Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(Difluoromethyl)-4-methylbenzyl 2-((benzo[d][1,3]-dioxol-5-ylmethyl)amino)-5-(3-hydroxy-3-methylbut-1-yn-1-yl)nicotinate
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 PubChem ID
CID: 122182190
Canonical SMILES
Cc1ccc(CNC(=O)c2cc(C#CC(C)(C)O)cnc2NCc2ccc3c(c2)OCO3)cc1C(F)F
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Compound Formula C28H27F2N3O4
Compound Structure
Protein Name
 Protein Info 
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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GRP-related receptor
Uniprot ID
O08725
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 0.28 nM
   TI
   LI
   LO
   TS
2
IC50 = 13 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.4 nM
   TI
   LI
   LO
   TS