| Compound ID |
Compound Name |
Compound Formula |
|
CP0663338
|
N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-((2,3-dihydrobenzofuran-6-yl)methylamino)-5-((1R,5S)-8-isopropyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)nicotinamide
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|
C34H38N4O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
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CP0849540
|
3-(Difluoromethyl)-4-methylbenzyl 2-((benzo[d][1,3]-dioxol-5-ylmethyl)amino)-5-(3-hydroxy-3-methylbut-1-yn-1-yl)nicotinate
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|
C28H27F2N3O4
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0873715
|
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(3-chloro-4-methoxybenzyl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)nicotinamide
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|
C33H35ClN4O4
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0865055
|
5-((1R,5S)-8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-((benzo[d][1,3]dioxol-5-ylmethyl)amino)-N-(3-chloro-4-methoxybenzyl)nicotinamide
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|
C32H33ClN4O5
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
|
CP0852605
|
5-(3-Acetamido-3-methylbut-1-yn-1-yl)-2-((benzo[d]-[1,3]dioxol-5-ylmethyl)amino)-N-(3-chloro-4-methoxybenzyl)-nicotinamide
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|
C29H29ClN4O5
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0869061
|
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)-N-(2-phenoxyethyl)nicotinamide
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|
C33H36N4O4
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0663159
|
5-((1R,5S)-8-acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-((2,3-dihydrobenzofuran-6-yl)methylamino)nicotinamide
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|
C33H34N4O5
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0884346
|
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)nicotinamide
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|
C34H36N4O5
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0865025
|
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-((benzo-[d][1,3]dioxol-5-ylmethyl)amino)-N-(2-phenoxyethyl)nicotinamide
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|
C32H34N4O5
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0875779
|
(S)-2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-(1-ethyl-1H-pyrazol-4-yl)nicotinamide
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|
C28H27N5O5
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0432495
|
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,3-dihydro-1-benzofuran-6-ylmethylamino)-5-(1-propylpyrazol-4-yl)pyridine-3-carboxamide
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|
C30H31N5O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0708284
|
(S)-N1-((2S,5S,8S,11S,14S)-8-((1H-indol-3-yl)methyl)-5-benzyl-14-carbamoyl-1-(1H-indol-3-yl)-11-isobutyl-16-methyl-3,6,9,12-tetraoxo-4,7,10,13-tetraazaheptadecan-2-yl)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carboxamido)hexanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)pentanediamide
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|
C79H109N19O12
|
2
|
| 1 |
IC50 = 146 nM
|
|
|
| 2 |
IC50 = 250 nM
|
|
|
|
CP0413122
|
2-(1,3-benzodioxol-5-ylmethylamino)-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-5-(1-propylpyrazol-4-yl)pyridine-3-carboxamide
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|
C29H29N5O5
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0708338
|
N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-((2,3-dihydrobenzofuran-6-yl)methylamino)-5-((2S,6R)-2,6-dimethylmorpholino)nicotinamide
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|
C30H34N4O5
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0706900
|
Rac-2'-chloro-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-6-((2,3-dihydrobenzofuran-6-yl)methylamino)-3,4'-bipyridine-5-carboxamide
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|
C29H25ClN4O4
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
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CP0801303
|
Rac-2-(benzo[b]thiophen-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-(1-propyl-1H-pyrazol-4-yl)nicotinamide
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|
C30H29N5O3S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0850765
|
2-(benzo[d][1,3]dioxol-5-ylmethylamino)-5-((1R,5S)-8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)nicotinamide
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|
C29H30N4O6
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0708283
|
2-(benzofuran-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-(1-propyl-1H-pyrazol-4-yl)nicotinamide
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|
C30H29N5O4
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0865428
|
2-(benzo[d]thiazol-6-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-(1-propyl-1H-pyrazol-4-yl)nicotinamide
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|
C29H28N6O3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
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CP0721096
|
(S)-2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-morpholinonicotinamide
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|
C27H28N4O6
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0683137
|
(S)-5-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)-2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)nicotinamide
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|
C30H30N4O6
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0708282
|
(R)-2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-5-(1-ethyl-1H-pyrazol-4-yl)nicotinamide
Show/Hide
|
C28H27N5O5
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
