Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-1-((2S)-2-((2S)-1-((6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-24-((1H-imidazol-5-yl)methyl)-1-amino-9,30-bis(3-guanidinopropyl)-27-(hydroxymethyl)-1-imino-21-isobutyl-12-(mercaptomethyl)-18,34-dimethyl-15-(2-(methylthio)ethyl)-7,10,13,16,19,22,25,28,31-nonaoxo-6-(5-oxopyrrolidine-2-carboxamido)-2,8,11,14,17,20,23,26,29,32-decaazapentatriacontanecarbonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
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 PubChem ID
CID: 145948663
Canonical SMILES
CSCC[C@@H](NC(=O)[C@@H](CS)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C1CCC(=O)N1)C(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](Cc1cnc[nH]1)C(=O)N[C@H](CO)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](C(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)O)C(C)C
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Compound Formula C73H117N25O17S2
Compound Structure
Protein Name
 Protein Info 
Apelin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
P35414
Gene Name
APLNR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 16 nM
   TI
   LI
   LO
   TS
2
EC50 = 326 nM
   TI
   LI
   LO
   TS
3
Ki = 4 nM
   TI
   LI
   LO
   TS