
C27H24F2N4O5S
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
|
CP0906816
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-benzoylphenyl)propanoic acid
Show/Hide
|
C77H114N22O17
|
4
|
| 1 |
EC50 = 0.04 nM
|
|
|
| 2 |
EC50 = 0.91 nM
|
|
|
| 3 |
IC50 = 0.48 nM
|
|
|
| 4 |
Ki = 0.38 nM
|
|
|
|
CP0577327
|
CHEMBL5197398
Show/Hide
|
C29H30FN5O3
|
1
|
| 1 |
EC50 = 0.04 nM
|
|
|
|
CP0153773
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C69H111N23O16S
|
3
|
| 1 |
EC50 = 0.05 nM
|
|
|
| 2 |
EC50 = 40 nM
|
|
|
| 3 |
Ki = 0.7 nM
|
|
|
|
CP0567803
|
CHEMBL5170657
Show/Hide
|
C28H28ClFN6O3
|
1
|
| 1 |
EC50 = 0.06 nM
|
|
|
|
CP0466444
|
2-[2-chloro-6-(6-methoxy-1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C32H28ClN3O4
|
1
|
| 1 |
EC50 = 0.062 nM
|
|
|
|
CP0886417
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-2-methyl-3-phenylpropanoic acid
Show/Hide
|
C71H112N22O16
|
4
|
| 1 |
EC50 = 0.07 nM
|
|
|
| 2 |
EC50 = 2.7 nM
|
|
|
| 3 |
IC50 = 0.43 nM
|
|
|
| 4 |
Ki = 0.34 nM
|
|
|
|
CP0903194
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-guanidino-2-[[(2S)-1-[(2S)-5-guanidino-2-[[(2S)-5-oxotetrahydrofuran-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methyl-pentanoyl]amino]-3-hydroxy-propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanyl-butanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoic acid
Show/Hide
|
C69H107N21O17S
|
1
|
| 1 |
EC50 = 0.07 nM
|
|
|
|
CP0551962
|
3-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-5-[(3R)-3-(2-fluorophenyl)pyrrolidine-1-carbonyl]-6-hydroxypyrimidin-4-one
Show/Hide
|
C26H28FN3O6
|
1
|
| 1 |
EC50 = 0.07 nM
|
|
|
|
CP0402068
|
2-[5-chloro-2-(6-methoxy-1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C32H28ClN3O4
|
1
|
| 1 |
EC50 = 0.083 nM
|
|
|
|
CP0575163
|
3-[3-(3,5-difluoropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-6-(3-methylphenyl)-1H-pyridin-2-one
Show/Hide
|
C30H28F2N4O3
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0514614
|
3-{5-[(4- chlorophenyl) methyl]-1,3,4- oxadiazol- 2-yl}-5-(2,6- dimethoxyphenyl)- 6-(ethoxymethyl) pyridine-2,4-diol
Show/Hide
|
C25H24ClN3O6
|
1
|
| 1 |
EC50 = 0.12 nM
|
|
|
|
CP0918460
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-p-tolylpropanoic acid
Show/Hide
|
C71H112N22O16
|
4
|
| 1 |
EC50 = 0.17 nM
|
|
|
| 2 |
EC50 = 1.4 nM
|
|
|
| 3 |
IC50 = 0.25 nM
|
|
|
| 4 |
Ki = 0.2 nM
|
|
|
|
CP0549142
|
3-{5-[(6- chloropyridin-3- yl)methyl]-1,3,4- oxadiazol-2-yl}-5- (2,6- dimethoxyphenyl)- 6-(ethoxymethyl) pyridine-2,4-diol
Show/Hide
|
C24H23ClN4O6
|
1
|
| 1 |
EC50 = 0.17 nM
|
|
|
|
CP0402144
|
2-[2-(1H-benzimidazol-2-yl)-6-methylphenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C32H29N3O3
|
1
|
| 1 |
EC50 = 0.18 nM
|
|
|
|
CP0471798
|
2-[5-chloro-2-[(3-fluoro-4-methoxyphenyl)carbamoyl]phenyl]-5-[[(1S)-2-methoxy-1-phenylethyl]carbamoyl]benzoic acid
Show/Hide
|
C31H26ClFN2O6
|
1
|
| 1 |
EC50 = 0.19 nM
|
|
|
|
CP0578549
|
3-(2,6-dimethoxyphenyl)-2-(4-fluorophenyl)-5-[(3R)-3-(2-fluorophenyl)pyrrolidine-1-carbonyl]-6-hydroxypyrimidin-4-one
Show/Hide
|
C29H25F2N3O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0579850
|
5-[3-(2,4-difluorophenyl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-6-hydroxy-2-(6-methylpyridin-3-yl)pyrimidin-4-one
Show/Hide
|
C29H26F2N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0883106
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-methoxyphenyl)propanoic acid
Show/Hide
|
C71H112N22O17
|
4
|
| 1 |
EC50 = 0.23 nM
|
|
|
| 2 |
EC50 = 1.3 nM
|
|
|
| 3 |
IC50 = 0.6 nM
|
|
|
| 4 |
Ki = 0.48 nM
|
|
|
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CP0858328
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-4-phenylbutanoic acid
Show/Hide
|
C71H112N22O16
|
4
|
| 1 |
EC50 = 0.24 nM
|
|
|
| 2 |
EC50 = 1.4 nM
|
|
|
| 3 |
IC50 = 6.7 nM
|
|
|
| 4 |
Ki = 5.4 nM
|
|
|
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CP0551841
|
3-{5-[(4- chlorophenyl) methyl]- 1,3,4-oxadiazol- 2-yl}-6- cyclopentyl-5-(2,6- dimethoxyphenyl) pyridine-2,4-diol
Show/Hide
|
C27H26ClN3O5
|
1
|
| 1 |
EC50 = 0.24 nM
|
|
|
|
CP0540348
|
6-butyl-3-[3-(3,5-difluoropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-1H-pyridin-2-one
Show/Hide
|
C27H30F2N4O3
|
1
|
| 1 |
EC50 = 0.24 nM
|
|
|
|
CP0579821
|
6-butyl-3-[3-(5-chloro-3-fluoropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-1H-pyridin-2-one
Show/Hide
|
C27H30ClFN4O3
|
1
|
| 1 |
EC50 = 0.24 nM
|
|
|
|
CP0551929
|
6-butyl-3-[3-(5-chloropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-1H-pyridin-2-one
Show/Hide
|
C27H31ClN4O3
|
1
|
| 1 |
EC50 = 0.28 nM
|
|
|
|
CP0578964
|
3-[3-(3,5-difluoropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-6-(1-methylpyrazol-3-yl)-1H-pyridin-2-one
Show/Hide
|
C27H26F2N6O3
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0445871
|
2-[5-chloro-2-(6-chloro-1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C31H25Cl2N3O3
|
1
|
| 1 |
EC50 = 0.31 nM
|
|
|
|
CP0478814
|
2-[5-chloro-2-[(3-fluoro-4-methoxyphenyl)carbamoyl]phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C32H28ClFN2O5
|
1
|
| 1 |
EC50 = 0.33 nM
|
|
|
|
CP0883107
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoic acid
Show/Hide
|
C77H116N22O17
|
7
|
| 1 |
EC50 = 0.35 nM
|
|
|
| 2 |
EC50 = 1.1 nM
|
|
|
| 3 |
EC50 = 1.4 nM
|
|
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| 4 |
EC50 = 7.4 nM
|
|
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| 5 |
EC50 = 13 nM
|
|
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| 6 |
IC50 = 0.02 nM
|
|
|
| 7 |
Ki = 0.016 nM
|
|
|
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CP0471112
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-aminopent-4-enoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]pent-4-enoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C69H108N22O15
|
3
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
EC50 = 35 nM
|
|
|
| 3 |
Ki = 2.5 nM
|
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CP0551840
|
6-butyl-3-{5-[(4- chlorophenyl) methyl]-1,3,4- oxadiazol- 2-yl}-5-(2,6- dimethoxyphenyl) pyridine-2,4-diol
Show/Hide
|
C26H26ClN3O5
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0555754
|
3-(2,6-dimethoxyphenyl)-2-(ethoxymethyl)-6-hydroxy-5-[(3R)-3-phenylpyrrolidine-1-carbonyl]pyrimidin-4-one
Show/Hide
|
C26H29N3O6
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0577570
|
CHEMBL5185709
Show/Hide
|
C27H29N3O6
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0902104
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(pyridin-4-yl)propanoic acid
Show/Hide
|
C69H109N23O16
|
4
|
| 1 |
EC50 = 0.45 nM
|
|
|
| 2 |
EC50 = 0.73 nM
|
|
|
| 3 |
IC50 = 1.3 nM
|
|
|
| 4 |
Ki = 1 nM
|
|
|
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CP0402042
|
2-[2-(1H-benzimidazol-2-yl)-6-fluorophenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C31H26FN3O3
|
1
|
| 1 |
EC50 = 0.51 nM
|
|
|
|
CP0875978
|
(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
|
C70H110N22O16
|
5
|
| 1 |
EC50 = 0.53 nM
|
|
|
| 2 |
EC50 = 4.5 nM
|
|
|
| 3 |
IC50 = 2.6 nM
|
|
|
| 4 |
Ki = 0.8 nM
|
|
|
| 5 |
Ki = 2.1 nM
|
|
|
|
CP0445870
|
2-[5-chloro-2-(6-methyl-1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
|
C32H28ClN3O3
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0545339
|
CHEMBL5206677
Show/Hide
|
C28H31N3O6
|
1
|
| 1 |
EC50 = 0.6 nM
|
|
|
|
CP0954511
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-5-phenylpent-4-enoic acid
Show/Hide
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C72H112N22O16
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4
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| 1 |
EC50 = 0.63 nM
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| 2 |
EC50 = 3.4 nM
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| 3 |
IC50 = 1.5 nM
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| 4 |
Ki = 1.2 nM
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CP0432702
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(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]pent-4-enoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]pent-4-enoyl]amino]-3-phenylpropanoic acid
Show/Hide
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C69H105N21O16
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3
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| 1 |
EC50 = 0.8 nM
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| 2 |
EC50 = 58 nM
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| 3 |
Ki = 2.3 nM
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CP0532920
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(2R)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-1-ylpropanoic acid
Show/Hide
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C49H73N13O11
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4
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| 1 |
EC50 = 0.8 nM
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| 2 |
EC50 = 31 nM
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| 3 |
EC50 > 10000 nM
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| 4 |
Ki = 0.6 nM
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CP0943742
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[Pyr1]-Apelin-13
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C69H110N22O15S
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7
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| 1 |
EC50 = 0.8 nM
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| 2 |
EC50 = 37 nM
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| 3 |
EC50 = 49 nM
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| 4 |
IC50 = 2.2 nM
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| 5 |
IC50 = 5.4 nM
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| 6 |
IC50 = 17 nM
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| 7 |
Ki = 0.6 nM
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CP0858325
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-2-methyl-3-phenylpropanoic acid
Show/Hide
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C71H112N22O16
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4
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| 1 |
EC50 = 0.86 nM
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| 2 |
EC50 = 2.8 nM
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| 3 |
IC50 = 0.86 nM
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| 4 |
Ki = 0.69 nM
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CP0546376
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3-[5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-yl]-5-(2,6-dimethoxyphenyl)-4-hydroxy-6-(2-methoxyethyl)-1H-pyridin-2-one
Show/Hide
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C25H24ClN3O6
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1
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| 1 |
EC50 = 0.94 nM
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CP0432701
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]pent-4-enoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]pent-4-enoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C68H106N20O16
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3
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| 1 |
EC50 = 1 nM
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| 2 |
EC50 = 42 nM
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| 3 |
Ki = 0.3 nM
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CP0959379
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(R)-6-butyl-5-(2,6-dimethoxyphenyl)-4-hydroxy-3-(3-phenylpyrrolidine-1-carbonyl)pyridin-2(1H)-one
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C28H32N2O5
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1
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| 1 |
EC50 = 1 nM
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CP0848655
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1-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-2,3-dihydro-1H-indene-1-carboxylic acid
Show/Hide
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C71H110N22O16
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4
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| 1 |
EC50 = 1.1 nM
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| 2 |
EC50 = 1.4 nM
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| 3 |
IC50 = 1.7 nM
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| 4 |
Ki = 1.4 nM
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CP0953641
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-3-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C57H89N15O12
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3
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| 1 |
EC50 = 1.1 nM
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| 2 |
EC50 = 88 nM
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| 3 |
Ki = 1.1 nM
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CP0944660
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S)-3-((1H-imidazol-5-yl)methyl)-1-(1-((S)-1-((S)-2-aminohexanoyl)pyrrolidine-2-carboxamido)cyclopentyl)-9-(3-guanidinopropyl)-6-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H85N15O12
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3
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| 1 |
EC50 = 1.2 nM
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| 2 |
EC50 = 79 nM
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| 3 |
Ki = 2.4 nM
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CP0542602
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(3E,6S,9S,12S,15S,18S)-6-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-9-[3-(diaminomethylideneamino)propyl]-15-(hydroxymethyl)-12-(2-methylpropyl)-7,10,13,16-tetraoxo-1,8,11,14,17,22-hexazabicyclo[18.3.0]tricosa-3,20,22-triene-18-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C71H110N22O16
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4
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| 1 |
EC50 = 1.2 nM
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| 2 |
EC50 = 6.6 nM
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| 3 |
EC50 = 33 nM
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| 4 |
Ki = 0.9 nM
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CP0865444
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(benzo[b]thiophen-3-yl)propanoic acid
Show/Hide
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C72H110N22O16S
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3
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| 1 |
EC50 = 1.3 nM
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| 2 |
IC50 = 2.8 nM
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| 3 |
Ki = 2.2 nM
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CP0902105
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-4-methylpentanoic acid
Show/Hide
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C67H112N22O16
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4
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| 1 |
EC50 = 1.3 nM
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| 2 |
EC50 = 2.9 nM
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| 3 |
IC50 = 7.9 nM
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| 4 |
Ki = 6.3 nM
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CP0558282
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(3S,6S,12S,17Z,20S,23S)-12-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-butyl-15-(2-nitrophenyl)sulfonyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
Show/Hide
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C75H116N24O20S
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4
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| 1 |
EC50 = 1.3 nM
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| 2 |
EC50 = 45 nM
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| 3 |
EC50 = 57 nM
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| 4 |
Ki = 0.15 nM
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CP0533816
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2-[2-(1H-benzimidazol-2-yl)-5-chlorophenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C31H26ClN3O3
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1
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| 1 |
EC50 = 1.4 nM
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CP0532918
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-(diaminomethylideneamino)-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C57H91N17O13
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4
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| 1 |
EC50 = 1.4 nM
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| 2 |
EC50 = 33 nM
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| 3 |
EC50 = 110 nM
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| 4 |
Ki = 1.7 nM
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CP0491469
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2-[2-(1H-benzimidazol-2-yl)-5-methylphenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C32H29N3O3
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1
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| 1 |
EC50 = 1.5 nM
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CP0454621
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(3S,6S,12S,17Z,20R,23S)-12-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-butyl-15-(2-nitrophenyl)sulfonyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
