Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(3S,6Z,9S,12S,15S,18S)-3,15-bis[3-(diaminomethylideneamino)propyl]-12-(2-methylpropyl)-2,11,14,17-tetraoxo-4-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,4,10,13,16-pentazabicyclo[16.3.0]henicos-6-ene-9-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
    Show/Hide
 PubChem ID
CID: 137660518
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1C\C=C/CN([C@@H](CCCNC(N)=N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N1)C(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
    Show/Hide
Compound Formula C73H112N22O15
Compound Structure
Protein Name
 Protein Info 
Apelin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neuropeptide receptor
Uniprot ID
P35414
Gene Name
APLNR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
2
EC50 = 179 nM
   TI
   LI
   LO
   TS
3
Ki = 4.5 nM
   TI
   LI
   LO
   TS