Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL5170657
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Canonical SMILES
CCc1cccc(CC)c1-n1c(O)c(C(=O)N2CC[C@H](C2)c2ncc(Cl)cc2F)c(=O)nc1-c1ccn(C)n1
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Compound Formula C28H28ClFN6O3
Compound Structure
Protein Name
 Protein Info 
Apelin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
P35414
Gene Name
APLNR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.06 nM
   TI
   LI
   LO
   TS
CL000524 HEK293-FT
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.07 nM
   TI
   LI
   LO
   TS