Show/Hide
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C75H116N24O20S
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3
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| 1 |
EC50 = 1.7 nM
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| 2 |
EC50 = 63 nM
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| 3 |
Ki = 0.1 nM
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CP0579851
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5-[3-(2,4-difluorophenyl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-6-hydroxy-2-(5-methylpyridin-2-yl)pyrimidin-4-one
Show/Hide
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C29H26F2N4O5
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1
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| 1 |
EC50 = 1.8 nM
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CP0177110
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C69H108N22O16S
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4
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| 1 |
EC50 = 1.9 nM
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| 2 |
EC50 = 16 nM
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| 3 |
EC50 = 68 nM
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| 4 |
Ki = 0.37 nM
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CP0546227
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2-cyclopentyl-3-(2,6-dimethoxyphenyl)-6-hydroxy-5-[(3R)-3-phenylpyrrolidine-1-carbonyl]pyrimidin-4-one
Show/Hide
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C28H31N3O5
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1
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| 1 |
EC50 = 1.9 nM
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CP0577325
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3-(2,6-dimethoxyphenyl)-6-hydroxy-5-[(3R)-3-phenylpyrrolidine-1-carbonyl]-2-(4,4,4-trifluorobutyl)pyrimidin-4-one
Show/Hide
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C27H28F3N3O5
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1
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| 1 |
EC50 = 1.9 nM
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CP0865443
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(pyridin-3-yl)propanoic acid
Show/Hide
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C69H109N23O16
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4
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| 1 |
EC50 = 2 nM
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| 2 |
EC50 = 2.3 nM
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| 3 |
IC50 = 1.6 nM
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| 4 |
Ki = 1.3 nM
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CP0432705
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]pent-4-enoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]pent-4-enoic acid
Show/Hide
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C69H112N22O16
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3
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| 1 |
EC50 = 2 nM
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| 2 |
EC50 = 145 nM
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| 3 |
Ki = 2.1 nM
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CP0413034
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]-prop-2-enylamino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]pent-4-enoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C72H109N21O16
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3
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| 1 |
EC50 = 2.1 nM
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| 2 |
EC50 = 91 nM
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| 3 |
Ki = 2.7 nM
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CP0955253
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-phenylpropanoic acid
Show/Hide
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C60H89N15O12
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3
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| 1 |
EC50 = 2.3 nM
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| 2 |
EC50 = 53 nM
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| 3 |
Ki = 4 nM
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CP0953643
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-3-tert-butyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H87N15O12
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3
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| 1 |
EC50 = 2.4 nM
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| 2 |
EC50 = 401 nM
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| 3 |
Ki = 21 nM
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CP0495403
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(2R)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-2-ylpropanoic acid
Show/Hide
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C49H73N13O11
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4
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| 1 |
EC50 = 2.4 nM
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| 2 |
EC50 = 5 nM
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| 3 |
EC50 = 232 nM
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| 4 |
Ki = 5.7 nM
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CP0858327
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(2S,3S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid
Show/Hide
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C67H112N22O16
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4
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| 1 |
EC50 = 2.5 nM
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| 2 |
EC50 = 3.1 nM
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| 3 |
IC50 = 11.4 nM
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| 4 |
Ki = 9.1 nM
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CP0551839
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6-butyl-3-{5-[(3- chlorophenyl) methyl]-1,3,4- oxadiazol- 2-yl}-5-(2,6- dimethoxyphenyl) pyridine-2,4-diol
Show/Hide
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C26H26ClN3O5
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1
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| 1 |
EC50 = 2.6 nM
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CP0495404
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16E,19S)-19-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-14-methyl-5-(2-methylpropyl)-3,6,9,20-tetraoxo-1,4,7,10,14-pentazacycloicos-16-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C70H113N21O16
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4
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| 1 |
EC50 = 2.6 nM
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| 2 |
EC50 = 41 nM
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| 3 |
EC50 = 157 nM
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| 4 |
Ki = 1.7 nM
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CP0946320
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-15-(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-9,21,29-trimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C82H133N17O17
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1
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| 1 |
EC50 = 2.7 nM
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CP0858326
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-methylbutanoic acid
Show/Hide
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C66H110N22O16
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4
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| 1 |
EC50 = 2.7 nM
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| 2 |
EC50 = 4.7 nM
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| 3 |
IC50 = 18.2 nM
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| 4 |
Ki = 14.6 nM
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CP0865445
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-2-phenylacetic acid
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C69H108N22O16
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4
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| 1 |
EC50 = 2.7 nM
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| 2 |
EC50 = 4.2 nM
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| 3 |
IC50 = 14.3 nM
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| 4 |
Ki = 11.4 nM
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CP0445866
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2-[5-chloro-2-[(3-fluoro-4-methoxyphenyl)carbamoyl]phenyl]-5-[[(1R)-2-methoxy-1-phenylethyl]carbamoyl]benzoic acid
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C31H26ClFN2O6
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1
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| 1 |
EC50 = 2.7 nM
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CP0953645
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-3-(cyclohexylmethyl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C59H91N15O12
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3
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| 1 |
EC50 = 2.8 nM
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| 2 |
EC50 = 120 nM
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| 3 |
Ki = 4 nM
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CP0858324
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(pyridin-2-yl)propanoic acid
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C69H109N23O16
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4
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| 1 |
EC50 = 3 nM
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| 2 |
EC50 = 3.6 nM
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| 3 |
IC50 = 6.1 nM
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| 4 |
Ki = 4.9 nM
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CP0495405
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16S)-16-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadecane-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C67H108N20O16
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4
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| 1 |
EC50 = 3.3 nM
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| 2 |
EC50 = 63 nM
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| 3 |
EC50 = 199 nM
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| 4 |
Ki = 4.3 nM
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CP0528064
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16E,19S)-19-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-14-(2-nitrophenyl)sulfonyl-3,6,9,20-tetraoxo-1,4,7,10,14-pentazacycloicos-16-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C75H114N22O20S
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4
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| 1 |
EC50 = 3.6 nM
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| 2 |
EC50 = 19 nM
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| 3 |
EC50 = 99 nM
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| 4 |
Ki = 0.2 nM
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CP0413033
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C67H106N20O16
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4
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| 1 |
EC50 = 3.7 nM
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| 2 |
EC50 = 22 nM
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| 3 |
EC50 = 126 nM
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| 4 |
Ki = 3 nM
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CP0871209
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(naphthalen-2-yl)propanoic acid
Show/Hide
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C64H91N15O12
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3
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| 1 |
EC50 = 3.8 nM
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| 2 |
EC50 = 107 nM
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| 3 |
Ki = 3.9 nM
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CP0957904
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-4-phenylbutanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C57H89N15O12
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3
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| 1 |
EC50 = 4 nM
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| 2 |
EC50 = 151 nM
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| 3 |
Ki = 9.3 nM
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CP0955254
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(naphthalen-1-yl)propanoic acid
Show/Hide
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C64H91N15O12
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3
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| 1 |
EC50 = 4.5 nM
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| 2 |
EC50 = 123 nM
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| 3 |
Ki = 13 nM
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CP0871210
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-4-methylpentanoic acid
Show/Hide
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C57H91N15O12
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3
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| 1 |
EC50 = 4.6 nM
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| 2 |
EC50 = 149 nM
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| 3 |
Ki = 20 nM
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CP0544002
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16E,19S)-19-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,20-tetraoxo-1,4,7,10,14-pentazacycloicos-16-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C69H111N21O16
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4
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| 1 |
EC50 = 4.8 nM
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| 2 |
EC50 = 137 nM
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| 3 |
EC50 = 237 nM
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| 4 |
Ki = 2.5 nM
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CP0871208
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(S)-3-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-4-phenylbutanoic acid
Show/Hide
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C52H82N14O11
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3
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| 1 |
EC50 = 5.1 nM
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| 2 |
EC50 = 182 nM
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| 3 |
Ki = 19 nM
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CP0873940
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((2S)-2-((4R,7S,10S,13S,16S,19R)-19-((3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S)-36-((1H-imidazol-5-yl)methyl)-6,39-bis(2-amino-2-oxoethyl)-24,33-bis(4-aminobutyl)-1-((2S)-1-((2S)-5-guanidino-2-(5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidin-2-yl)-18,21,30-tris(3-guanidinopropyl)-12-((R)-1-hydroxyethyl)-9,27-diisobutyl-3-isopropyl-15-(2-(methylthio)ethyl)-1,4,7,10,13,16,19,22,25,28,31,34,37-tridecaoxo-2,5,8,11,14,17,20,23,26,29,32,35,38-tridecaazatetracontanamido)-13-(3-amino-3-oxopropyl)-7,10-bis(3-guanidinopropyl)-16-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamido)-4-(methylthio)butanoyl)pyrrolidin-2-yl)-9-(3-guanidinopropyl)-12-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C170H286N62O39S4
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4
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| 1 |
EC50 = 5.3 nM
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| 2 |
EC50 = 10 nM
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| 3 |
EC50 = 45 nM
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| 4 |
Ki = 0.19 nM
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CP0953634
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ELABELA
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C167H279N59O39S4
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3
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| 1 |
EC50 = 5.3 nM
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| 2 |
EC50 = 45 nM
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| 3 |
Ki = 0.19 nM
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CP0532921
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(2R)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(4-phenylmethoxyphenyl)propanoic acid
Show/Hide
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C52H77N13O12
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4
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| 1 |
EC50 = 5.3 nM
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| 2 |
EC50 = 161 nM
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| 3 |
EC50 = 301 nM
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| 4 |
Ki = 5.3 nM
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CP0544004
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
Show/Hide
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C42H73N13O11
