Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04108 , Atypical chemokine receptor 3
Gene Name ACKR3
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25106
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04108
 
Compound ID Compound Name Compound Formula
CP0389912
N-[(E)-3-(2-fluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H35FN2O4
 2
1
EC50 = 14.1 nM
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2
Ki = 7.943 nM
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CP0389913
N-[(E)-3-(2-fluorophenyl)-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H33FN2O3
 2
1
EC50 = 23.7 nM
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2
Ki = 19.95 nM
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CP0573743
(3R,6S,9S,12S,15S,20S,23S,26S,29S,32S)-6-(4-aminobutyl)-N-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-26-(3-carbamimidamidopropyl)-3,9,23-tris[3-(carbamoylamino)propyl]-12,29-bis[(4-hydroxyphenyl)methyl]-2,5,8,11,14,22,25,28,31-nonaoxo-17,18-dithia-1,4,7,10,13,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-20-carboxamide
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C90H140N34O19S2
 1
1
EC50 = 350 nM
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CP0567856
(1S,14E)-14-ethylidene-3,12-diazatetracyclo[10.2.2.02,10.04,9]hexadeca-2(10),4,6,8-tetraene
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C16H18N2
 1
1
EC50 = 27000 nM
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CP0517201
N-[(3S,4S)-1-(cyclopropylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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C27H28F2N6O3
 1
1
Ki = 0.53 nM
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CP0408903
3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-N-[(E)-3-phenylbut-2-enyl]benzamide
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C27H36N2O4
 1
1
Ki = 12.59 nM
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CP0481057
3,4,5-trimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H36N2O4
 1
1
Ki = 15.85 nM
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CP0433294
3,4-dimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H34N2O3
 1
1
Ki = 25.12 nM
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CP0400097
N-[(E)-3-(2,4-difluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H34F2N2O4
 1
1
Ki = 31.62 nM
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CP0482044
N-[(E)-3-(4-fluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H35FN2O4
 1
1
Ki = 50.12 nM
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CP0400099
N-[(E)-3-(3-fluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H35FN2O4
 1
1
Ki = 79.43 nM
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CP0408904
N-[(E)-3-(4-fluorophenyl)-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H33FN2O3
 1
1
Ki = 79.43 nM
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CP0430599
N-[(E)-3-(3-fluorophenyl)-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H33FN2O3
 1
1
Ki = 100 nM
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CP0482043
N-[(E)-3-(2,4-difluorophenyl)-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H32F2N2O3
 1
1
Ki = 100 nM
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CP0482041
3,4,5-trimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[3-(2-methylpiperidin-1-yl)propyl]benzamide
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C29H40N2O4
 1
1
Ki = 199.53 nM
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CP0426195
3,4,5-trimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-(3-morpholin-4-ylpropyl)benzamide
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C27H36N2O5
 1
1
Ki = 398.11 nM
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CP0433293
3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-N-[(E)-3-phenylprop-2-enyl]benzamide
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C26H34N2O4
 1
1
Ki = 794.33 nM
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CP0433295
4-methoxy-3-methyl-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H34N2O2
 1
1
Ki = 794.33 nM
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CP0482042
N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide
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C26H32N2O3
 1
1
Ki = 794.33 nM
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CP0400096
2,4-dimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C26H34N2O3
 1
1
Ki = 1258.93 nM
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CP0400101
N-[(E)-3-(2-fluoro-4-methoxyphenyl)-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H35FN2O4
 1
1
Ki = 1258.93 nM
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CP0412493
N-[(E)-3-(2-fluoro-4-methoxyphenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C28H37FN2O5
 1
1
Ki = 1258.93 nM
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CP0400095
N-(3-hydroxypropyl)-3,4,5-trimethoxy-N-[(E)-2-methyl-3-phenylprop-2-enyl]benzamide
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C23H29NO5
 1
1
Ki = 1584.89 nM
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CP0482045
N-[(E)-3-(2,4-difluorophenyl)-2-methylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide
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C26H30F2N2O3
 1
1
Ki = 1584.89 nM
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CP0499037
N-[(E)-3-(2,4-difluorophenyl)-2-methylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-1,3-benzodioxole-5-carboxamide
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C25H28F2N2O3
 1
1
Ki = 3162.28 nM
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CP0400100
N-[(E)-3-[3-fluoro-5-(trifluoromethyl)phenyl]-2-methylprop-2-enyl]-3,4-dimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C27H32F4N2O3
 1
1
Ki = 5011.87 nM
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CP0488113
N-[(E)-3-[3-fluoro-5-(trifluoromethyl)phenyl]-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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C28H34F4N2O4
 1
1
Ki = 5011.87 nM
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