General Information of the Compound
Compound ID
CP0482042
Compound Name
N-[(E)-2-methyl-3-phenylprop-2-enyl]-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide
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Structure
Formula
C26H32N2O3
Molecular Weight
420.553
Canonical SMILES
CN1CCCC1CCN(C\C(C)=C\c1ccccc1)C(=O)c1ccc2OCCOc2c1
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InChI
InChI=1S/C26H32N2O3/c1-20(17-21-7-4-3-5-8-21)19-28(14-12-23-9-6-13-27(23)2)26(29)22-10-11-24-25(18-22)31-16-15-30-24/h3-5,7-8,10-11,17-18,23H,6,9,12-16,19H2,1-2H3/b20-17+
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InChIKey
GTCPVFWDKLPXPL-LVZFUZTISA-N
Physicochemical Property
logP
4.4878
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
42.01
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 59052141
SID: 140106878
ChEMBL ID
CHEMBL2013221
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04108, Atypical chemokine receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 794.33 nM
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