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4
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| 1 |
EC50 = 5.4 nM
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| 2 |
EC50 = 249 nM
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| 3 |
EC50 = 743 nM
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| 4 |
Ki = 14 nM
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CP0885246
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8S,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-methyl-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C75H119N25O17S
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3
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| 1 |
EC50 = 5.7 nM
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| 2 |
EC50 = 288 nM
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| 3 |
Ki = 0.84 nM
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CP0479655
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]-prop-2-enylamino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]pent-4-enoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C75H116N22O15
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3
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| 1 |
EC50 = 5.7 nM
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| 2 |
EC50 = 232 nM
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| 3 |
Ki = 2.9 nM
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CP0528945
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2-[2-(1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C31H27N3O3
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1
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| 1 |
EC50 = 5.7 nM
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CP0532421
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2-[2-(1H-benzimidazol-2-yl)-5-methoxyphenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C32H29N3O4
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1
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| 1 |
EC50 = 5.7 nM
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CP0922755
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-3-sec-butyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H87N15O12
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3
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| 1 |
EC50 = 5.8 nM
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| 2 |
EC50 = 370 nM
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| 3 |
Ki = 16 nM
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CP0953642
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(R)-4-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-5-phenylpentanoic acid
Show/Hide
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C53H84N14O11
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3
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| 1 |
EC50 = 5.8 nM
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| 2 |
EC50 = 175 nM
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| 3 |
Ki = 8.9 nM
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CP0902112
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(9,10-dihydroanthracen-9-yl)propanoic acid
Show/Hide
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C78H116N22O16
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4
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| 1 |
EC50 = 6 nM
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| 2 |
EC50 = 95 nM
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| 3 |
IC50 = 13.7 nM
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| 4 |
Ki = 11 nM
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CP0454627
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(3S,6Z,9S,12S,15S,18S)-3,15-bis[3-(diaminomethylideneamino)propyl]-12-(2-methylpropyl)-2,11,14,17-tetraoxo-4-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,4,10,13,16-pentazabicyclo[16.3.0]henicos-6-ene-9-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C73H112N22O15
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3
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| 1 |
EC50 = 6 nM
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| 2 |
EC50 = 179 nM
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| 3 |
Ki = 4.5 nM
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CP0955252
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-3-benzyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-3-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C60H87N15O12
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3
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| 1 |
EC50 = 6.4 nM
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| 2 |
EC50 = 189 nM
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| 3 |
Ki = 25 nM
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CP0848441
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8S,11S,14S)-19-amino-11-(3-guanidinopropyl)-8-(hydroxymethyl)-19-imino-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C75H119N25O18S
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3
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| 1 |
EC50 = 6.5 nM
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| 2 |
EC50 = 229 nM
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| 3 |
Ki = 0.37 nM
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CP0848625
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-((4R,7S,10S,13S,16S,19R)-19-amino-13-(3-amino-3-oxopropyl)-7,10-bis(3-guanidinopropyl)-16-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamido)-4-(methylthio)butanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C84H136N28O19S3
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3
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| 1 |
EC50 = 6.6 nM
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| 2 |
EC50 = 151 nM
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| 3 |
Ki = 0.23 nM
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CP0542601
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C56H89N15O13
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7
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| 1 |
EC50 = 6.7 nM
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| 2 |
EC50 = 45 nM
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| 3 |
EC50 = 143 nM
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| 4 |
IC50 = 15 nM
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| 5 |
IC50 = 18 nM
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| 6 |
IC50 = 38 nM
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| 7 |
Ki = 4.6 nM
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CP0957737
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CLQRRCMPLHSRVPFP
Show/Hide
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C84H138N28O19S3
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3
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| 1 |
EC50 = 6.8 nM
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| 2 |
EC50 = 106 nM
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| 3 |
Ki = 0.34 nM
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CP0953635
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(2S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)octahydro-1H-indole-2-carboxylic acid
Show/Hide
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C60H93N15O12
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3
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| 1 |
EC50 = 6.9 nM
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| 2 |
EC50 = 172 nM
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| 3 |
Ki = 5.1 nM
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CP0871172
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C60H89N15O12
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3
|
| 1 |
EC50 = 7 nM
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|
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| 2 |
EC50 = 155 nM
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| 3 |
Ki = 16 nM
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CP0569863
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2-[5-chloro-2-(5-phenyl-1H-imidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C33H28ClN3O3
|
1
|
| 1 |
EC50 = 7.4 nM
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|
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CP0944657
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C56H87N15O12
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3
|
| 1 |
EC50 = 8 nM
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|
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| 2 |
EC50 = 309 nM
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| 3 |
Ki = 4.6 nM
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CP0545669
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6-butyl-5-(N-ethylanilino)-3-[3-(2-fluorophenyl)pyrrolidine-1-carbonyl]-4-hydroxy-1H-pyridin-2-one
Show/Hide
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C28H32FN3O3
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1
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| 1 |
EC50 = 8.4 nM
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|
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CP0848439
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-((S)-5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C75H119N25O17S2
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4
|
| 1 |
EC50 = 8.6 nM
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|
|
| 2 |
EC50 = 36 nM
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|
|
| 3 |
EC50 = 166 nM
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|
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| 4 |
Ki = 0.93 nM
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CP0507392
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6-butyl-3-{5-[(2- chlorophenyl) methyl]-1,3,4- oxadiazol- 2-yl}-5-(2,6- dimethoxyphenyl) pyridine-2,4-diol
Show/Hide
|
C26H26ClN3O5
|
1
|
| 1 |
EC50 = 8.6 nM
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|
|
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CP0533815
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2-[2-(1H-benzimidazol-2-yl)-4-chlorophenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
Show/Hide
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C31H26ClN3O3
|
1
|
| 1 |
EC50 = 9 nM
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|
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CP0859892
|
(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((6S,9S,12R)-1-amino-9-(3-guanidinopropyl)-1-imino-12-(mercaptomethyl)-7,10,13-trioxo-6-(5-oxopyrrolidine-2-carboxamido)-2,8,11,14-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C76H121N25O17S
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3
|
| 1 |
EC50 = 9.2 nM
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|
|
| 2 |
EC50 = 167 nM
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|
|
| 3 |
Ki = 0.14 nM
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CP0479656
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]pent-4-enoyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]pent-4-enoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C69H110N20O16
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3
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| 1 |
EC50 = 9.2 nM
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|
|
| 2 |
EC50 = 274 nM
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|
|
| 3 |
Ki = 1.9 nM
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CP0544005
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(2R)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Show/Hide
|
C45H71N13O12
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4
|
| 1 |
EC50 = 9.3 nM
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|
|
| 2 |
EC50 = 187 nM
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|
|
| 3 |
EC50 = 867 nM
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|
|
| 4 |
Ki = 16 nM
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|
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CP0902553
|
(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Show/Hide
|
C71H110N22O16
|
2
|
| 1 |
EC50 = 10 nM
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|
|
| 2 |
Ki = 0.07 nM
|
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|
|
CP0495402
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16E,19S)-19-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-14-(2-nitrophenyl)sulfonyl-3,6,9,20-tetraoxo-1,4,7,10,14-pentazacycloicos-16-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C64H97N17O17S
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4
|
| 1 |
EC50 = 10 nM
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|
|
| 2 |
EC50 = 403 nM
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|
|
| 3 |
EC50 = 441 nM
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|
|
| 4 |
Ki = 8.6 nM
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|
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CP0527204
|
2-butyl-3-(2,6-dimethoxyphenyl)-6-hydroxypyrimidin-4-one
Show/Hide
|
C16H20N2O4
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0955245
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-amino-4-(methylthio)butanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C55H85N15O12S
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3
|
| 1 |
EC50 = 11 nM
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|
|
| 2 |
EC50 = 581 nM
|
|
|
| 3 |
Ki = 16 nM
|
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|
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CP0514613
|
3-{5-[(4- chlorophenyl) methyl]-1,3,4- oxadiazol-2-yl}-6- cyclopropyl-5-(2,6- dimethoxyphenyl) pyridine-2,4-diol
Show/Hide
|
C25H22ClN3O5
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0447692
|
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]pentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoic acid
Show/Hide
|
C73H117N25O17S2
|
3
|
| 1 |
EC50 = 12 nM
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|
|
| 2 |
EC50 = 266 nM
|
|
|
| 3 |
Ki = 11 nM
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CP0554342
|
6-butyl-5-(N-ethylanilino)-4-hydroxy-3-[(3S)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0902032
|
A-R-R-C-M-P-L-H-S-R-V-P-F-P
Show/Hide
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C73H119N25O16S2
|
3
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
EC50 = 138 nM
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|
|
| 3 |
Ki = 0.53 nM
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CP0472299
|
2-butyl-3-(2,6-dimethoxyphenyl)-6-hydroxy-5-[(4-methoxyphenyl)methyl]pyrimidin-4-one
Show/Hide
|
C24H28N2O5
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0570145
|
3-(5-benzyl-1,3,4-oxadiazol-2-yl)-6-butyl-5-(2,6-dimethoxyphenyl)-4-hydroxy-1H-pyridin-2-one
Show/Hide
|
C26H27N3O5
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0573478
|
6-butyl-5-(N-ethylanilino)-4-hydroxy-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0573480
|
6-(cyclopropylmethyl)-3-[3-(3,5-difluoropyridin-2-yl)pyrrolidine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-1H-pyridin-2-one
Show/Hide
|
C27H28F2N4O3
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0380621
|
(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]pentanoyl]amino]-3-sulfanylpropanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C73H115N25O17S
|
3
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 316 nM
|
|
|
| 3 |
Ki = 3.4 nM
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CP0848442
|
(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-19-imino-8-(mercaptomethyl)-11-methyl-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C72H112N22O17S2
|
3
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 338 nM
|
|
|
| 3 |
Ki = 6.8 nM
|
|
|
|
CP0848624
|
(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-3-isobutyl-15-isopropyl-9-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C75H119N25O16S2
|
3
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 82 nM
|
|
|
| 3 |
Ki = 0.14 nM
|
|
|
|
CP0944656
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-15-benzyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C60H87N15O12
|
3
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
EC50 = 533 nM
|
|
|
| 3 |
Ki = 18 nM
|
|
|
|
CP0955645
|
(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoic acid
Show/Hide
|
C77H116N22O17
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 0.02 nM
|
|
|
|
CP0885245
|
CMPLHSRVPFP
Show/Hide
|
C58H90N16O13S2
|
4
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
EC50 = 476 nM
|
|
|
| 3 |
EC50 = 1064 nM
|
|
|
| 4 |
Ki = 14 nM
|
|
|
|
CP0859947
|
(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-12-(3-guanidinopropyl)-1-((2S)-1-((3S,6S,9R,12S)-6-(3-guanidinopropyl)-9-(mercaptomethyl)-3-methyl-1,4,7,10-tetraoxo-1-(5-oxopyrrolidin-2-yl)-15-thia-2,5,8,11-tetraazahexadecanecarbonyl)pyrrolidin-2-yl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C72H112N22O17S2
|
3
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 484 nM
|
|
|
| 3 |
Ki = 8.4 nM
|
|
|
|
CP0888277
