Brief Information of the Compound and Protein
Compound Name
N-[(E)-3-(2-fluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
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PubChem ID
CID: 59052285
SID: 140107039
Canonical SMILES
COc1cc(cc(OC)c1OC)C(=O)N(CCC1CCCN1C)C\C(C)=C\c1ccccc1F
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Compound Formula C27H35FN2O4
Compound Structure
Protein Name
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 1.6 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 14.1 nM
   TI
   LI
   LO
   TS
2
Ki = 7.943 nM
   TI
   LI
   LO
   TS