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(2S)-1-((2S)-2-((2S)-1-((6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-24-((1H-imidazol-5-yl)methyl)-1-amino-9,30-bis(3-guanidinopropyl)-27-(hydroxymethyl)-1-imino-21-isobutyl-12-(mercaptomethyl)-18,34-dimethyl-15-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-6-(5-oxopyrrolidine-2-carboxamido)-2,8,11,14,17,20,23,26,29,32-decaazapentatriacontanecarbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C73H117N25O17S2
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3
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| 1 |
EC50 = 16 nM
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| 2 |
EC50 = 326 nM
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| 3 |
Ki = 4 nM
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CP0575162
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6-butyl-3-[4-[(2,3-dichlorophenyl)methyl]piperazine-1-carbonyl]-5-(N-ethylanilino)-4-hydroxy-1H-pyridin-2-one
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C29H34Cl2N4O3
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1
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| 1 |
EC50 = 16 nM
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CP0922756
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-cyclohexylpropanoyl)pyrrolidine-2-carboxylic acid
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C56H93N15O12
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3
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| 1 |
EC50 = 17 nM
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| 2 |
EC50 = 940 nM
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| 3 |
Ki = 4 nM
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CP0859893
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-3-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C72H113N25O17S2
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3
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| 1 |
EC50 = 19 nM
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| 2 |
EC50 = 942 nM
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| 3 |
Ki = 20 nM
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CP0393940
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S,5S,8S,11S,14S,16Z)-1-[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-11-(1H-imidazol-5-ylmethyl)-5-(2-methylpropyl)-3,6,9,12-tetraoxo-1,4,7,10,13-pentazacyclooctadec-16-ene-14-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C70H105N21O16
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3
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| 1 |
EC50 = 19 nM
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| 2 |
EC50 = 512 nM
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| 3 |
Ki = 9.1 nM
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CP0446912
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(3S,6S,12S,14Z,17S,20S)-12-[[(2R)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-butyl-2,5,11,19-tetraoxo-1,4,10,18-tetrazatricyclo[18.3.0.06,10]tricos-14-ene-17-carboxylic acid
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C67H108N22O16
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4
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| 1 |
EC50 = 19 nM
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| 2 |
EC50 = 272 nM
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| 3 |
EC50 = 469 nM
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| 4 |
Ki = 1.1 nM
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CP0445868
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2-[5-chloro-2-(3H-imidazo[4,5-c]pyridin-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
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C30H25ClN4O3
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1
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| 1 |
EC50 = 19 nM
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CP0956057
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(4-(benzyloxy)phenyl)propanoic acid
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C67H95N15O13
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3
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| 1 |
EC50 = 19 nM
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| 2 |
EC50 = 381 nM
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| 3 |
Ki = 19 nM
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CP0902547
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2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-2-benzyl-3-phenylpropanoic acid
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C77H116N22O16
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2
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| 1 |
EC50 = 19 nM
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| 2 |
Ki = 0.04 nM
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CP0866680
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(2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
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C75H120N26O16S2
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3
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| 1 |
EC50 = 20 nM
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| 2 |
EC50 = 1423 nM
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| 3 |
Ki = 22 nM
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CP0432703
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(2S)-2-[[(2S)-1-[(6S,9S,11Z,14S,17S)-6-(4-aminobutyl)-9-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-2,5,8,16-tetraoxo-1,4,7,15-tetrazabicyclo[15.3.0]icos-11-ene-14-carbonyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C66H102N20O16
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3
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| 1 |
EC50 = 20 nM
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| 2 |
EC50 = 400 nM
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| 3 |
Ki = 1.4 nM
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CP0554341
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6-butyl-5-(2,3-dihydroindol-1-yl)-4-hydroxy-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C28H31N3O3
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1
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| 1 |
EC50 = 21 nM
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CP0931323
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-12-((R)-1-hydroxyethyl)-1-imino-18,21,29-trimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C87H135N17O17
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1
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| 1 |
EC50 = 21.5 nM
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CP0888322
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C72H117N23O17S2
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3
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| 1 |
EC50 = 22 nM
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| 2 |
EC50 = 1730 nM
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| 3 |
Ki = 35 nM
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CP0432706
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(3S,6S,8Z,11S,14S,17S)-6-amino-3,14-bis[3-(diaminomethylideneamino)propyl]-2,5,13,16-tetraoxo-1,4,12,15-tetrazabicyclo[15.3.0]icos-8-ene-11-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C67H104N22O15
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3
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| 1 |
EC50 = 23 nM
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| 2 |
EC50 = 857 nM
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| 3 |
Ki = 5.7 nM
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CP0559667
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6-hydroxy-3-(2-methoxyphenyl)-2-propan-2-ylsulfanylpyrimidin-4-one
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C14H16N2O3S
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1
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| 1 |
EC50 = 23 nM
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CP0957089
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(naphthalen-1-yl)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C60H89N15O12
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3
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| 1 |
EC50 = 23 nM
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| 2 |
EC50 = 537 nM
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| 3 |
Ki = 21 nM
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CP0894417
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C73H115N25O17S2
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3
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| 1 |
EC50 = 24 nM
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| 2 |
EC50 = 1250 nM
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| 3 |
Ki = 20 nM
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CP0765197
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(R)-2-((S)-4-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-3-phenylpropanoic acid
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C77H113N23O16
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2
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| 1 |
EC50 = 25 nM
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| 2 |
Ki = 0.08 nM
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CP0466445
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2-[5-chloro-2-[(3-fluoro-4-methoxyphenyl)carbamoyl]phenyl]-5-(2,3-dihydro-1H-inden-5-ylcarbamoyl)benzoic acid
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C31H24ClFN2O5
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1
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| 1 |
EC50 = 29 nM
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CP0393938
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(2S)-2-[[(6S,8Z,11S,14S,17S)-14-butyl-6-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-2,5,13,16-tetraoxo-1,4,12,15-tetrazabicyclo[15.3.0]icos-8-ene-11-carbonyl]amino]-3-phenylpropanoic acid
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C67H101N21O16
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3
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| 1 |
EC50 = 30 nM
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| 2 |
EC50 = 825 nM
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| 3 |
Ki = 14 nM
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CP0910683
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)-2-methylpropanoic acid
Show/Hide
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C78H118N22O17
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2
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| 1 |
EC50 = 30 nM
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| 2 |
Ki = 6.1 nM
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CP0902551
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(R)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
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C79H114N22O16
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2
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| 1 |
EC50 = 32 nM
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| 2 |
Ki = 0.09 nM
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CP0954798
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(S)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Show/Hide
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C79H114N22O16
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2
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| 1 |
EC50 = 33 nM
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| 2 |
Ki = 0.08 nM
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CP0000753
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C88H137N17O18
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1
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| 1 |
EC50 = 33.7 nM
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CP0902552
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2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanoyl)-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Show/Hide
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C81H118N22O16
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2
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| 1 |
EC50 = 34 nM
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| 2 |
Ki = 0.16 nM
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CP0573479
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6-butyl-4-hydroxy-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-5-(N-propan-2-ylanilino)-1H-pyridin-2-one
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C29H35N3O3
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1
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| 1 |
EC50 = 35 nM
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CP0390355
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylideneamino)-2-[(5-oxopyrrolidine-2-carbonyl)amino]pentanoyl]amino]pentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C69H115N25O17S2
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3
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| 1 |
EC50 = 36 nM
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| 2 |
EC50 = 3646 nM
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| 3 |
Ki = 49 nM
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CP0902560
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2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanamido)-2-benzyl-3-phenylpropanoic acid
Show/Hide
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C85H120N22O16
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2
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| 1 |
EC50 = 36 nM
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| 2 |
Ki = 0.08 nM
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CP0902550
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(S)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(1H-indol-3-yl)propanamido)-3-phenylpropanoic acid
Show/Hide
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C76H113N23O16
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2
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| 1 |
EC50 = 38 nM
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| 2 |
Ki = 0.18 nM
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CP0562944
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6-butyl-4-hydroxy-5-(N-methylanilino)-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C27H31N3O3
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1
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| 1 |
EC50 = 38 nM
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CP0902559
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(2S,3R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-phenylbutanoic acid
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C71H112N22O16
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2
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| 1 |
EC50 = 40 nM
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| 2 |
Ki = 37 nM
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CP0910677
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(S)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanamido)-3-phenylpropanoic acid
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C78H114N22O16
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2
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| 1 |
EC50 = 41 nM
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| 2 |
Ki = 0.12 nM
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CP0379223
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C87H135N17O17
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1
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| 1 |
EC50 = 41.3 nM
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CP0570000
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3-(3-benzyl-1,2,4-oxadiazol-5-yl)-6-butyl-5-(2,6-dimethoxyphenyl)-4-hydroxy-1H-pyridin-2-one
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C26H27N3O5
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1
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| 1 |
EC50 = 43 nM
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CP0910682
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2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanoyl)-4-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
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C80H116N22O16
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2
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| 1 |
EC50 = 44 nM
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| 2 |
Ki = 0.4 nM
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CP0915429
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carbonyl)-7-(benzyloxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
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C78H116N22O17
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2
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| 1 |
EC50 = 45 nM
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| 2 |
Ki = 0.19 nM
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CP0562707
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(3S)-5-methyl-3-[[1-pentan-3-yl-2-(thiophen-2-ylmethyl)benzimidazole-5-carbonyl]amino]hexanoic acid
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C25H33N3O3S
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1
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| 1 |
EC50 = 47 nM
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CP0910681
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(biphenyl-3-yl)propanoic acid
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C76H114N22O16
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2
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| 1 |
EC50 = 47 nM
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| 2 |
Ki = 31 nM
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CP0445869
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2-[5-chloro-2-(4-methyl-1H-benzimidazol-2-yl)phenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
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C32H28ClN3O3
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1
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| 1 |
EC50 = 51 nM
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CP0521137
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2-[5-chloro-2-[(3-fluoro-4-methoxyphenyl)carbamoyl]phenyl]-5-[[(1S)-2-hydroxy-1-phenylethyl]carbamoyl]benzoic acid
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C30H24ClFN2O6
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1
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| 1 |
EC50 = 59 nM
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CP0942980
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(2S)-1-((3S,6S,9S,12S,15S,18S,21S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-21-benzyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-18-methyl-1,4,7,10,13,16,19-heptaoxo-2,5,8,11,14,17,20-heptaazadocosane)pyrrolidine-2-carboxylic acid
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C73H117N25O17S2
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3
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| 1 |
EC50 = 61 nM
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| 2 |
EC50 = 5182 nM
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| 3 |
Ki = 48 nM
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CP0572816
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6-butyl-4-hydroxy-5-(4-methoxy-N-methylanilino)-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C28H33N3O4
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1
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| 1 |
EC50 = 62 nM
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CP0943092
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(biphenyl-4-yl)propanoic acid
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C76H114N22O16
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2
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| 1 |
EC50 = 64 nM
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| 2 |
Ki = 35 nM
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CP0943236
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Show/Hide
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C71H110N22O16
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2
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| 1 |
EC50 = 67 nM
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| 2 |
Ki = 1.1 nM
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CP0902549
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)-3-cyclopentylphenyl)propanoic acid
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C82H124N22O17
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2
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| 1 |
EC50 = 69 nM
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| 2 |
Ki = 0.41 nM
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CP0955646
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-methyl-3-phenylbutanoic acid
Show/Hide
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C72H114N22O16
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2
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| 1 |
EC50 = 69 nM
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| 2 |
Ki = 0.36 nM
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CP0535319
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6-hydroxy-3-(2-methoxyphenyl)-2-(2-methylpropylsulfanyl)pyrimidin-4-one
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C15H18N2O3S
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1
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| 1 |
EC50 = 78 nM
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CP0549624
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6-hydroxy-2-propylsulfanyl-3-[2-(trifluoromethyl)phenyl]pyrimidin-4-one
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C14H13F3N2O2S
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1
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| 1 |
EC50 = 90 nM
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CP0487517
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5-[12-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylamino]dodecylsulfonyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C72H101N12O10S3+
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2
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| 1 |
EC50 = 90 nM
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| 2 |
Ki = 690 nM
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CP0943072
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(R)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-2-yl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Show/Hide
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C79H114N22O16
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2
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| 1 |
EC50 = 94 nM
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| 2 |
Ki = 0.37 nM
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CP0910680
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(R)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanamido)-3-(3,5-dicyclopentyl-4-hydroxyphenyl)propanoic acid
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C88H130N22O17
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2
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| 1 |
EC50 = 95 nM
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| 2 |
Ki = 1.1 nM
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CP0904874
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9-(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-15,21,29-trimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C82H133N17O17
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1
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| 1 |
EC50 = 95.7 nM
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CP0902557
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(R)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanamido)-3-(naphthalen-1-yl)propanoyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
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C81H115N23O16
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2
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| 1 |
EC50 = 96 nM
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| 2 |
Ki = 1.01 nM
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CP0562189
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6-hydroxy-3-(2-methylphenyl)-2-propylsulfanylpyrimidin-4-one
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C14H16N2O2S
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1
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| 1 |
EC50 = 100 nM
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CP0572073
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3-(2-ethoxyphenyl)-6-hydroxy-2-propylsulfanylpyrimidin-4-one
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C15H18N2O3S
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1
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| 1 |
EC50 = 100 nM
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CP0915430
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(S)-2-((2R,4S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)-4-(benzyloxy)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C77H116N22O17
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2
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| 1 |
EC50 = 100 nM
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| 2 |
Ki = 2.1 nM
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CP0902555
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(3-(benzyloxy)phenyl)propanoic acid
Show/Hide
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C77H116N22O17
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2
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| 1 |
EC50 = 106 nM
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| 2 |
Ki = 0.46 nM
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CP0538030
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3-(2-ethylphenyl)-6-hydroxy-2-propylsulfanylpyrimidin-4-one
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C15H18N2O2S
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1
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| 1 |
EC50 = 140 nM
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CP0943091
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(S)-2-((R)-2-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C75H112N22O16
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2
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| 1 |
EC50 = 142 nM
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| 2 |
Ki = 9.7 nM
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CP0890910
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(2S)-1-((2S)-2-((2S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((2S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-(5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-12-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C72H112N22O17S2
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3
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| 1 |
EC50 = 147 nM
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| 2 |
EC50 > 10000 nM
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| 3 |
Ki = 164 nM
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CP0562190
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3-(2-bromophenyl)-6-hydroxy-2-propylsulfanylpyrimidin-4-one
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C13H13BrN2O2S
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1
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| 1 |
EC50 = 155 nM
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CP0416053
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CHEMBL4639331
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C13H13FN2O2S
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1
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| 1 |
EC50 = 160 nM
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CP0546375
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6-butyl-3-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-5-(2,6-dimethoxyphenyl)-4-hydroxy-1H-pyridin-2-one
Show/Hide
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C25H24ClN3O5
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1
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| 1 |
EC50 = 180 nM
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CP0910679
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(2R,4S)-1-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carbonyl)-4-(benzyloxy)pyrrolidine-2-carboxylic acid
Show/Hide
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C73H114N22O17
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2
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| 1 |
EC50 = 192 nM
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| 2 |
Ki = 1 nM
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CP0398244
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C86H133N17O18
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1
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| 1 |
EC50 = 198.6 nM
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CP0560238
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2-butylsulfanyl-6-hydroxy-3-(2-methoxyphenyl)pyrimidin-4-one
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C15H18N2O3S
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1
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| 1 |
EC50 = 200 nM
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CP0902558
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2-((S)-4-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)acetic acid
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C77H115N23O17
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2
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| 1 |
EC50 = 221 nM
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| 2 |
Ki = 1.7 nM
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CP0398556
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(3S)-4-amino-3-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]pentanoyl]amino]-4-oxobutanoic acid
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C92H142N18O21
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1
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| 1 |
EC50 = 225.5 nM
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CP0472297
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3-(2-chlorophenyl)-6-hydroxy-2-propylsulfanylpyrimidin-4-one
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C13H13ClN2O2S
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1
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| 1 |
EC50 = 250 nM
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CP0535318
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6-hydroxy-3-(4-methylphenyl)-2-propylsulfanylpyrimidin-4-one
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C14H16N2O2S
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1
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| 1 |
EC50 = 260 nM
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CP0472293
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6-hydroxy-3-(3-methylphenyl)-2-propylsulfanylpyrimidin-4-one
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C14H16N2O2S
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1
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| 1 |
EC50 = 290 nM
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CP0910678
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2-((S)-4-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-oxo-4,5-dihydro-1H-naphtho[2,3-c]azepin-2(3H)-yl)acetic acid
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C75H114N24O17
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2
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| 1 |
EC50 = 311 nM
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| 2 |
Ki = 4.3 nM
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CP0422736
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3-(5-benzyl-1H-1,2,4-triazol-3-yl)-6-butyl-5-(2,6-dimethoxyphenyl)-4-hydroxy-1H-pyridin-2-one
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C26H28N4O4
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1
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| 1 |
EC50 = 330 nM
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CP0541051
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5-benzyl-6-hydroxy-3-(2-methoxyphenyl)-2-propylsulfanylpyrimidin-4-one
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C21H22N2O3S
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1
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| 1 |
EC50 = 340 nM
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CP0902554
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(3,5-dicyclopentyl-4-hydroxyphenyl)propanoic acid
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C80H126N22O17
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2
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| 1 |
EC50 = 361 nM
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| 2 |
Ki = 1.6 nM
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CP0902561
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)-3,5-dicyclopentylphenyl)propanoic acid
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C87H132N22O17
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2
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| 1 |
EC50 = 367 nM
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| 2 |
Ki = 13 nM
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CP0902548
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(R)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(biphenyl-2-yl)propanoic acid
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C76H114N22O16
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2
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| 1 |
EC50 = 391 nM
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| 2 |
Ki = 2.8 nM
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CP0538031
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6-hydroxy-3-(2-methoxyphenyl)-5-propan-2-yl-2-propylsulfanylpyrimidin-4-one
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C17H22N2O3S
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1
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| 1 |
EC50 = 450 nM
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CP0537336
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ethyl 6-butyl-5-(2,6-dimethoxyphenyl)-4-hydroxy-2-oxo-1H-pyridine-3-carboxylate
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C20H25NO6
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1
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| 1 |
EC50 = 450 nM
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CP0902556
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(S)-2-((2R,3R)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)-3-phenylpyrrolidine-2-carboxamido)-3-phenylpropanoic acid
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C76H114N22O16
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2
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| 1 |
EC50 = 454 nM
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| 2 |
Ki = 4.2 nM
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CP0472298
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6-hydroxy-3-(2-methoxyphenyl)-5-prop-2-enyl-2-propylsulfanylpyrimidin-4-one
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C17H20N2O3S
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1
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| 1 |
EC50 = 570 nM
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CP0943237
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1-amino-18-(4-aminobutyl)-6-((S)-1-((S)-5-guanidino-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanoyl)pyrrolidine-2-carboxamido)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)-2-methylpropanoic acid
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C78H118N22O17
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2
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| 1 |
EC50 = 571 nM
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| 2 |
Ki = 0.12 nM
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CP0575993
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6-hydroxy-3-(4-methoxyphenyl)-2-propylsulfanylpyrimidin-4-one
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C14H16N2O3S
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1
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| 1 |
EC50 = 680 nM
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CP0415929
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5-ethyl-6-hydroxy-3-(2-methoxyphenyl)-2-propylsulfanylpyrimidin-4-one
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C16H20N2O3S
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1
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| 1 |
EC50 = 860 nM
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CP0521333
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6-hydroxy-3-(3-methoxyphenyl)-2-propylsulfanylpyrimidin-4-one
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C14H16N2O3S
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1
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| 1 |
EC50 = 940 nM
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CP0521334
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6-hydroxy-3-(2-methoxyphenyl)-5-methyl-2-propylsulfanylpyrimidin-4-one
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C15H18N2O3S
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1
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| 1 |
EC50 = 1400 nM
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CP0525423
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5-butyl-6-hydroxy-3-(2-methoxyphenyl)-2-propylsulfanylpyrimidin-4-one
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C18H24N2O3S
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1
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| 1 |
EC50 = 1700 nM
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CP0402043
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2-[2-(1H-benzimidazol-2-yl)-3-chlorophenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
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C31H26ClN3O3
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1
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| 1 |
EC50 = 2100 nM
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CP0521348
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2-butan-2-ylsulfanyl-6-hydroxy-3-prop-2-enylpyrimidin-4-one
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C11H16N2O2S
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1
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| 1 |
EC50 = 4400 nM
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CP0471797
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2-[2-(1,3-benzoxazol-2-yl)-5-chlorophenyl]-5-[[(1R)-1-phenylbutyl]carbamoyl]benzoic acid
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C31H25ClN2O4
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1
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| 1 |
EC50 = 4900 nM
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CP0472292
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CHEMBL4635526
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C13H14N2O2S
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1
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| 1 |
EC50 = 5000 nM
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CP0379352
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]pyrrolidine-2-carboxamide
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C85H131N17O18
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1
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| 1 |
EC50 > 30000 nM
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CP0379353
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(2R)-N-[(2R)-1-[[(2R)-1-[[(2R)-1-[[(2R,3S)-1-[[(2R)-1-[[(2R,3S)-1-[[(2R)-1-[[(2R)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2R)-2-[[(2R,3S)-2-[[(2R)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C88H137N17O18
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1
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| 1 |
EC50 > 30000 nM
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CP0415077
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(2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C74H109N17O18
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1
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| 1 |
EC50 > 30000 nM
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CP0415078
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(hexadecanoylamino)-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C102H155N19O20
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1
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| 1 |
EC50 > 30000 nM
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CP0415079
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C60H100N10O11
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1
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| 1 |
EC50 > 30000 nM
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CP0521472
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C93H146N18O19
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1
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| 1 |
EC50 > 30000 nM
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CP0537853
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C80H132N16O18
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1
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| 1 |
EC50 > 30000 nM
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CP0566786
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(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-(hexadecanoylamino)-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
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C106H162N20O22
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1
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| 1 |
EC50 > 30000 nM
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CP0567921
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N-[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexadecanamide
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C86H135N17O18
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1
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| 1 |
EC50 > 30000 nM
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CP0567923
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(3S)-4-amino-3-[[(2S)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]pentanoyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoic acid
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C105H156N20O26
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1
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| 1 |
EC50 > 30000 nM
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CP0567924
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(3S)-4-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]pentanoyl]amino]-4-oxobutanoic acid
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C101H151N19O23
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1
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| 1 |
EC50 > 30000 nM
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CP0848014
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(S)-N-((2S,5S,8S,11S,14S,17S,20S)-17-((1H-indol-3-yl)methyl)-1-amino-2,8-bis(4-hydroxybenzyl)-5,11-bis((R)-1-hydroxyethyl)-14,22-dimethyl-1,4,7,10,13,16,19-heptaoxo-3,6,9,12,15,18-hexaazatricosan-20-yl)-1-((S)-2-((2S,3R)-2-((S)-2-(hexadecylamino)-3-methylbutanamido)-3-hydroxybutanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C82H127N13O16
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1
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| 1 |
EC50 > 30000 nM
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CP0858346
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-18-((R)-1-hydroxyethyl)-1-imino-12,21,29-trimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C87H135N17O17
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1
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| 1 |
EC50 > 30000 nM
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CP0904875
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-21-methyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazaoctacosan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C85H131N17O18
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1
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| 1 |
EC50 > 30000 nM
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CP0914642
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(S)-N-((2S,5S,8S,11S,14S,17S,20S,23S)-20-((1H-indol-3-yl)methyl)-1-amino-5,11-bis(4-hydroxybenzyl)-8,14-bis((R)-1-hydroxyethyl)-2,17,25-trimethyl-1,4,7,10,13,16,19,22-octaoxo-3,6,9,12,15,18,21-heptaazahexacosan-23-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-(N-methylpalmitamido)butanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C86H132N14O18
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1
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| 1 |
EC50 > 30000 nM
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CP0946319
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-21,29-dimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-palmitoylpyrrolidine-2-carboxamide
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C73H110N14O14
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1
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| 1 |
EC50 > 30000 nM
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CP0964290
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-21,29-dimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-palmitamidobutanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C83H128N16O17
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1
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| 1 |
EC50 > 30000 nM
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CP0964294
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(S)-N-((2R,3S,6S,9S,12S,15S,18S)-15-((1H-indol-3-yl)methyl)-3-carbamoyl-2-hydroxy-6-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-12,20-dimethyl-5,8,11,14,17-pentaoxo-4,7,10,13,16-pentaazahenicosan-18-yl)-1-((S)-2-((2S,3R)-3-hydroxy-2-((S)-3-methyl-2-palmitamidobutanamido)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamide
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C73H116N12O15
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1
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| 1 |
EC50 > 30000 nM
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CP0967505
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(S)-N-((6S,9S,12S,15S,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-1-amino-6-carbamoyl-9,15-bis(4-hydroxybenzyl)-12,18-bis((R)-1-hydroxyethyl)-1-imino-21,29-dimethyl-8,11,14,17,20,23,26-heptaoxo-2,7,10,13,16,19,22,25-octaazatriacontan-27-yl)-1-((S)-4-methyl-2-palmitamidopentanoyl)pyrrolidine-2-carboxamide
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C79H121N15O15
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1
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| 1 |
EC50 > 30000 nM
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CP0576405
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6-butyl-4-hydroxy-5-(2-methoxy-N-methylanilino)-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C28H33N3O4
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1
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| 1 |
EC50 > 75 nM
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CP0579346
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6-butyl-4-hydroxy-5-(3-methoxy-N-methylanilino)-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C28H33N3O4
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1
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| 1 |
EC50 > 75 nM
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CP0576406
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6-butyl-5-(3,4-dihydro-2H-quinolin-1-yl)-4-hydroxy-3-[(3R)-3-phenylpyrrolidine-1-carbonyl]-1H-pyridin-2-one
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C29H33N3O3
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1
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| 1 |
EC50 > 150 nM
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CP0909463
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(S)-2-((S)-1-((S)-2-((S)-1-((6S,9S,12S,15S,18S)-15-((1H-imidazol-5-yl)methyl)-1,6-diamino-18-(4-aminobutyl)-12-(hydroxymethyl)-1-imino-9-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosane)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoic acid
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C61H92N16O13
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2
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| 1 |
IC50 = 57 nM
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| 2 |
Ki = 46 nM
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CP0495260
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z)-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C56H88N14O13
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4
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| 1 |
IC50 = 97 nM
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| 2 |
IC50 = 164 nM
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| 3 |
IC50 = 198 nM
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| 4 |
Ki = 61 nM
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CP0544086
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-butyl-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C56H88N12O13
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4
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| 1 |
IC50 = 1111 nM
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| 2 |
IC50 = 1382 nM
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| 3 |
IC50 = 2347 nM
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| 4 |
Ki = 343 nM
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CP0445504
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2,6-diaminohexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-phenylmethoxyphenyl)propanoic acid
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C40H57N7O8
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0469829
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(2S)-3-(4-phenylmethoxyphenyl)-2-[[(2S)-1-[(2S)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid
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C32H42N4O6
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0954515
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(S)-2-((S)-1-((S)-2-((S)-1-(2-((S)-6-amino-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-3-(1H-imidazol-5-yl)propanamido)hexanamido)acetyl)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoic acid
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C49H69N11O11
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0962540
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(2S)-5-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid
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C79H128N18O16S2
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1
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| 1 |
Ki = 0.22 nM
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CP0965667
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(2S)-2-[3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-5-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
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C78H127N19O22S2
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1
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| 1 |
Ki = 0.25 nM
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CP0957394
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(2S)-5-[[(5S)-5-amino-6-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-6-oxo-hexyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid
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C85H140N20O17S2
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1
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| 1 |
Ki = 0.46 nM
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CP0965668
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(2S)-5-[[(5S)-6-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-[[4-[[(1R)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[(2S)-2-[[(1S)-1-benzyl-2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-4-oxo-butanoyl]amino]-6-oxo-hexyl]amino]-2-(hexadecanoylamino)-5-oxo-pentanoic acid
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C147H233N37O31S4
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1
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| 1 |
Ki = 0.6 nM
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CP0959036
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-((S)-5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C75H119N25O17S2
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1
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| 1 |
Ki = 0.93 nM
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CP0393936
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]pent-4-enoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]pent-4-enoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C72H110N22O16
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1
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| 1 |
Ki = 3.9 nM
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CP0962539
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CMPLHSRVPFP-amide
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C58H91N17O12S2
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1
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| 1 |
Ki = 5.07 nM
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CP0957395
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(S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-4-yl)methyl)-1-((S)-1-((5S,8R,11S,14S)-19-amino-11-(3-guanidinopropyl)-19-imino-8-(mercaptomethyl)-7,10,13-trioxo-14-((R)-5-oxopyrrolidine-2-carboxamido)-2-thia-6,9,12,18-tetraazanonadecanecarbonyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
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C75H120N26O16S2
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1
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| 1 |
Ki = 5.56 nM
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CP0579729
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S,5S,8S,11S,13Z,16S)-16-acetamido-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]-6-aminohexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C58H91N15O14
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1
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| 1 |
Ki = 28 nM
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CP0962724
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
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C61H89N15O12
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1
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| 1 |
Ki = 29 nM
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CP0495401
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(3-cyclopentyl-4-propoxyphenyl)propanoic acid
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C53H85N13O12
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1
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| 1 |
Ki = 33 nM
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CP0956055
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(2S,4R)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)-4-(benzyloxy)pyrrolidine-2-carboxylic acid
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C63H93N15O13
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1
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| 1 |
Ki = 38 nM
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CP0578008
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,19S)-19-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,13,20-pentaoxo-1,4,7,10,14-pentazacycloicosane-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C69H111N21O17
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1
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| 1 |
Ki = 39 nM
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CP0523147
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(1-aminoethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]-prop-2-enylamino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]amino]pent-4-enoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C74H115N21O16
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1
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| 1 |
Ki = 41 nM
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CP0572828
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S,5S,8S,11S,13Z,16S)-8-(4-aminobutyl)-16-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-(hydroxymethyl)-5-(1H-imidazol-5-ylmethyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C70H106N22O16
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1
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| 1 |
Ki = 41 nM
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CP0960934
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3,15-diisobutyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C57H89N15O12
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1
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| 1 |
Ki = 45 nM
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CP0955247
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(4-benzoylphenyl)propanoic acid
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C58H84N14O12
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1
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| 1 |
Ki = 48 nM
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CP0962726
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3,15-diisopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C55H85N15O12
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1
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| 1 |
Ki = 54 nM
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CP0962723
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(S)-2-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanamido)propanoic acid
Show/Hide
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C54H85N15O12
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1
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| 1 |
Ki = 57 nM
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CP0944659
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-indol-3-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C61H90N14O12
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1
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| 1 |
Ki = 62 nM
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CP0960933
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10,13-pentaoxo-15-propyl-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H87N15O12
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1
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| 1 |
Ki = 69 nM
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CP0565390
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1,3-thiazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C56H86N14O12S
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1
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| 1 |
Ki = 71 nM
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CP0960931
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(R)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H87N15O12
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1
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| 1 |
Ki = 72 nM
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CP0962330
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-12-(3-guanidinopropyl)-1-((S)-1-hexanoylpyrrolidin-2-yl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C56H86N14O12
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1
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| 1 |
Ki = 73 nM
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CP0955249
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(2S,4R)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)-4-hydroxypyrrolidine-2-carboxylic acid
Show/Hide
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C56H87N15O13
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1
|
| 1 |
Ki = 76 nM
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|
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CP0569304
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,16S)-16-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentazacycloheptadecane-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C66H105N21O17
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1
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| 1 |
Ki = 86 nM
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CP0571181
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(3-cyclopentyl-4-phenylmethoxyphenyl)propanoic acid
Show/Hide
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C57H85N13O12
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1
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| 1 |
Ki = 86 nM
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|
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CP0560015
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenefluoren-9-yl]benzenesulfonate
Show/Hide
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C60H77N12O9S3+
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1
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| 1 |
Ki = 89 nM
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CP0968445
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoic acid
Show/Hide
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C58H86N14O12
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1
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| 1 |
Ki = 92 nM
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|
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CP0966760
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(naphthalen-1-yl)propanoic acid
Show/Hide
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C55H82N14O11
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1
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| 1 |
Ki = 94 nM
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|
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CP0579730
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-1-ylpropanoic acid
Show/Hide
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C49H73N13O11
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1
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| 1 |
Ki = 109 nM
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CP0955251
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-2-((S)-1-((S)-2-aminohexanoyl)pyrrolidine-2-carbonyl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-16-methyl-4,7,10,13-tetraoxo-2,5,8,11,14-pentaazaheptadecanecarbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C57H89N15O12
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1
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| 1 |
Ki = 120 nM
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|
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CP0962331
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C51H80N14O11
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1
|
| 1 |
Ki = 128 nM
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|
|
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CP0578010
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-naphthalen-2-ylpropanoic acid
Show/Hide
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C49H73N13O11
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1
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| 1 |
Ki = 143 nM
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|
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CP0960935
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-15-(cyclohexylmethyl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C60H93N15O12
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1
|
| 1 |
Ki = 152 nM
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|
|
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CP0962332
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)azetidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C50H78N14O11
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1
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| 1 |
Ki = 159 nM
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|
|
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CP0528116
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopent-4-enoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]pent-4-enoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C58H93N15O13
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1
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| 1 |
Ki = 170 nM
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|
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CP0962334
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-15-tert-butyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C57H89N15O12
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1
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| 1 |
Ki = 174 nM
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|
|
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CP0543290
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)methylamino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylsulfamoyl]-2-[3,6-bis(diethylamino)-3H-xanthen-9-yl]benzenesulfonate
Show/Hide
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C61H80N12O10S3
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1
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| 1 |
Ki = 180 nM
|
|
|
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CP0957086
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(S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)piperidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C52H82N14O11
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1
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| 1 |
Ki = 186 nM
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|
|
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CP0548990
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,5S,8S,14S,16Z)-8-(4-aminobutyl)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]-2-(hydroxymethyl)-5-(1H-imidazol-5-ylmethyl)-3,6,9,12-tetraoxo-1,4,7,10,13-pentazacyclooctadec-16-ene-14-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
|
C71H110N22O16
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1
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| 1 |
Ki = 188 nM
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|
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CP0393937
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]pent-4-enoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]amino]pent-4-enoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C72H112N22O15
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1
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| 1 |
Ki = 194 nM
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CP0544003
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(3E,6S,9S,12S,15S,18S)-6-amino-9-[3-(diaminomethylideneamino)propyl]-15-(hydroxymethyl)-12-(2-methylpropyl)-7,10,13,16-tetraoxo-1,8,11,14,17,22-hexazabicyclo[18.3.0]tricosa-3,20,22-triene-18-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C60H93N17O13
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1
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| 1 |
Ki = 201 nM
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|
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CP0520210
|
(3S,6S,12S,17Z,20R,23S)-12-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-butyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
Show/Hide
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C69H113N23O16
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1
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| 1 |
Ki = 206 nM
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|
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CP0871174
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-3-benzyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C59H85N15O12
|
1
|
| 1 |
Ki = 212 nM
|
|
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CP0960930
|
(R)-3-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
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C51H80N14O11
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1
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| 1 |
Ki = 228 nM
|
|
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CP0572829
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,5S,11S,13Z,16S)-5-(4-aminobutyl)-16-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-2-(1H-imidazol-5-ylmethyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C70H108N22O15
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1
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| 1 |
Ki = 268 nM
|
|
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CP0943597
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S)-3-((1H-imidazol-5-yl)methyl)-1-(1-((S)-1-((S)-2-aminohexanoyl)pyrrolidine-2-carboxamido)cyclopropyl)-9-(3-guanidinopropyl)-6-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C54H81N15O12
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1
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| 1 |
Ki = 278 nM
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|
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CP0461773
|
(3S,6S,8Z,11S,14S,17S)-6-[[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-1-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]amino]-14-benzyl-3-butyl-2,5,13,16-tetraoxo-1,4,12,15-tetrazabicyclo[15.3.0]icos-8-ene-11-carboxylic acid
Show/Hide
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C73H113N23O17
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1
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| 1 |
Ki = 310 nM
|
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CP0495400
|
(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(3-cyclopentyl-4-cyclopentyloxyphenyl)propanoic acid
Show/Hide
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C55H87N13O12
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1
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| 1 |
Ki = 396 nM
|
|
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CP0578927
|
5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
Show/Hide
|
C60H77N12O10S3+
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1
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| 1 |
Ki = 400 nM
|
|
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CP0957905
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C54H83N15O12
|
1
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| 1 |
Ki = 419 nM
|
|
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CP0944658
|
(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-1-((S)-pyrrolidin-2-yl)-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C50H76N14O11
|
1
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| 1 |
Ki = 438 nM
|
|
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CP0572826
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(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]amino]pent-4-enoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]pent-4-enoic acid
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C75H117N23O17
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1
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| 1 |
Ki = 445 nM
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CP0958466
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15R)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C56H87N15O12
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1
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| 1 |
Ki = 463 nM
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CP0552890
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-cyclohexylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
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C59H95N13O12
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1
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| 1 |
Ki = 474 nM
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CP0393935
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pent-4-enoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]pent-4-enoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C68H100N18O16
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1
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| 1 |
Ki = 489 nM
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CP0492123
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(3S,5Z,8S,11S,14S,17S)-14-[3-(diaminomethylideneamino)propyl]-11-(2-methylpropyl)-2,10,13,16-tetraoxo-3-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-1,9,12,15-tetrazabicyclo[15.3.0]icos-5-ene-8-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C69H103N19O15
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1
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| 1 |
Ki = 509 nM
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CP0471113
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pent-4-enoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]pent-4-enoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C71H107N19O15
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1
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| 1 |
Ki = 523 nM
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CP0955246
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(S)-1-((S)-2-((S)-1-((2S,5S,8S,11S,14S,17S)-11-((1H-imidazol-5-yl)methyl)-17-amino-5-(3-guanidinopropyl)-8-(hydroxymethyl)-14-isobutyl-2-isopropyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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C48H74N14O11
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1
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| 1 |
Ki = 643 nM
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CP0425109
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-thiophen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
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C57H87N13O12S
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1
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| 1 |
Ki = 664 nM
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CP0960932
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(R)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)-2-benzylpyrrolidine-2-carboxylic acid
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C63H93N15O12
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1
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| 1 |
Ki = 916 nM
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CP0454620
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(3S,6S,12S,17Z,20S,23S)-12-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-butyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
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C69H113N23O16
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1
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| 1 |
Ki = 917 nM
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CP0572700
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C53H85N13O12
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1
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| 1 |
Ki = 1464 nM
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CP0571180
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(4-phenylmethoxyphenyl)propanoic acid
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C52H77N13O12
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1
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| 1 |
Ki = 2044 nM
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CP0495399
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(3,5-dicyclopentyl-4-phenylmethoxyphenyl)propanoic acid
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C62H93N13O12
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1
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| 1 |
Ki = 2670 nM
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CP0572827
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S,5S,8S,11S,13Z,16S)-16-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(hydroxymethyl)-8-(1H-imidazol-5-ylmethyl)-2-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C66H96N18O16
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1
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| 1 |
Ki = 6074 nM
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CP0432704
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(3S,6S,12S,17Z,20S,23S)-12-amino-3-butyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
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C26H42N6O6
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1
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| 1 |
Ki > 10000 nM
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CP0572830
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(3S,6S,12S,17Z,20S,23S)-12-amino-3-butyl-15-(2-nitrophenyl)sulfonyl-2,5,11,22-tetraoxo-1,4,10,15,21-pentazatricyclo[21.3.0.06,10]hexacos-17-ene-20-carboxylic acid
Show/Hide
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C32H45N7O10S
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1
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| 1 |
Ki > 10000 nM
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CP0558159
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C63H91N13O12
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1
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| 1 |
Ki > 10000 nM
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CP0562561
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]pentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C55H90N14O12
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1
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| 1 |
Ki > 10000 nM
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CP0562815
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]butanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C54H88N14O12
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1
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| 1 |
Ki > 10000 nM
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CP0564810
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C59H89N13O12
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1
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| 1 |
Ki > 10000 nM
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CP0572701
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(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-naphthalen-1-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C63H91N13O12
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1
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| 1 |
Ki > 10000 nM
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CP0871173
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(S)-1-((S)-2-((S)-1-(1-((3S,6S,9S,12S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecanamido)cyclopropanecarbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C55H83N15O12
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1
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| 1 |
Ki > 10000 nM
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CP0955248
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(S)-4-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)pentanoic acid
Show/Hide
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C47H80N14O11
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1
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| 1 |
Ki > 10000 nM
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CP0955250
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(4-benzoylphenyl)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C63H91N15O13
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1
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| 1 |
Ki > 10000 nM
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CP0956056
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C50H83N15O12
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1
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| 1 |
Ki > 10000 nM
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CP0957087
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(3S,6S,9S,12S,15S,21S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-21-benzyl-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-18,18-dimethyl-1,4,7,10,13,16,19-heptaoxo-2,5,8,11,14,17,20-heptaazadocosan-22-oic acid
Show/Hide
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C50H80N14O11
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1
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| 1 |
Ki > 10000 nM
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CP0957088
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(biphenyl-4-yl)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C62H91N15O12
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1
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| 1 |
Ki > 10000 nM
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CP0959037
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(S)-1-((S)-2-((S)-1-((2S,5S,8S,11S,14S)-11-((1H-imidazol-5-yl)methyl)-14-amino-5-(3-guanidinopropyl)-8-(hydroxymethyl)-2-isopropyl-16-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazaheptadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C45H69N13O10
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1
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| 1 |
Ki > 10000 nM
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CP0960929
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(S)-1-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)-3-hydroxypropanamido)-5-guanidinopentanamido)-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C39H58N12O9
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1
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| 1 |
Ki > 10000 nM
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CP0962333
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(S)-2-(1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecanamido)cyclopropanecarboxamido)-3-phenylpropanoic acid
Show/Hide
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C50H78N14O11
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1
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| 1 |
Ki > 10000 nM
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CP0966005
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(S)-1-((S)-2-((S)-1-((3S,6S,9S,12S,15S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-15-isopropyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecane)pyrrolidine-2-carboxamido)-3-(4-(benzyloxy)phenyl)propanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C63H93N15O13
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1
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| 1 |
Ki > 10000 nM
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CP0967108
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(S)-1-((S)-2-((S)-1-(1-((3S,6S,9S,12S)-6-((1H-imidazol-5-yl)methyl)-1-((S)-1-((S)-2-aminohexanoyl)pyrrolidin-2-yl)-12-(3-guanidinopropyl)-9-(hydroxymethyl)-3-isobutyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecanamido)cyclopentanecarbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Show/Hide
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C57H87N15O12
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1
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| 1 |
Ki > 10000 nM
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CP0532919
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(2S)-2-[[(2S)-1-[5-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
Show/Hide
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C39H67N11O10
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1
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| 1 |
Ki > 10000 nM
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CP0544085
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(2S)-2-[[(2S)-1-[2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
Show/Hide
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C36H61N11O10
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1
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| 1 |
Ki > 10000 nM
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CP0575899
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(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]propanoic acid
Show/Hide
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C39H67N13O11
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1
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| 1 |
Ki > 10000 nM
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CP0578009
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(2S)-6-amino-2-[[(2S,5S,8S,11S,13Z,16S)-16-amino-2-[3-(diaminomethylideneamino)propyl]-8-(hydroxymethyl)-5-(2-methylpropyl)-3,6,9,17-tetraoxo-1,4,7,10-tetrazacycloheptadec-13-ene-11-carbonyl]amino]hexanoic acid
Show/Hide
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C29H52N10O8
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1
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| 1 |
Ki > 10000 nM
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